Results 251 to 260 of about 714,864 (392)

Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy

Advanced Science, EarlyView.
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Christopher Li, Yueming Zhu, Mengyuan Zhang, Xiaodong Lu, Nagendra S. Yarla, Lu Wang, Jindan Yu, Jonathan C. Zhao, Ivet Bahar, Yong Wan   +14 more
wiley   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Association of serum insulin-like growth factor-1 and adrenocorticotropic hormone therapeutic response in patients with infantile epileptic spasms syndrome. [PDF]

Front Pharmacol
Lin KN, Han F, Wang YY, Zhao W, Wang JW, Li H, Zhou YQ.   +6 more
europepmc   +1 more source

Serum High Molecular Weight Form of Insulin-Like Growth Factor II from Patients with Non-Islet Cell Tumor Hypoglycemia Is O-Glycosylated¹ [PDF]

, 1998
Naomi Hizuka, Izumi Fukuda, Kazue Takano, Kumiko Asakawa‐Yasumoto, Yumiko Okubo, Hiroshi Demura   +5 more
openalex   +1 more source

Platelet-Secreted MicroRNA-223 Promotes Endothelial Cell Apoptosis Induced by Advanced Glycation End Products via Targeting the Insulin-like Growth Factor 1 Receptor

Journal of Immunology, 2014
Yi Pan, Hongwei Liang, Huanling Liu, Donghai Li, Xi Chen, Limin Li, Chen-Yu Zhang, Ke Zen   +7 more
semanticscholar   +1 more source

Vascular Disease and Insulin-Like Growth Factor-1

Vascular Disease Prevention, 2007
Georgios Efstratiadis, Georgios Tsiaousis, Vasilios G. Athyros   +2 more
openaire   +2 more sources

Optogenetic‐Controlled iPSC‐Based Vaccines for Prophylactic and Therapeutic Tumor Suppression in Mice

Advanced Science, EarlyView.
This study develops an a red/far‐red light‐controlled iPSC‐based vaccines (RIVA) based on the chimeric photosensory protein FnBphP and its interaction partner LDB3 for cancer immunotherapy. The RIVA preserves the multiple intrinsic tumor antigens of iPSCs and enables optogenetic control of the expression of the immune adjuvant type I interferon β under
Longliang Qiao, Lingxue Niu, Zhihao Wang, Di Dai, Shasha Tang, Xiaoding Ma, Zhenqiang Deng, Guiling Yu, Yang Zhou, Tao Yan, Xingwan Liu, Deqiang Kong, Linfeng Hu, Xiang Li, Junwei Zhao, Fengfeng Cai, Meiyan Wang, Haifeng Ye   +17 more
wiley   +1 more source

Biological applications on a novel composite hydrogel containing mesoporous silica nanoparticles loaded with insulin-like growth Factor-1 and Vancomycin. [PDF]

J Mater Sci Mater Med
Ren H, Guo Q, Lin B, Liu Y, Wang X, Huang K, Wu K.   +6 more
europepmc   +1 more source

Influence of Circulating Epinephrine and Norepinephrine on Insulin-Like Growth Factor Binding Protein-1 in Humans [PDF]

, 1997
E. Fernqvist‐Forbes, Agneta Hilding, Karin Ekberg, Kerstin Brismar   +3 more
openalex   +1 more source

Insulin-like Growth Factor 1 Signaling Axis Meets p53 Genome Protection Pathways [PDF]

, 2016
Derek LeRoith, Haim Werner, Ilan Bruchim, Rive Sarfstein   +3 more
core   +1 more source