Results 41 to 50 of about 428,788 (310)
Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar
Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal +6 more
doaj +1 more source
Effect of Iron Deficiency Anemia on IGF-1 Level Among Sample of Children
Advanced Medical Journal, 2023 Background and objectives:Iron-deficiency anemia is a worldwide nutritional problem and an important public health problem especially in developing countries.
Kani Rast Noori +1 more
doaj +1 more source
Expression of the insulin-like growth factor-II/mannose-6-phosphate receptor in multiple human tissues during fetal life and early infancy [PDF]
, 1992 The insulin like growth factor-II/mannose-6-phosphate (IGF-II/M6P) receptor has been detected in many cells and tissues. In the rat, there is a dramatic developmental regulation of IGF-II/M6P receptor expression, the receptor being high in fetal and ...
Eisenmenger, Wolfgang +5 more
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BMC Endocrine Disorders, 2018 Background Insulin and insulin-like growth factor (IGF)-1 coupled with growth hormone helps control timing of sexual maturation. Mutations and variants in multiple genes are associated with development or reduced risk of central precocious puberty (CPP).
Hua-Pin Chang +3 more
doaj +1 more source
Growth Hormone, Insulin-Like Growth Factors, and the Skeleton [PDF]
Endocrine Reviews, 2008 GH and IGF-I are important regulators of bone homeostasis and are central to the achievement of normal longitudinal bone growth and bone mass. Although GH may act directly on skeletal cells, most of its effects are mediated by IGF-I, which is present in the systemic circulation and is synthesized by peripheral tissues.
GIUSTINA, Andrea +2 more
openaire +4 more sources
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Insulin-Like Growth Factors and the Brain [PDF]
Endocrinology, 2008 The IGFs have interested biologists and physicians for many decades; starting with the somatomedin hypothesis as presented by Daughaday and Salmon in 1957 (1). It was initially thought that somatomedin C (IGF-I) was the liver-derived, circulating form of IGF and controlled postnatal growth in response to GH. After the advent of molecular endocrinology,
openaire +2 more sources