Results 81 to 90 of about 103,750,445 (281)
Endocrine Connections, 2018 The growth hormone (GH)–insulin-like growth factor (IGF)-I axis is a key endocrine mechanism regulating linear growth in children. While paediatricians have a good knowledge of GH secretion and assessment, understanding and use of measurements of the ...
Werner F Blum +6 more
doaj +1 more source
Associations of insulin‐like growth factor and insulin‐like growth factor binding protein‐3 with mortality in women with breast cancer [PDF]
International Journal of Cancer, 2012 AbstractElevated circulating insulin‐like growth factor‐1 (IGF‐1), a breast epithelial cell mitogen, is associated with breast cancer development. However, its association with breast cancer survival is not established. Circulating concentrations of IGF‐1 are controlledviabinding proteins, including IGF Binding Protein‐3 (IGFBP‐3), that may modulate ...
Catherine, Duggan +10 more
openaire +2 more sources
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
International Journal of Endocrinology, 2017 Aim. Insulin-like growth factor-1 (IGF-1) is a potent mitogen for many cells. IGF-1 plays a role in the pathogenesis of various tumors with its mutagenic and antiapoptotic properties. The aim of this study was to determine both the serum and intranodular
Ayfer Altas +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.Versatile guanosine‐quadruplex (GQ) hydrogels are developed as dynamic biomatrices for cell culture. These scaffolds are fabricated under mild aqueous conditions, present improved stability, tunable mechanical properties within physiological ranges; fibrillar, porous microstructure, ion conductivity, and cytocompatibility.
Neha Thakur +10 more
wiley +1 more source
Biodegradable Conductors for Implantable and Wearable Transient Bioelectronics
Advanced Functional Materials, EarlyView.Biodegradable conductors are essential building blocks for transient bioelectronics, enabling temporary sensing, stimulation, and energy transfer while eliminating the need for device retrieval. This review summarizes biodegradable metals, conducting polymers, ionic conductors, and conductive composites, highlighting degradation mechanisms, material ...
Yicheng Zhu, Yijun Liu, Naoji Matsuhisa
wiley +1 more source
International Brazilian Journal of Urology, 2015 Introduction Non-androgenic growth factors are involved in the growth regulation of prostate cancer (PCa). Objective This is the first Brazilian study to correlate, in a population of patients operated for PCa, PSA, total testosterone, insulin-like ...
Lívia L. Corrêa +5 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez +12 more
wiley +1 more source
Insulin-like growth factor binding protein-3 in preterm infants with retinopathy of prematurity
Indian Journal of Ophthalmology, 2012 Background: Retinopathy of prematurity (ROP) is the main cause of visual impairment in preterm newborn infants. Objective: This study was conducted to determine whether insulin-like growth factor binding protein -3 (IGFBP-3) is associated with ...
Manizheh Mostafa Gharehbaghi +3 more
doaj +1 more source
IGF-independent effects of insulin-like growth factor binding protein-5 (Igfbp5) in vivo
, 2009 IGF activity is regulated tightly by a family of IGF binding proteins (IGFBPs). IGFBP-5 is the most conserved of these and is up-regulated significantly during differentiation of several key lineages and in some cancers.
Pell, J. M. +11 more
core +1 more source