Insulin-like growth factor-II: new roles for an old actor
Frontiers in Endocrinology, 2012 IGF-II, traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator.
Stefano eCianfarani
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Insulin-Like Growth Factor Pathway and the Thyroid
Frontiers in Endocrinology, 2021 The insulin-like growth factor (IGF) pathway comprises two activating ligands (IGF-I and IGF-II), two cell-surface receptors (IGF-IR and IGF-IIR), six IGF binding proteins (IGFBP) and nine IGFBP related proteins.
Terry J. Smith
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Insulin-like Growth Factor 1 and Transforming Growth Factor-β Stimulate Cystine/Glutamate Exchange Activity in Dental Pulp Cells [PDF]
, 2011 Introduction The growth factors insulin-like growth factor (IGF-1) and transforming growth factor-β (TGF-β) are protective to dental pulp cells in culture against the toxicity of the composite materials Durafill VS and Flow Line (Henry Schein Inc, New ...
Alyssa Furey +39 more
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Antagonistic Autoantibodies to Insulin-Like Growth Factor-1 Receptor Associate with Poor Physical Strength [PDF]
, 2020 Natural autoantibodies to the IGF1 receptor (IGF1R-aAb) have been described in relation to Graves' ophthalmopathy. Other physiological roles of natural IGF1R-aAb are not known. We hypothesized that IGF1R-aAb may be related to muscle development.
Becker, Niels-Peter +7 more
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Insulin-like growth factors: Ligands, binding proteins, and receptors
Molecular Metabolism, 2021 Background: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in normal human physiology and disease states.
Derek LeRoith +2 more
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Insulin-Like Growth Factor-1 and Neuroinflammation
Frontiers in Aging Neuroscience, 2017 Insulin-like growth factor-1 (IGF-1) effects on aging and neurodegeneration is still controversial. However, it is widely admitted that IGF-1 is involved in the neuroinflammatory response.
Jose L. Labandeira-Garcia +8 more
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Insulin-like growth factor -I deficiency, insulin sensitivity, and glucose metabolism [PDF]
, 2013 In children and adolescents, growth hormone (GH) and insulin-like growth factor-I (IGF-I) act in concert to stimulate linear growth; however, the effects on glucose metabolism are in opposition. GH increases insulin resistance by lipolysis. In contrast,
Ekström, Klas
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Estudio inmunocitoquímico y molecular de cultivo primario de tejido molar
Biomédica: revista del Instituto Nacional de Salud, 2006 Introducción. La enfermedad trofoblástica gestacional comprende un conjunto de patologías caracterizadas por crecimiento e invasión anómalos del trofoblasto.
Yinth Andrea Bernal +6 more
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Nonlinear Evolution of Very Small Scale Cosmological Baryon Perturbations at Recombination [PDF]
Astrophys.J. 547 (2001) 1-11, 2000 The evolution of baryon density perturbations on very small scales is investigated. In particular, the nonlinear growth induced by the radiation drag force from the shear velocity field on larger scales during the recombination epoch, which is originally proposed by Shaviv in 1998, is studied in detail.
arxiv +1 more source
Influence of the growth gradient on surface wrinkling and pattern transition in growing tubular tissues [PDF]
, 2021 Growth-induced pattern formations in curved film-substrate structures have attracted extensive attentions recently. In most existing literature, the growth tensor is assumed to be homogeneous or piecewise homogeneous. In this paper, we aim at clarifying the influence of a growth gradient on pattern formation and pattern evolution in bilayered tubular ...
arxiv +1 more source