Results 1 to 10 of about 361,829 (151)

Insulin-Like Growth Factor Binding Proteins in Kidney Disease [PDF]

Frontiers in Pharmacology, 2021
The seven members of the insulin-like growth factor (IGF) binding protein family (IGFBPs) were initially considered to be the regulatory proteins of IGFs in the blood circulation, mainly as the subsequent reserve for bidirectional regulation of IGF ...
Shuqiang Wang, Shuqiang Wang, Kun Chi, Di Wu, Quan Hong   +4 more
doaj   +2 more sources

Insulin-Like Growth Factor Binding Proteins in Autoimmune Diseases [PDF]

Frontiers in Endocrinology, 2018
Insulin-like growth factor binding proteins (IGFBPs) are a family of proteins binding to Insulin-like growth factors (IGFs), generally including IGFBP1, IGFBP2, IGFBP3, IGFBP4, IGFBP5, and IGFBP6.
Huihua Ding, Tianfu Wu
doaj   +2 more sources

Insulin-Like Growth Factor-Binding Proteins of Teleost Fishes [PDF]

Frontiers in Endocrinology, 2018
The insulin-like growth factor (Igf) binding protein (Igfbp) family has a broad range of physiological functions and a fascinating evolutionary history. This review focuses on the Igfbps of teleost fishes, where genome duplication events have diversified
Daniel Garcia de la Serrana, Daniel J. Macqueen   +1 more
doaj   +2 more sources

Proteomics discovery of pulmonary hypertension biomarkers: Insulin‐like growth factor binding proteins are associated with disease severity [PDF]

Pulmonary Circulation, 2022
Pulmonary arterial hypertension (PAH) is a progressive disease characterized by sustained elevations of pulmonary artery pressure. To date, we lack circulating, diagnostic, and prognostic markers that correlate to clinical and functional parameters.
Melanie K. Nies, Jun Yang, Megan Griffiths, Rachel Damico, Jie Zhu, Dhananjay Vaydia, Zongming Fu, Stephanie Brandal, Eric D. Austin, Dunbar D. Ivy, Paul M. Hassoun, Jennifer E. Van Eyk, Allen D. Everett   +12 more
doaj   +2 more sources

Insulin-like growth factor binding proteins: a structural perspective [PDF]

Frontiers in Endocrinology, 2012
Insulin-like growth factor binding proteins (IGFBP-1 to -6) bind insulin-like growth factors-I and -II (IGF-I and IGF-II) with high affinity. These binding proteins maintain IGFs in the circulation and direct them to target tissues, where they promote ...
Briony eForbes, Peter eMcCarthy, Raymond eNorton   +2 more
doaj   +2 more sources

Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients [PDF]

BMC Research Notes, 2019
Objective The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are thought to play a significant role in metabolic pathways and glucose metabolism.
Somayeh Pouriamehr, Haleh Barmaki, Mozhdeh Rastegary, Farzaneh Lotfi, Mohsen Nabi Afjadi   +4 more
doaj   +2 more sources

Pan‐cancer analysis of oncogenic role of insulin‐like growth factor‐binding proteins and validation in ovarian cancer [PDF]

Cancer Medicine, 2023
Background Numerous studies have shown that the insulin‐like growth factor (IGF) pathway is highly associated with tumor initial and progression in several tumors.
Wei Tan, Jie Zhang, Zhimin Deng, Fangfang Dai, Lujia Tang, Wei Hu, Hua Liu   +6 more
doaj   +2 more sources

Role of insulin-like growth factor, insulin-like growth factor receptors, and insulin-like growth factor-binding proteins in ovarian cancer

Indian Journal of Medical and Paediatric Oncology, 2017
Insulin and IGFs play an important role in cancer initiation and progression, including ovarian cancer (OC). Epithelial ovarian cancer (EOC) is the most frequent type of OC in women and it is the most lethal gynecological malignancy worldwide. Generally,
Periyasamy Amutha, Thangarajan Rajkumar
doaj   +2 more sources

Association between serum levels of insulin-like growth factor-binding proteins at admission and outcomes at 3 months after acute ischemic stroke [PDF]

Annals of Medicine
Background Insulin-like growth factor-binding proteins (IGFBPs) contribute to central nervous system development and may influence recovery after stroke.
Yuyi Zhu, Huan Wang, Ting Cui, Mingxi Chen, Yaqi Chen, Simiao Wu, Zilong Hao, Shihong Zhang, Xinyi Leng, Deren Wang   +9 more
doaj   +2 more sources

Effectiveness of low-fat diet on the levels of insulin-like growth factor-1 and insulin-like growth factor binding proteins: a systematic review and meta-analysis of randomized controlled clinical trials [PDF]

Journal of Health, Population and Nutrition
Background Previous researches on the effect of low-fat diet (LF) on insulin-like growth factor-1 (IGF-1), and its binding proteins (IGFBPs) did not reach a consensus result, and there is no study summarizing these findings.
Zohreh Sadat Sangsefidi, Sepideh Soltani, Fatemeh Meshkini, Kimia Torabynasab, Sheida Zeraattalab-Motlagh, Elham Razmpoosh, Mahdi Hejazi, Masoumeh Khalighi Sikaroudi, Shima Abdollahi   +8 more
doaj   +2 more sources