Results 31 to 40 of about 428,788 (310)

Development of real-time reverse transcription polymerase chain reaction assays to quantify insulin-like growth factor receptor and insulin receptor expression in equine tissue

Onderstepoort Journal of Veterinary Research, 2013
The insulin-like growth factor system (insulin-like growth factor 1, insulin-like growth factor 2, insulin-like growth factor 1 receptor, insulin-like growth factor 2 receptor and six insulin-like growth factor-binding proteins) and insulin are essential
Stephen B. Hughes, Melvyn Quan, Alan Guthrie, Martin Schulman   +3 more
doaj   +1 more source

Neuroprotective effects of insulin-like growth factor-2 in 6-hydroxydopamine-induced cellular and mouse models of Parkinson’s disease

Neural Regeneration Research, 2023
Skin-derived precursor Schwann cells have been reported to play a protective role in the central nervous system. The neuroprotective effects of skin-derived precursor Schwann cells may be attributable to the release of growth factors that nourish host ...
Hai-Ying Zhang, Yong-Cheng Jiang, Jun-Rui Li, Jia-Nan Yan, Xin-Jue Wang, Jia-Bing Shen, Kai-Fu Ke, Xiao-Su Gu   +7 more
doaj   +1 more source

Insulin-Like Growth Factor II (IGF-II) Is More Potent Than IGF-I in Stimulating Cortisol Secretion from Cultured Bovine Adrenocortical Cells: Interaction with the IGF-I Receptor and IGF-Binding Proteins [PDF]

, 1995
Although the stimulating effect of insulin-like growth factor I (IGF-I) on adrenal steroidogenesis has been well established, the role of IGF-II in the adult adrenal gland remains unknown.
Weber, Matthias M., Fottner, Christian, Simmler, Pia, Engelhardt, Dieter   +3 more
core   +1 more source

Insulin-like growth factor-II: new roles for an old actor

Frontiers in Endocrinology, 2012
IGF-II, traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator.
Stefano eCianfarani
doaj   +1 more source

Effects of Insulin-Like Growth Factor (IGF-1) in Patients with Sensorineural Hearing Loss

, 2021
OBJECTIVES: (1) To test the effect of local administration of insulin-like growth factor-1 (IGF-1) in patients with sensorineural hearing loss (SNHL). (2) To test the effect of local administration of IGF-1 in patients with ototoxicity.
Varun Jitendra Dave, Kshitij Shah, Manish Prajapati, Joshi, Anagha, Shah, Kshitij, Renuka Bradoo, Dave, Varun Jitendra, Prajapati, Manish, Bradoo, Renuka, Anagha Joshi   +9 more
core   +1 more source

Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients

BMC Research Notes, 2019
Objective The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are thought to play a significant role in metabolic pathways and glucose metabolism.
Somayeh Pouriamehr, Haleh Barmaki, Mozhdeh Rastegary, Farzaneh Lotfi, Mohsen Nabi Afjadi   +4 more
doaj   +1 more source

Insulin-Like Growth Factor Receptor [PDF]

Journal of Thoracic Oncology, 2011
The insulin-like growth factor (IGF) signaling axis plays an essential role in the balance between cellular proliferation and apoptosis. Higher levels of IGF receptor are seen in lung tumor cells than normal tissue. IGF-1 receptor (IGFR-1R) and its ligand IGF-2 is overexpressed in non-small cell lung cancer (NSCLC).
openaire   +2 more sources

Glucokinase links Kruppel-like factor 6 to the regulation of hepatic insulin sensitivity in nonalcoholic fatty liver disease [PDF]

, 2011
The polymorphism, KLF6-IVS1-27A, in the Krüppel-like factor 6 (KLF6) transcription factor gene enhances its splicing into antagonistic isoforms and is associated with delayed histological progression of nonalcoholic fatty liver disease (NAFLD).
Gastaldelli, Amalia, Lee, Y., Isabel Fiel, Elisabetta Bugianesi, Miele, L., Lee, U., Bugianesi, E., Emma Buzzigoli, Andrea Mari, Pascoe, L., Mark Walker, Christopher P. Day, Burt, Alastair D., Walker, M., Bechmann, L., Hui, Kei Y, Fiel, I., Buzzigoli, E., Bechmann, Lars P., Miele, Luca, Fiel, Isabel., Luca Miele, Mari, Andrea, Patman, G., Ursula Muñoz, Day, Christopher P., Vetter, Diana., Burt, A., Lee, Young-Min., Munoz, Ursula., Hannivoort, Rebekka A., Alastair D. Burt, Amalia Gastaldelli, Walker, Mark., Agius, Loranne, Mari, A., Agius, Loranne., et al., Buzzigoli, Emma, Walker, Mark, Loranne Agius, Scott L. Friedman, Lee, Young-Min, Pascoe, Laura., Miele, Luca., Munoz, Ursula, Hui, K., Day, C., Laura Pascoe, Pascoe, Laura, Gastaldelli, Amalia., Fiel, Isabel, Ursula E. Lee, Gillian L. Patman, Munoz, U., Kei Y. Hui, Agius, L., Mari, Andrea., Vetter, D., Demetrio Ciociaro, Ciociaro, D., Buzzigoli, Emma., Lars P. Bechmann, Helen L. Reeves, Patman, Gillian L., Hannivoort, Rebekka A ., Ciociaro, Demetrio, Ciociaro, Demetrio., Mu?oz, Ursula, Bugianesi, Elisabetta, Diana Vetter, Reeves, Helen L., Hannivoort, R., Lee, Ursula E., Rebekka A. Hannivoort, Bugianesi, Elisabetta., Young-Min Lee, Vetter, Diana, Hui, Kei Y., Friedman, Scott L., Gastaldelli, A.   +80 more
core   +1 more source

Insulin-Like Growth Factor-1 and Neuroinflammation

Frontiers in Aging Neuroscience, 2017
Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia, Jose L. Labandeira-Garcia, Maria A. Costa-Besada, Maria A. Costa-Besada, Carmen M. Labandeira, Begoña Villar-Cheda, Begoña Villar-Cheda, Ana I. Rodríguez-Perez, Ana I. Rodríguez-Perez   +8 more
doaj   +1 more source

Insulin-Like Growth Factor Pathway and the Thyroid

Frontiers in Endocrinology, 2021
The insulin-like growth factor (IGF) pathway comprises two activating ligands (IGF-I and IGF-II), two cell-surface receptors (IGF-IR and IGF-IIR), six IGF binding proteins (IGFBP) and nine IGFBP related proteins.
Terry J. Smith
doaj   +1 more source