Results 221 to 230 of about 714,864 (392)

EGR1 Promotes Craniofacial Bone Regeneration via Activation of ALPL⁺PDGFD⁺ Periosteal Stem Cells

Advanced Science, EarlyView.
ALPL+PDGFD+ (AP+) cells are distinct calvarial periosteal stem cells (PeSCs) with diminished postnatal activity. EGR1 drives PeSCs development via BMP signaling through its Znf2 domain and activates them via CTNNB1/WNT10B signaling through its Znf2/3 domains.
Yang Li, Dazhuang Lu, Fanqing Xu, Jun Yang, Dong Li, Chenlong Yang, Xin Chen, Xu Wang, Jia Qing, Hui Zhang, Yingfei Zhang, Fuchou Tang, Jie Qiao, Ophir D. Klein, Ping Zhang, Yongsheng Zhou   +15 more
wiley   +1 more source

Roles of Insulin-Like Growth Factor-1 in Muscle Wasting and Osteopenia in Mice with Hyponatremia. [PDF]

Calcif Tissue Int
Kawao N, Nishikawa A, Matsumura D, Yamada A, Ohira T, Mizukami Y, Kaji H.   +6 more
europepmc   +1 more source

Clinicopathological significance of the gene expression of matrix metalloproteinase-7, insulin-like growth factor-1, insulin-like growth factor-2 and insulin-like growth factor-1 receptor in patients with colorectal cancer: Insulin-like growth factor-1 receptor gene expression is a useful predictor of liver metastasis from colorectal cancer

, 1994
Takashi Oshima
openalex   +2 more sources

Insulin-like growth factor-1 content and pattern of expression correlates with histopathologic grade in diffusely infiltrating astrocytomas [PDF]

, 1999
Hirofumi Hirano, M. Beatriz S. Lopes, Edward R. Laws, Tetsuhiko Asakura, Masamichi Goto, Joan E. Carpenter, Larry R. Karns, Scott R. VandenBerg   +7 more
openalex   +1 more source

The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges

Advanced Science, EarlyView.
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li, Ying Zhang, Zhenyu Xiao, Jieyu Qi   +3 more
wiley   +1 more source

DNA‐PKcs‐Driven YAP1 Phosphorylation and Nuclear Translocation: a Key Regulator of Ferroptosis in Hyperglycemia‐Induced Cardiac Dysfunction in Type 1 Diabetes

Advanced Science, EarlyView.
In the context of chronic hyperglycemia, a DDR is initiated, leading to the pathological activation of DNA‐PKcs in the diabetic heart. This activated DNA‐PKcs directly interacts with and phosphorylates YAP1 at Thr226, thereby increasing the nuclear expression of YAP1.
Junyan Wang, Xing Chang, Chun Li, Jing Gao, Zhijiang Guo, Haowen Zhuang, Lingjun Wang, Yusheng Huang, Wei Wang, Chao Li, Qingyong He   +10 more
wiley   +1 more source

Mutants of human insulin-like growth factor II with altered affinities for the type 1 and type 2 insulin-like growth factor receptor.

, 1991
Daniel Bürgisser, Birgit Roth, Roman J. Giger, Christine Lüthi, S Weigl, Jürg A. Zarn, R Humbel   +6 more
openalex   +1 more source

Association of insulin-like growth factor 1 and metabolic parameters with mild subclinical hypothyroidism in obese boys. [PDF]

Sci Rep
Xue J, Li C, Ju J, Liang S.
europepmc   +1 more source

Insulin-like Growth Factor-Binding Protein-1, A Marker of Insulin Production

, 1993
Kerstin Hall, Kerstin Brismar, Agneta Hilding, Björn F. Lindgren   +3 more
openalex   +2 more sources

Tyrosine Kinases Expressed in Vivo by Human Prostate Cancer Bone Marrow Metastases and Loss of the Type 1 Insulin-Like Growth Factor Receptor [PDF]

, 1999
Andreas Chott, Zijie Sun, Daniel Morganstern, Jing Pan, Tong Li, Martin Susani, Isabella Mosberger, Melissa P. Upton, Glenn J. Bubley, Steven P. Balk   +9 more
openalex   +1 more source