Results 31 to 40 of about 830,008 (409)

Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]

open access: yes, 2020
Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter   +7 more
core   +1 more source

The visceral adiposity index is associated with insulin sensitivity and IGF-I levels in adults with growth hormone deficiency [PDF]

open access: yes, 2016
The visceral adiposity index, based on anthropometric and metabolic parameters, has been shown to be related to adipose tissue function and insulin sensitivity.
Ciresi, A.   +3 more
core   +1 more source

Neuroprotective effects of insulin-like growth factor-2 in 6-hydroxydopamine-induced cellular and mouse models of Parkinson’s disease

open access: yesNeural Regeneration Research, 2023
Skin-derived precursor Schwann cells have been reported to play a protective role in the central nervous system. The neuroprotective effects of skin-derived precursor Schwann cells may be attributable to the release of growth factors that nourish host ...
Hai-Ying Zhang   +7 more
doaj   +1 more source

Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]

open access: yes, 2011
Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey   +39 more
core   +2 more sources

The effect of ulipristal acetate on tumor necrosis factor α, insulin-like growth factor 1, and plasminogen activator inhibitor-1 serum levels in patients with symptomatic uterine fibroids

open access: yesArchives of Medical Science, 2020
Introduction Uterine fibroids (UFs) are benign tumors of the female reproductive system originating from the smooth muscle of the uterus. Currently, progesterone is known to play a key role in the differentiation of the myometrial tissue to form UFs and ...
Michał Ciebiera   +7 more
doaj   +1 more source

Development of real-time reverse transcription polymerase chain reaction assays to quantify insulin-like growth factor receptor and insulin receptor expression in equine tissue

open access: yesOnderstepoort Journal of Veterinary Research, 2013
The insulin-like growth factor system (insulin-like growth factor 1, insulin-like growth factor 2, insulin-like growth factor 1 receptor, insulin-like growth factor 2 receptor and six insulin-like growth factor-binding proteins) and insulin are essential
Stephen B. Hughes   +3 more
doaj   +1 more source

The ovarian insulin-like growth factor system.

open access: yesJournal of reproduction and fertility. Supplement, 2019
The growth and development of the ovarian follicle entails a co-ordinated process of cell replication and differentiation during which the number of granulosa cells lining the follicle may increase dramatically and daughter cells emerge with a different ...
JM Hammond   +3 more
semanticscholar   +1 more source

Insulin-like growth factor -I deficiency, insulin sensitivity, and glucose metabolism [PDF]

open access: yes, 2013
In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. In contrast,
Ekström, Klas
core   +1 more source

Revisiting the IGF-1R as a breast cancer target

open access: yesnpj Precision Oncology, 2017
The type I insulin-like growth factor-1 receptor is a well-described target in breast cancer and multiple clinical trials examining insulin-like growth factor-1 receptor have been completed.
Roudy Chiminch Ekyalongo, Douglas Yee
doaj   +1 more source

Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients

open access: yesBMC Research Notes, 2019
Objective The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are thought to play a significant role in metabolic pathways and glucose metabolism.
Somayeh Pouriamehr   +4 more
doaj   +1 more source

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