Engineering a Synthetic Extra-Cellular Matrix for In Vitro Cartilage Tissue Production
In this study, growth factor binding found in natural extra-cellular matrix (ECM) was mimicked by a modified polymer scaffold that could attract either Insulin-Like Growth Factor-I (IGF-I), a growth factor known to stimulate ECM production by ...
Owens, Gwen
core
Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
Heritability and Correlation Estimates for Serum Insulin-like Growth Factor I Concentration, Weight, Weight Gain, and Height in Angus Beef Cattle in a Long-Term Divergent Selection Study for Serum Insulin-like Growth Factor I (1989 to 2017). [PDF]
Davis ME, Simmen RCM.
europepmc +1 more source
Essential Amino Acid Intake Is Required for Sustaining Serum Insulin-like Growth Factor-I Levels but Is Not Necessarily Needed for Body Growth. [PDF]
Nishi H+11 more
europepmc +1 more source
97 HUMAN FETAL AND ADULT CHONDROCYTES: CLONAL GROWTH PROMOTION BY INSULIN LIKE GROWTH FACTORS I AND II, INSULIN AND GROWTH HORMONE [PDF]
U. Vetter+6 more
openalex +1 more source
AAVR Expression is Essential for AAV Vector Transduction in Sensory Hair Cells
Decreased sensitivity to AAV vector transduction in the outer hair cells (OHCs) of adult mice is primarily attributed to reduction of AAVR (Kiaa0319l; Au040320). Knockout of AAVR reduces AAV vector transduction efficiency in both inner hair cells (IHCs) and OHCs in neonatal mice.
Fan Wu+8 more
wiley +1 more source
Upregulation of Insulin-like Growth Factor-I in Response to Chemotherapy in Children with Acute Lymphoblastic Leukemia. [PDF]
Kocadag HB+9 more
europepmc +1 more source
Reduced Insulin-Like Growth Factor-I Effects in the Basal Forebrain of Aging Mouse. [PDF]
Zegarra-Valdivia JA+6 more
europepmc +1 more source