Results 21 to 30 of about 242,633 (111)

IGF-1 and IGFBP3 as indirect markers of hepatic insulin resistance and their relation to metabolic syndrome parameters in liver steatosis patients

Endocrine Regulations, 2023
Objective. The aim of the present study was to assess insulin-like growth factor 1 (IGF-1) and IGF-binding protein 3 (IGFBP3) as markers of insulin resistance in patients with prediabetes and type 2 diabetes mellitus (TDM2).
Fraenkel Emil, Lazurova Ivica
doaj   +1 more source

Insulin like growth factor 2 mRNA binding protein 2 regulates vascular development in cerebral arteriovenous malformations

Frontiers in Neurology
BackgroundCerebral arteriovenous malformations (AVMs) are intricate vascular anomalies that disrupt normal cerebral blood flow, potentially leading to severe neurological complications.
Lin-jian Wang, Lin-jian Wang, Lin-jian Wang, Yangyang Wu, Yangyang Wu, Yangyang Wu, Sha Xie, Hongkai Lian, Hongkai Lian, Hongkai Lian   +9 more
doaj   +1 more source

Insulin-Like Growth Factor-I Axis Changes in Fasting Among Healthy and Prediabetic Men: A Case-Control Study

Endocrinology Research and Practice, 2023
Objective: Energy deprivation induces changes in various components of the “growth hormone”/“insul in-like growth factor-I” axis; however, it remains unclear whether Ramadan fasting could alter which ones in response to food deprivation.
Majid Reza Sheikh Rezaee, Saeid Abediankenari, Parisa Islami Parkoohi, Fatemeh Daneshvar, Ahmad Ahmadzadeh Amiri   +4 more
doaj  

The impact of circulating IGF-1 and IGFBP-2 on cardiovascular prognosis in patients with acute coronary syndrome

Frontiers in Cardiovascular Medicine, 2023
BackgroundWhile insulin-like growth factor 1 (IGF-1) exerts a cardioprotective effect in the setting of atherosclerosis, insulin-like growth factor binding protein 2 (IGFBP-2) is involved in metabolic syndrome.
Wei Wang, Wei Wang, Kang Yu, Shou-Yong Zhao, De-Gang Mo, Jia-Hui Liu, Li-Jinn Han, Tai Li, Heng-Chen Yao, Heng-Chen Yao   +9 more
doaj   +1 more source

Linear growth failure induced by systemic inflammation inhibiting IGF-1/IGFBP axis in rats with asymptomatic colitis

BMC Gastroenterology, 2019
Background Children in poor areas show significant growth retardation that does not improve with an adequate supply of energy and nutrients, which may be related to asymptomatic intestinal infection caused by poor sanitation. Our objective was to explore
Xiaoyang Sheng, Xueqing Sun, Feng Li, Junli Wang, Jingqiu Ma   +4 more
doaj   +1 more source

Effect of IGFBP2 Overexpression on the Expression of Fatty Acid Synthesis Genes in Primary Cultured Chicken Hepatocytes

The Journal of Poultry Science, 2019
The effects of insulin-like growth factor binding protein 2 (IGFBP2) on the expression of fatty acid synthesis regulators and triglyceride production were investigated in primary cultured chicken hepatocytes.
Yanshuang Mu, Yuhang Sun, Li Leng, Zhiping Cao, Yumao Li, Hui Li, Yuxiang Wang   +6 more
doaj   +1 more source

The Regulatory Role of Apelin on the Appetite and Growth of Common Carp (Cyprinus Carpio L.)

Animals, 2020
Apelin, a kind of active polypeptide, has many biological functions, such as promoting food intake, enhancing immunity, and regulating energy balance. In mammals, studies have indicated that apelin is involved in regulating food intake.
Xiao Yan, Chaobin Qin, Guokun Yang, Dapeng Deng, Liping Yang, Junchang Feng, Jiali Mi, Guoxing Nie   +7 more
doaj   +1 more source

IGF2 mRNA binding protein-2 is a tumor promoter that drives cancer proliferation through its client mRNAs IGF2 and HMGA1

eLife, 2017
The gene encoding the Insulin-like Growth Factor 2 mRNA binding protein 2/IMP2 is amplified and overexpressed in many human cancers, accompanied by a poorer prognosis.
Ning Dai, Fei Ji, Jason Wright, Liliana Minichiello, Ruslan Sadreyev, Joseph Avruch   +5 more
doaj   +1 more source

Imp-L2, a putative homolog of vertebrate IGF-binding protein 7, counteracts insulin signaling in Drosophila and is essential for starvation resistance

Journal of Biology, 2008
Background Insulin and insulin-like growth factors (IGFs) signal through a highly conserved pathway and control growth and metabolism in both vertebrates and invertebrates.
Honegger Basil, Galic Milos, Köhler Katja, Wittwer Franz, Brogiolo Walter, Hafen Ernst, Stocker Hugo   +6 more
doaj   +1 more source

Nutritional condition and IGF-1 and IGFBP-2 serum concentrations in students aged 7 to 9 attending two educational institutions

Revista de la Facultad de Medicina, 2016
Introduction: Nutritional vulnerability is more evident during childhood, since malnutrition has an impact on academic performance and is linked to different diseases during this period. Likewise, an increase in the incidence and prevalence of obesity in
Jenifer Tatiana Figueroa, Sorany Vera, Luz Helena Aranzález, Ismena Mockus   +3 more
doaj   +1 more source