Results 221 to 230 of about 590,806 (400)

Engineering a Synthetic Extra-Cellular Matrix for In Vitro Cartilage Tissue Production

open access: yes, 2007
In this study, growth factor binding found in natural extra-cellular matrix (ECM) was mimicked by a modified polymer scaffold that could attract either Insulin-Like Growth Factor-I (IGF-I), a growth factor known to stimulate ECM production by ...
Owens, Gwen
core  

Emerging Therapeutic Strategies for Hearing Loss

open access: yesAdvanced Therapeutics, EarlyView.
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han   +9 more
wiley   +1 more source

Essential Amino Acid Intake Is Required for Sustaining Serum Insulin-like Growth Factor-I Levels but Is Not Necessarily Needed for Body Growth. [PDF]

open access: yesCells, 2022
Nishi H   +11 more
europepmc   +1 more source

AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells

open access: yesAdvanced Science, EarlyView.
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu   +8 more
wiley   +1 more source

Upregulation of Insulin-like Growth Factor-I in Response to Chemotherapy in Children with Acute Lymphoblastic Leukemia. [PDF]

open access: yesInt J Mol Sci
Kocadag HB   +9 more
europepmc   +1 more source

Reduced Insulin-Like Growth Factor-I Effects in the Basal Forebrain of Aging Mouse. [PDF]

open access: yesFront Aging Neurosci, 2021
Zegarra-Valdivia JA   +6 more
europepmc   +1 more source

Insulin-like growth factor I in cultured rat astrocytes: expression of the gene, and receptor tyrosine kinase.

open access: bronze, 1987
Robert Ballotti   +6 more
openalex   +1 more source

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