Results 41 to 50 of about 499,115 (339)

Role of Insulin-like Growth Factor Binding Protein 3 as a Diagnostic Marker of Growth Hormone in Patients with Acromegaly

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2013
The paper studied the levels IGFBP-3 in patients with acromegaly, received different therapies. The findings showed that patients with acromegaly after surgical removal of a pituitary tumor, as well as after radiation therapy, the most sensitive ...
A.O. Kholikova
doaj   +1 more source

Malnutrition in children associated with low insulin-like growth factor binding protein-3 (IGFBP-3) levels

open access: yesGaceta Sanitaria, 2021
Objective: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status.
Dwi Ayu Rahmawati   +5 more
doaj   +1 more source

IGFBP-3 inhibits Wnt signaling in metastatic melanoma cells. [PDF]

open access: yes, 2016
In previous works, we have shown that insulin-like growth factor-binding protein-3 (IGFBP-3), a tissue and circulating protein able to bind to IGFs, decreases drastically in the blood serum of patients with diffuse metastatic melanoma.
Londei, Paola   +7 more
core   +1 more source

Short hairpin RNA targeting insulin-like growth factor binding protein-3 restores the bioavailability of insulin-like growth factor-1 in diabetic rats

open access: yesInternational Brazilian Journal of Urology, 2016
Purpose To investigate whether intracavernosal injection of short hairpin RNA for IGFBP-3 could improve erectile function in streptozotocin-induced diabetic rats.
Zhang-Yan Zhou   +10 more
doaj   +1 more source

Role of insulin-like growth factor binding protein-3 in 1, 25-dihydroxyvitamin-d 3 -induced breast cancer cell apoptosis. [PDF]

open access: yes, 2013
Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells.
Brosseau, C, Colston, KW, Pirianov, G
core   +2 more sources

Cellular Internalization of Insulin-like Growth Factor Binding Protein-3

open access: yesJournal of Biological Chemistry, 2004
Insulin-like growth factor binding protein-3 (IGFBP-3) is well established as a growth-inhibitory, apoptosis-inducing secreted molecule that acts via insulin-like growth factor (IGF)-independent as well as IGF-dependent pathways.
Kuk-Wha Lee   +6 more
semanticscholar   +1 more source

Preoperative insulin-like growth factor-binding protein-3 (IGFBP-3) blood level predicts gleason sum upgrading [PDF]

open access: yes, 2012
In this study, we evaluated the ability of preoperative IGFBP-2, IGFBP-3, IL-6, and SIL-6R serum levels to predict Gleason score upgrade in 52 PCa ...
Altieri V   +8 more
core   +1 more source

Insulin-like growth factor 1 and insulin-like growth factor binding protein-3 as predictive biomarkers of depression and migraine in obese women

open access: yesThe Egyptian Journal of Internal Medicine, 2019
Introduction Obesity and its comorbidity, depression and migraine, are highly prevalent conditions and public health problems of enormous scope that are responsible for the significant quality of life impairment and financial cost.
Nearmeen M Rashad   +4 more
doaj   +1 more source

Micro RNA 145 targets the insulin receptor substrate-1 and inhibits the growth of colon cancer cells [PDF]

open access: yes, 2007
The insulin receptor substrate-1 (IRS-1), a docking protein for both the type 1 insulin-like growth factor receptor (IGF-IR) and the insulin receptor, is known to send a mitogenic, anti-apoptotic, and anti-differentiation signal. Several micro RNAs (miRs)
Baserga, Renato   +5 more
core   +2 more sources

Consequences of Postnatally Elevated Insulin-Like Growth Factor-II in Transgenic Mice: Endocrine Changes and Effects on Body and Organ Growth. [PDF]

open access: yes, 1994
Insulin-like growth factor-II (IGF-II) is an important regulator of embryonic growth and differentiation, but its function in postnatal life is unclear. To address this point, we generated transgenic mice harboring fusion genes in which a human IGF-II
Blum, Werner F.   +4 more
core   +1 more source

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