Results 51 to 60 of about 530,055 (311)

Obesity is positively associated with dehydroepiandrosterone sulfate concentrations at 7 y in Chilean children of normal birth weight. [PDF]

, 2013
BACKGROUND: In low-birth-weight girls, obesity increases the risk of premature adrenarche and metabolic complications. However, the consistency of this association in normal-birth-weight children and its potential mediators remain unknown.
Baquedano, Camila Corvalán, Charkaluk, Cohen, Cook, Corvalán, de Onis, D’Adamo, Fernandez, Genazzani, Gonzales, Guercio, Guercio, Havelock, Ibáñez, Ibáñez, Ibáñez, Idkowiak, Iñiguez, Jean, Kain, Kelnar, Khan, l’Allemand, Mentzel, Mericq, Ong, Palmert, Parker, Popkin, Rainey, Remer, Remer, Ricardo Uauy, Rittmaster, Rosenfield, Silfen, Slaughter, Smith, Sopher, Tanner, Topor, Utriainen, Verónica Mericq, Williams, Yu   +45 more
core   +1 more source

Bioactive Insulin-Like Growth Factor-I in Obesity [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2009
In obesity, total IGF-I is not reduced to the degree predicted by low GH levels, and free IGF-I levels are normal to high. Total and free IGF-I may not reflect IGF-I biological activity because immunoassays cannot account for the modifying effects of IGF binding proteins on interactions between IGF-I and its receptor.The aim of the study was to ...
J, Frystyk, D J, Brick, A V, Gerweck, A L, Utz, K K, Miller   +4 more
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Insulin-like growth factor (IgF)-I, IgF binding protein-3, and prostate cancer: correlation with gleason score

International Brazilian Journal of Urology, 2015
Introduction Non-androgenic growth factors are involved in the growth regulation of prostate cancer (PCa). Objective This is the first Brazilian study to correlate, in a population of patients operated for PCa, PSA, total testosterone, insulin-like ...
Lívia L. Corrêa, Leonardo Vieira Neto, Giovanna A. Balarini Lima, Rafael Gabrich, Luiz Carlos D. de Miranda, Mônica R. Gadelha   +5 more
doaj   +1 more source

Multiple Myeloma in a Patient with Acromegaly [PDF]

Endocrinology and Metabolism, 2015
Acromegaly is a slowly progressing condition resulting from excess growth hormone (GH), generally caused by a GH-secreting pituitary adenoma. Cancer is the third most common cause of mortality in patients with acromegaly, and insulin-like growth factor 1
Yu Mi Kang, Jong Han Choi, Min Jung Lee, Ari Ahn, Chan-Jeoung Park, Kiju Chang, Seyoung Seo, Sun In Hong, Min-Seon Kim   +8 more
doaj   +1 more source

The glial growth factors deficiency and synaptic destabilization hypothesis of schizophrenia [PDF]

, 2002
Background A systems approach to understanding the etiology of schizophrenia requires a theory which is able to integrate genetic as well as neurodevelopmental factors.
A Sawa, II Gottesman, HW Moises, II Gottesman, RM Murray, S Marenco, HWM Moises, DA Lewis, CS Monk, SJ Webb, G Lemke, DR Cotter, Y Hakak, M Rothermundt, DR Lara, NM Williams, AB Goodman, ABr Niculescu, K Mirnics, S Burden, A Buonanno, H Song, PG Haydon, A Araque, SJ Morley, O Steward, EM Schuman, L Fromm, P Bezzi, YZ Huang, ES Anton, V Calaora, D Wolpowitz, JA Loeb, K Adlkofer, JY Wang, MA Olayioye, Y Liu, MK Sapru, DE Syroid, CM Hertig, C Sweeney, LA Scheving, R Li, MP Allen, S Goruppi, R Eilam, GS Naeve, P Subramony, JS Cameron, H Thoenen, M Canossa, U Otten, M Canossa, E Alleva, RR Baliga, M Kleijn, DG Wells, ER Kandel, M Shelly, R Gerlai, JC Conover, JP Wagner, AL Boxer, DM Araujo, EC Beattie, R Hemi, A Carrie, JH Pak, H Häfner, J Klosterkötter, WIB Beveridge, S Leonard, R Freedman, J Williams, N Iwata, E Jonsson, RS Devon, J Wei, HW Moises, V Dror, H Liu, A Chakravarti, KV Chowdari, S Wang, R Meller, SG Thompson, KM Druey, C Rio, A Araque, R Freedman, K O'Donnell, JR Florini, VK Han, YS Nakamura, A Dupont, M Saku, EF Torrey, N Giannoukakis, H Sasaki, L Magnaghi-Jaulin, W Lin, JW Crayton, J-Stanton Ross, DH Mathalon, H Thoenen, C Frith, VL Nimgaonkar, M Avila, S Jones, LF Kastrukoff, B Schweighardt, AV Albright, JE Friedman, PB Challoner, DA Clark, S Bofill-Mas, EO Major, J Gordon, A Tretiakova, S Bofill-Mas, KM Weiss, JR Kidd, D Wang, AD Long, LB Jorde, DF Levinson, JA Badner, J Altmüller, NJ Risch, M Wudarsky, RG Petty, H Wetzel, G Grunder, CJ Bench, K Otani, KM Yazici, KI Melkersson, KI Melkersson, A Petronis, EF Torrey, JS Kim, JW Olney, SE Antonarakis, V Arolt, U Bailer, CL Barr, JL Blouin, LM Brzustowicz, Q Cao, J Collinge, H Coon, H Coon, TJ Crow, J Dann, LE DeLisi, LE DeLisi, J Ekelund, SV Faraone, DL Garver, M Gill, HM Gurling, I Hovatta, CA Kaufmann, KS Kendler, VK Lasseter, DF Levinson, DF Levinson, MW Lin, MW Lin, E Lindholm, M Maziade, M Maziade, HW Moises, S Nanko, T Paunio, AE Pulver, AE Pulver, AE Pulver, MI Rees, BP Riley, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SG Schwab, SH Shaw, R Sherrington, JM Silverman, D St Clair, G Stöber, RE Straub, RE Straub, RE Straub, WJ Turner, HP Vallada, S Wang, DB Wildenauer, NM Williams, E Lander, V Chalifa-Caspi, II Gottesman, JM Tanner, HT Chugani, MR Cohen   +205 more
core   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Pregnancy rates and metabolic profiles in cattle treated with propylene glycol prior to embryo transfer [PDF]

, 2011
The objective of this study was to determine the effect of a sustained propylene glycol administration to recipients of frozen/thawed in vivo derived bovine embryos.
Duque, Paloma, Díez, Carmen, Facal, Nieves, Fernández, Itziar, Fernández, Lina, Goyache, Félix, Gómez, Enrique, Olegario, Carlos, Prieto, Lupicinio   +8 more
core  

Drugs of abuse and the adolescent athlete [PDF]

, 2010
Doping with endocrine drugs is quite prevalent in amateur and professional athletes. The World Anti-Doping Agency (WADA) has a list of banned drugs for athletes who compete and a strategy to detect such drugs.
Alan D Rogol
core   +1 more source