Immunohistochemical analysis of insulin‐like growth factor I, insulin‐like growth factor I receptor and insulin‐like growth factor II in endometriotic tissue and endometrium [PDF]
Acta Obstetricia et Gynecologica Scandinavica, 1997 Background. The purpose of this study was to investigate unprecedentedly immunohistochemical localization of insulin‐like growth factor I, insulin‐like growth factor I receptor and insulin‐like growth factor II in endometriotic tissue, and to compare ...
Shiuh Y. Chang, Yat‐Sen Ho
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Insulin-like growth factor-II: new roles for an old actor [PDF]
Frontiers in Endocrinology, 2012 IGF-II, traditionally considered as a growth factor implicated in growth of fetal tissues and cancer cells, is now emerging as a potential metabolic regulator.
Stefano eCianfarani
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Surgical resection of a retroperitoneal liposarcoma producing insulin-like growth factor II: a case report [PDF]
Surgical Case Reports, 2023 Background Tumor-produced high molecular weight insulin-like growth factor-II (big insulin-like growth factor-II) is considered to cause non-islet cell tumor hypoglycemia. This paper presents a case of surgically resected retroperitoneal liposarcoma that
Noriyuki Nishiwaki +11 more
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Insulin-Like Growth Factor-II and Ischemic Stroke—A Prospective Observational Study [PDF]
Life, 2021 Insulin-like growth factor-II (IGF-II) regulates prenatal brain development, but the role in adult brain function and injury is unclear. Here, we determined whether serum levels of IGF-II (s-IGF-II) are associated with mortality and functional outcome ...
Daniel Åberg +7 more
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Expression of insulin-like growth factor II and receptors for insulin-like growth factor II, insulin-like growth factor I and insulin in isolated and cultured rat hepatocytes [PDF]
Hepatology, 1991 Insulin-like growth factor II is believed to play an important role in fetal growth and development. The insulin-like growth factor II gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor II messenger RNA and protein in human hepatocellular ...
Eugénia Lamas +4 more
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Insulin-like growth factor-II and bioactive proteins containing a part of the E-domain of pro-insulin-like growth factor-II. [PDF]
Biofactors, 2020 AbstractInsulin‐like growth factor (IGF)‐II is considered to function as an important fetal growth factor, which is structurally and functionally related to IGF‐I and proinsulin. At least in vitro, IGF‐II actions are mediated through the IGF‐I receptor and to a lesser extent the insulin receptor.
van Doorn J.
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Insulin-Like Growth Factor II Targets the mTOR Pathway to Reverse Autism-Like Phenotypes in Mice. [PDF]
J Neurosci, 2018 Autism spectrum disorder (ASD) is a developmental disability characterized by impairments in social interaction and repetitive behavior, and is also associated with cognitive deficits.
Steinmetz AB +4 more
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Expression of the insulin-like growth factor II gene in the choroid plexus and the leptomeninges of the adult rat central nervous system. [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 1988 The rat insulin-like growth factor II gene, encoding a fetal somatomedin, expresses a multitranscript family in embryonic/fetal tissues and in the adult brain and spinal cord.
Fotini Stylianopoulou +3 more
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Insulin-like growth factor II prevents oxidative and neuronal damage in cellular and mice models of Parkinson's disease [PDF]
Redox Biology, 2021 Oxidative distress and mitochondrial dysfunction, are key factors involved in the pathophysiology of Parkinson's disease (PD). The pleiotropic hormone insulin-like growth factor II (IGF-II) has shown neuroprotective and antioxidant effects in some ...
Elisa Martín-Montañez +13 more
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Association of insulin-like growth factor II mrna-binding protein 3 (IMP3) expression with prognostic and morphological factors in endometrial cancer [PDF]
Revista Brasileira de Ginecologia e ObstetríciaObjective Endometrial cancer (EC) is a heterogeneous disease with recurrence rates ranging from 15 to 20%. The discrimination of cases with a worse prognosis aims, in part, to reduce the length of surgical staging in cases with a better prognosis.
Silas Otero Reis Salum +5 more
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