Results 21 to 30 of about 207,610 (292)

Investigation of insulin-like growth factors/insulin-like growth factor binding proteins regulation in metabolic syndrome patients [PDF]

BMC Research Notes, 2019
Objective The insulin-like growth factors (IGFs) and their binding proteins (IGFBPs) are thought to play a significant role in metabolic pathways and glucose metabolism.
Somayeh Pouriamehr, Haleh Barmaki, Mozhdeh Rastegary, Farzaneh Lotfi, Mohsen Nabi Afjadi   +4 more
doaj   +2 more sources

Insulin-like growth factors and insulin-like growth factor binding proteins in mammary gland function [PDF]

Breast Cancer Research, 2002
Insulin-like growth factor (IGF)-mediated proliferation and survival are essential for normal development in the mammary gland during puberty and pregnancy. IGFs interact with IGF-binding proteins and regulate their function. The present review focuses on the role of IGFs and IGF-binding proteins in the mammary gland and describes how modulation of ...
Marshman, Emma, Streuli, Charles H.
openaire   +4 more sources

Pan‐cancer analysis of oncogenic role of insulin‐like growth factor‐binding proteins and validation in ovarian cancer [PDF]

Cancer Medicine, 2023
Background Numerous studies have shown that the insulin‐like growth factor (IGF) pathway is highly associated with tumor initial and progression in several tumors.
Wei Tan, Jie Zhang, Zhimin Deng, Fangfang Dai, Lujia Tang, Wei Hu, Hua Liu   +6 more
doaj   +2 more sources

Association between serum levels of insulin-like growth factor-binding proteins at admission and outcomes at 3 months after acute ischemic stroke [PDF]

Annals of Medicine
Background Insulin-like growth factor-binding proteins (IGFBPs) contribute to central nervous system development and may influence recovery after stroke.
Yuyi Zhu, Huan Wang, Ting Cui, Mingxi Chen, Yaqi Chen, Simiao Wu, Zilong Hao, Shihong Zhang, Xinyi Leng, Deren Wang   +9 more
doaj   +2 more sources

Expression profile, clinical significance, and biological function of insulin-like growth factor 2 messenger RNA-binding proteins in non–small cell lung cancer

Tumor Biology, 2017
Insulin-like growth factor 2 messenger RNA-binding proteins have been described to associate with malignant process in many cancers. However, the role of insulin-like growth factor 2 messenger RNA-binding protein family has not been thoroughly elucidated
Run Shi, Xinnian Yu, Yajing Wang, Jing Sun, Qi Sun, Wenjie Xia, Gaochao Dong, Anpeng Wang, Zhaojia Gao, Feng Jiang, Lin Xu   +10 more
doaj   +2 more sources

Effectiveness of low-fat diet on the levels of insulin-like growth factor-1 and insulin-like growth factor binding proteins: a systematic review and meta-analysis of randomized controlled clinical trials [PDF]

Journal of Health, Population and Nutrition
Background Previous researches on the effect of low-fat diet (LF) on insulin-like growth factor-1 (IGF-1), and its binding proteins (IGFBPs) did not reach a consensus result, and there is no study summarizing these findings.
Zohreh Sadat Sangsefidi, Sepideh Soltani, Fatemeh Meshkini, Kimia Torabynasab, Sheida Zeraattalab-Motlagh, Elham Razmpoosh, Mahdi Hejazi, Masoumeh Khalighi Sikaroudi, Shima Abdollahi   +8 more
doaj   +2 more sources

Fasting Induces Gene Expression of Insulin-like Growth Factor-binding Proteins in Skeletal Muscles of Chicks [PDF]

The Journal of Poultry Science
In mammals, evidence suggests that insulin-like growth factor-binding proteins (IGFBPs) affect skeletal muscle growth in an autocrine and paracrine manner.
Asmaa S. El-far, Haruki Osada, Yumi Sakanashi, Takaoki Saneyasu, Kazuhisa Honda   +4 more
doaj   +2 more sources

The Role of Insulin-Like Growth Factor Binding Proteins

Neuroendocrinology, 2006
Insulin-like growth factors (IGFs) are fundamental cell regulators with an evolutionary conserved role synchronising tissue growth, development and function according to metabolic conditions. Although structurally very similar to insulin, the IGFs act in a very different way as cell regulators. Whereas insulin is stored in a specific gland and released
Perks, Claire, Holly, Jeffrey M P
openaire   +4 more sources

Insulin-Like Growth Factor Binding Proteins and IGFBP Proteases: A Dynamic System Regulating the Ovarian Folliculogenesis [PDF]

Frontiers in Endocrinology, 2018
The aim of the present article is to update our understanding of the expression of the insulin-like growth factor binding proteins (IGFBPs), IGFBP proteases and their implication in the different processes of ovarian folliculogenesis in mammals.
Sabine Mazerbourg, Philippe Monget
doaj   +2 more sources

Transferrin binds insulin‐like growth factors and affects binding properties of insulin‐like growth factor binding protein‐3 [PDF]

FEBS Letters, 2001
In the circulation, most of the insulin‐like growth factors (IGFs) are bound to a ternary 150 kDa complex with IGF‐binding protein (IGFBP)‐3 and the acid labile subunit. In the current study, we identify transferrin (Tf) by mass spectrometry, and immunoprecipitation as a component of a major IGF‐binding fraction separated from human plasma.
Storch, S., Kubler, B., Honing, S., Ackmann, M., Zapf, J., Blum, W., Braulke, Thomas   +6 more
openaire   +3 more sources