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Vertex balding, plasma insulin-like growth factor 1, and insulin-like growth factor binding protein 3

Journal of the American Academy of Dermatology, 2000
A recent report suggested that men with vertex balding have higher levels of plasma insulin-like growth factor 1 (IGF-1). The association of its major carrier protein, insulin-like growth factor binding protein 3 (IGFBP-3), with male pattern hair loss has not been examined.We evaluated the relations of plasma concentrations of IGF-1 and IGFBP-3 with ...
E A, Platz   +3 more
openaire   +2 more sources

Insulin-Like Growth Factor 1 Expression in Thyroid Tumors

Applied Immunohistochemistry & Molecular Morphology, 2000
Insulin-like growth factor 1 (IGF-1) likely is involved in thyrocyte proliferation via autocrine mechanisms, but limited data are available on its in vivo expression in thyroid neoplasms. This prompted us to explore IGF-1 expression at the protein and mRNA levels and IGF-1 receptor (IGF-1rec) immunoreactivity in normal and neoplastic thyroids (50 ...
Maiorano E   +7 more
openaire   +4 more sources

Insulin-like Growth Factor-1 Deficiency

2019
Since insulin-like growth factor-1 (IGF-1) measurement has become widely known to reflect cumulative growth hormone (GH) secretion, it is not surprising for clinicians to be tempted to use IGF-1 levels to not only screen for GH excess but for GH deficiency also (Le Roith D. Seminars in medicine of the Beth Israel Deaconess Medical Center.
Thomas Ittoop, S. Sethu K. Reddy
openaire   +1 more source

Serum Levels of Insulin-like Growth Factor-1 and Insulin-like Growth Factor-1 Binding Proteins After Radical Prostatectomy

Journal of Urology, 2002
Elevated serum levels of insulin-like growth factor-1 (IGF-1) have been consistently shown to be a risk factor for prostate cancer. Alterations in serum IGF-1 binding proteins 1 to 3 have also been associated with prostate cancer risk. A potentially important complication in these studies is that prostate tissue, perhaps especially malignant prostate ...
Glenn J, Bubley   +7 more
openaire   +2 more sources

Expression of insulin-like growth factor-1 and insulin-like growth factor-1 receptors in EL4 lymphoma cells overexpressing growth hormone

Cellular Immunology, 2005
Almost all of the previous studies with growth hormone (GH) have been done with exogenously supplied GH and, therefore, involve actions of the hormone through its receptor. However, the actions of endogenous or lymphocyte GH are still unclear. In a previous study, we showed that overexpression of GH (GHo) in a lymphoid cell line resulted in protection ...
Douglas A, Weigent, Robyn E, Arnold
openaire   +2 more sources

Serum Insulin-Like Growth Factor Type 1, Insulin-Like Growth Factor-Binding Protein-1, and Insulin-Like Growth Factor-Binding Protein-3 Concentrations in Patients with Thyroid Dysfunction

Thyroid, 2001
Thyroid hormones play a role in the regulation of insulin-like growth factor type 1 (IGF-1) and insulin-like growth factor-binding protein-3 (IGFBP-3) expression, and both IGF-1 and IGFBPs have been shown to be related to the function and growth of the thyroid. Our aim was to evaluate serum concentrations of IGF-1, IGFBP-1, and IGFBP-3 in patients with
P, Iglesias   +5 more
openaire   +2 more sources

Glucose Metabolism, Insulin-like Growth Factor-I, and Insulin-like Growth Factor-Binding Protein-1 After Alcohol Withdrawal

Alcoholism: Clinical & Experimental Research, 1999
Alcohol abusers often present with deteriorated glucose metabolism and insulin resistance. Changes in other glucoregulators, such as insulin‐like growth factor‐I (IGF‐I) and IGF‐binding protein‐1 (IGFBP‐1) may also be related to alcohol abuse. We studied the effects of alcohol withdrawal on blood glucose, serum insulin and C‐peptide, and plasma IGF‐I ...
M, Passilta   +2 more
openaire   +2 more sources

Testosterone increases insulin-like growth factor-1 and insulin-like growth factor-binding protein.

Annals of clinical and laboratory science, 1995
Growth of the male external genitalia is primarily regulated by androgens; however, several observations suggest growth hormone (GH) or a GH dependent factor, such as insulin-like growth factor-1 (IGF-1), might also be involved. It is hypothesized that testosterone (T) might induce the synthesis of IGF-1 or IGF-binding protein (IGF-BP) which could ...
W S, Ashton   +3 more
openaire   +1 more source

INSULIN-LIKE GROWTH FACTOR 1 (IGF-1) ANTLER-STIMULATING HORMONE?

Endocrinology, 1985
We have investigated the possibility that IGF-1 may play a role in the regulation of antler development. Plasma IGF-1 concentrations were measured throughout the first period of development of the pedicle and first antler of red deer (Cervus elaphus) to determine whether a relationship existed between growth of antler cartilage (velvet antler) and IGF ...
J M, Suttie   +5 more
openaire   +2 more sources

Insulin-like growth factor 1 (IGF-1) in burn patients

Burns, 1991
Variations in growth factor IGF-1 levels during wound healing were assessed in 23 patients with burns of varying extent and severity. The patients were followed during the postburn period and the IGF-1 levels were regularly measured by radioimmunoassay.
S, Møller   +3 more
openaire   +2 more sources

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