Results 21 to 30 of about 530,055 (311)

Genomewide meta-analysis identifies loci associated with IGF-I and IGFBP-3 levels with impact on age-related traits [PDF]

open access: yes, 2016
The growth hormone/insulin-like growth factor (IGF) axis can be manipulated in animal models to promote longevity, and IGF-related proteins including IGF-I and IGF-binding protein-3 (IGFBP-3) have also been implicated in risk of human diseases including ...
Aschard, H. (Hugues)   +85 more
core   +1 more source

Customized biomaterials to augment chondrocyte gene therapy [PDF]

open access: yes, 2017
A persistent challenge in enhancing gene therapy is the transient availability of the target gene product. This is particularly true in tissue engineering applications.
Aguilar, Izath Nizeet   +3 more
core   +1 more source

Niveles séricos de los factores de crecimiento similares a la insulina I y II y su proteína 3 de enlace en mujeres con lesiones escamosas intraepiteliales y cáncer de cuello uterino

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2006
Introducción. La citología cervico-uterina como prueba de tamizaje del cáncer cervical tiene limitaciones. Un marcador que permita identificar mujeres en riesgo de desarrollar este cáncer sería de utilidad para prevenir el desarrollo de esta enfermedad ...
Martha Lucía Serrano   +4 more
doaj   +1 more source

Insulin-like growth factor-I and its binding proteins in healthy mothers and their newborns [PDF]

open access: yesEinstein (São Paulo), 2004
Objective: To determine serum levels of insulin-like growth factor-I, free insulin-like growth factor-I and its binding proteins in maternalserum and in cord blood of two groups of newborns with differentbirth weights.
Rosanna Velleca Lima   +3 more
doaj  

Pengaruh Pemberian Hormon Igf-I (Insulin-Like Growth Factor-I) Recombinant Mouse terhadap Pertumbuhan Ikan Gurame (Osphronemus Gouramy)
[ Effect of hormones Recombinant Mouse IGF-I (Insulin-Like Growthfactor-I) on The Growth of Osphronemus gouramy]

open access: yesJurnal Ilmiah Perikanan dan Kelautan, 2016
Abstrak Konsumsi ikan gurame semakin meningkat setiap tahun mengakibatkan tingginya jumlah permintaan, belum dapat diimbangi produksi yang mencukupi. Laju pertumbuhan ikan gurame dikenal lambat, sehingga untuk mencapai ukuran konsumsi diperlukan waktu ...
Woro Hastuti Satyantini   +2 more
doaj   +1 more source

Revisiting the IGF-1R as a breast cancer target

open access: yesnpj Precision Oncology, 2017
The type I insulin-like growth factor-1 receptor is a well-described target in breast cancer and multiple clinical trials examining insulin-like growth factor-1 receptor have been completed.
Roudy Chiminch Ekyalongo, Douglas Yee
doaj   +1 more source

Human conditions of insulin-like growth factor-I (IGF-I) deficiency

open access: yesJournal of Translational Medicine, 2012
Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in response to the endocrine GH stimulus, but it is also secreted by multiple tissues for autocrine/paracrine purposes. IGF-I is partly responsible for systemic GH
Puche Juan E, Castilla-Cortázar Inma
doaj   +1 more source

Ovarian Insulin-Like Growth Factor-I

open access: yesAgricultural Science Digest - A Research Journal, 2020
The insulin-like growth factor-I is a pleotropic growth factor that modulates cell replication. Insulin-like growth factor-I is produced by granulosa, theca and luteal cells and have autocrine and paracrine actions. It plays a crucial role in animal fertility acting as a monitoring signal.
M. Bijna, K. Karthiayini
openaire   +1 more source

Growth Hormone Receptor Gene Expression Increase Reflects Nutritional Status Improvement in Patients Affected by Crohn's Disease

open access: yesFrontiers in Pediatrics, 2018
Background: We proposed to verify the role of growth hormone receptor gene expression in growth failure of children with Crohn's disease (CD).Methods: We measured serum levels of growth hormone binding protein (GHBP) and insulin-like growth factor-I (IGF-
Sara Pagani   +7 more
doaj   +1 more source

The insulin-like growth factor I receptor regulates glucose transport by astrocytes [PDF]

open access: yes, 2016
Previous findings indicate that reducing brain insulin-like growth factor I receptor (IGF-IR) activity promotes ample neuroprotection. We now examined a possible action of IGF-IR on brain glucose transport to explain its wide protective activity, as ...
Allaman   +49 more
core   +1 more source

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