Results 271 to 280 of about 410,191 (299)

Insulin-like Growth Factor Binding Protein 3 in Inflammatory Bowel Disease

Digestive Diseases and Sciences, 2005
Epithelial cell growth regulation has been reported to be altered in inflammatory bowel disease (IBD) patients. The cell growth regulatory factor, insulin-like growth factor binding protein 3 (IGFBP-3), may be partly responsible for this phenomenon. So far, IGFBP-3 levels have been assessed as values of total protein, which is a sum of bioactive intact
Kirman, Irena, Whelan, Richard Larry, Jain, Suvinit, Nielsen, Sara Elsøe, Seidelin, Jakob Benedict, Nielsen, Ole Haagen   +5 more
openaire   +2 more sources

Insulin-Like Growth Factor Binding Protein-3 Inhibits Colitis-Induced Carcinogenesis

Diseases of the Colon & Rectum, 2007
Chronic inflammation in the setting of inflammatory bowel disease is thought to result in altered epithelial cell growth regulation and ultimately carcinogenesis. This loss in cell growth regulation may be partially caused by a decrease in circulating intact insulin-like growth factor binding protein-3 (IFGB-3) as a result of chronic inflammation. This
A, Belizon, E, Balik, I, Kirman, H, Remotti, N, Ciau, S, Jain, R L, Whelan   +6 more
openaire   +2 more sources

PROTEINS IN TISSUE EXTRACTS WHICH BIND INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN-3 (IGFBP-3)

Journal of Endocrinology, 1995
ABSTRACT Membrane associated IGFBP-3 is now known to play a role in the modulation of IGF at the cellular level, but mechanisms involved in cell membrane binding are far from certain. In this study we report the identification and initial structural characterisation of proteins in a range of sheep and rat tissues which specifically bind ...
S, Hodgkinson, P, Fowke, N, al Somai, M, McQuoid   +3 more
openaire   +2 more sources

High-affinity growth hormone binding protein, insulin-like growth factor I and insulin-like growth factor binding protein 3 in adults with growth hormone deficiency

European Journal of Endocrinology, 1996
Roelen CA, Koppeschaar HP, de Vries WR, Zelissen PM, Snel YE, Doerga ME, Thijssen JH, Blankenstein RA. High-affinity growth hormone binding protein, insulin-like growth factor I and insulin-like growth factor binding protein 3 in adults with growth hormone deficiency. Eur J Endocrinol 1996;135:82–6.
C A, Roelen, H P, Koppeschaar, W R, de Vries, P M, Zelissen, Y E, Snel, M E, Doerga, J H, Thijssen, R A, Blankenstein   +7 more
openaire   +2 more sources

Serum Free and Total Insulin-Like Growth Factor-I, Insulin-Like Growth Factor Binding Protein-1 and Insulin-Like Growth Factor Binding Protein-3Levels in Healthy Elderly Individuals

Gerontology, 1998
<b>Background:</b> Little is known about the influence of the free insulin-like growth factor-I/insulin-like growth factor binding protein (IGF-I/IGFBP) system on the quality of health and on disability in the elderly population. <b>Design:</b> In a cross-sectional population based study of 218 healthy elderly subjects (age 55 ...
Janssen, J.A.M.J.L., Stolk, RP (Ronald), Pols, Huib, Grobbee, DE, Lamberts, S.W.J.   +4 more
openaire   +2 more sources

Regulation and Actions of Insulin-Like Growth Factor Binding Protein-3

1991
Binding proteins for the insulin-like growth factors (IGFs), first described 15 years ago, are now recognized as playing important roles as carriers of IGFs in the circulation, and modulators of IGF actions on target cells 1. Three distinct structural classes of IGF binding protein (IGFBP) have been identified on the basis of cDNA cloning 2–6, and at ...
R C, Baxter, J L, Martin
openaire   +2 more sources

Cancer treatment and survivorship statistics, 2022

Ca-A Cancer Journal for Clinicians, 2022
Kimberly D Miller, Leticia M Nogueira, Angela B Mariotto   +2 more
exaly  

Systemic therapy for hormone receptor‐positive/human epidermal growth factor receptor 2‐negative early stage and metastatic breast cancer

Ca-A Cancer Journal for Clinicians, 2023
Laura A Huppert, Hope S Rugo
exaly  

Current treatment and recent progress in gastric cancer

Ca-A Cancer Journal for Clinicians, 2021
Smita S Joshi, Brian D Badgwell
exaly  

Treatment of muscle‐invasive and advanced bladder cancer in 2020

Ca-A Cancer Journal for Clinicians, 2020
Vaibhav G Patel, William K Oh, Matthew D Galsky   +2 more
exaly