Results 41 to 50 of about 242,633 (111)

Investigation of Insulin-Like Growth Factor 2 mRNA Binding Protein 2 Gene Polymorphisms in Type 2 Diabetes Patients

Genel Tıp Dergisi
Background/Aims: Type 2 diabetes (T2D) whose prevalance differs in different populations is a multifactorial disease. T2D is describes a group of clinical syndromes resulting from glucose metabolism disorders triggered by genetic
Duygu Yolal Ertural, Ümit Çınkır, Nurcan Aras   +2 more
doaj   +1 more source

No evidence that human GIGYF2 interacts with GRB10: implications for human disease

Life Science Alliance
Human GRB10 protein, unlike its mouse counterpart, lacks a PPGΦ motif and cannot bind to GIGYF2. These findings question the published literature that links GRB10/GIGYF2 binding to human disease.
Jung-Hyun Choi, Israel Shpilman, Niaz Mahmood, Shaghayegh Farhangmehr, Ulrich Braunschweig, Nathalia Gomide Cruz, Jun Luo, Reese Jalal Ladak, Angelos Pistofidis, Jiannis Ragoussis, T Martin Schmeing, Seyed Mehdi Jafarnejad, Benjamin J Blencowe, Nahum Sonenberg   +13 more
doaj   +1 more source

Overexpression of insulin-like growth factor-2 mRNA-binding protein 1 is associated with periodontal disease

Journal of Oral Biology and Craniofacial Research
Objective: To investigate the potential role of a novel m6A RNA regulator, Insulin-like Growth Factor-2 mRNA-binding protein 1 (IGF2BP1), in periodontal disease pathogenesis.
Burra Anand Deepika, Jaiganesh Ramamurthy, Balachander Kannan, Vijayashree Priyadharsini Jayaseelan, Paramasivam Arumugam   +4 more
doaj   +1 more source

Plasma Insulin-like Growth Factor-Binding Protein-2 of Critically Ill Patients Is Related to Disease Severity and Survival. [PDF]

Biomedicines, 2023
Mester P, Räth U, Popp L, Schmid S, Müller M, Buechler C, Pavel V.   +6 more
europepmc   +1 more source

Insulin-like growth factor-2 mRNA-binding protein 2 facilitates post-ischemic angiogenesis by increasing the stability of fibroblast growth factor 2 mRNA and its protein expression

Heliyon
Background: Post-ischemic angiogenesis is crucial for reestablishing blood flow in conditions such as peripheral artery disease (PAD). The role of insulin-like growth factor-2 mRNA-binding protein 2 (IGF2BP2) in post-transcriptional RNA metabolism and ...
Shuai Ma, Yiqing Hu, Wangguo Xu, Weidong Xiong, Xinyu Xu, Yajie Hou, Ying Wang, Panke Chen, Wenbi Yang, Hao Lu, Yongchao Zhao   +10 more
doaj   +1 more source

Serum insulin-like growth factor-binding protein 2 levels as an indicator for disease severity in enterohemorrhagic Escherichia coli induced hemolytic uremic syndrome. [PDF]

Ren Fail, 2021
Tasaki Y, Inoue N, Shimizu M, Sugimoto N, Ishikawa S, Mizuta M, Yokoyama T, Kuroda M, Ohta K, Yachie A, Wada T.   +10 more
europepmc   +1 more source

Glucose-dependent control of insulin like growth factor 2 mRNA binding protein 2 and other gene expressions in ERN1 knockdown glioblastoma cells

Endocrine Regulations
Objective. Endoplasmic reticulum stress and glucose supply are significant factors in glioblastoma growth. The present study aims to investigate the impact of glucose-dependent control of IGF2BP2, TOB1, HBEGF, TWIST1, CCNH, and E2F1 gene expression in ...
Minchenko Oleksandr H., Viletska Yuliia M., Sliusar Myroslava Y., Hnatiuk Oksana S., Ratushna Oksana O., Feldman Taia V., Kozynkevych Halyna E., Bezrodnyi Borys H., Minchenko Dmytro O.   +8 more
doaj   +1 more source

Insulin-like Growth Factor Binding Protein-2 (IGFBP2) Is a Key Molecule in the MACC1-Mediated Platelet Communication and Metastasis of Colorectal Cancer Cells. [PDF]

Int J Mol Sci, 2021
Haschemi R, Kobelt D, Steinwarz E, Schlesinger M, Stein U, Bendas G.   +5 more
europepmc   +1 more source

circSMARCA5 Is an Upstream Regulator of the Expression of miR-126-3p, miR-515-5p, and Their mRNA Targets, Insulin-like Growth Factor Binding Protein 2 (IGFBP2) and NRAS Proto-Oncogene, GTPase (NRAS) in Glioblastoma. [PDF]

Int J Mol Sci, 2022
Merulla AE, Stella M, Barbagallo C, Battaglia R, Caponnetto A, Broggi G, Altieri R, Certo F, Caltabiano R, Ragusa M, Barbagallo GMV, Di Pietro C, Purrello M, Barbagallo D.   +13 more
europepmc   +1 more source

Significant association between insulin-like growth factor 2 mRNA-binding protein 2, interleukin-6 polymorphisms, and type 2 diabetes mellitus

Journal of Research in Medical Sciences
Background: The study aimed to detect the association between insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) and interleukin-6 (IL-6) polymorphisms among type 2 diabetes mellitus (T2DM).
Elmutuz H Elssaig, Eltayib H Ahmed-Abakur, Tarig M S Alnour, Mohamed A. Alsubai, Aadil Yousif   +4 more
doaj   +1 more source