Results 21 to 30 of about 411,574 (298)

Relationship between Metal Pollution and Gene Expression of Insulin-like Growth Factor II [PDF]

Journal of Health and Pollution, 2018
Background. Metals pollution plays an important role in the regulation of gene expression through interference with signal transduction pathways which are important for cell bioactivity. Objectives.
Aziza A. Saad, Amany El-Sikaily, Maher A. Kamel, Hany Kassem, Mohamed S. Abdel-Latif   +4 more
doaj   +2 more sources

Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine [PDF]

Stem Cell Reports, 2019
Summary: Tissue-specific stem cells have unique properties and growth requirements, but a small set of juxtacrine and paracrine signals have been identified that are required across multiple niches.
Amber N. Ziegler, Qiang Feng, Shravanthi Chidambaram, Jaimie M. Testai, Ekta Kumari, Deborah E. Rothbard, Miguel Constancia, Ionel Sandovici, Tara Cominski, Kevin Pang, Nan Gao, Teresa L. Wood, Steven W. Levison   +12 more
doaj   +2 more sources

How IGF-II Binds to the Human Type 1 Insulin-like Growth Factor Receptor [PDF]

Structure, 2020
Human type 1 insulin-like growth factor receptor (IGF-1R) signals chiefly in response to the binding of insulin-like growth factor I. Relatively little is known about the role of insulin-like growth factor II signaling via IGF-1R, despite the affinity of
Nicholas S Kirk, Tristan I Croll, Jarrod J Sandow   +2 more
exaly   +4 more sources

Insulin-like growth factors: Ligands, binding proteins, and receptors

Molecular Metabolism, 2021
Background: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in normal human physiology and disease states.
Derek LeRoith, Jeff M.P. Holly, Briony E. Forbes   +2 more
doaj   +3 more sources

Insulin-like growth factor binding protein-1 at the maternal-fetal interface and insulin-like growth factor-I, insulin-like growth factor-II, and insulin-like growth factor binding protein-1 in the circulation of women with severe preeclampsia

American Journal of Obstetrics and Gynecology, 1997
Preeclampsia is characterized by maternal hypertension, proteinuria, edema, and shallow placental invasion. Insulin-like growth factor binding protein-1, abundant in maternal decidua, is believed to play a role in limiting trophoblast invasiveness.
L C, Giudice, N A, Martina, R A, Crystal, S, Tazuke, M, Druzin   +4 more
exaly   +3 more sources

Insulin-Like Growth Factors, Binding Proteins and Their Role in Pregnancy in Patients With Diabetes [PDF]

Journal of Diabetes Research
The insulin-like growth factor (IGF) axis, an evolutionarily conserved system, is critical in regulating cell growth, proliferation, and survival, affecting nearly all organ systems.
Aleksandra Gladych-Macioszek, Katarzyna Ozegowska, Sandra Radzicka-Mularczyk, Rafał Sibiak, Gernot Desoye, Ewa Wender-Ozegowska   +5 more
doaj   +2 more sources

Expression of insulin-like growth factor II and receptors for insulin-like growth factor II, insulin-like growth factor I and insulin in isolated and cultured rat hepatocytes [PDF]

Hepatology, 1991
Insulin-like growth factor II is believed to play an important role in fetal growth and development. The insulin-like growth factor II gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor II messenger RNA and protein in human hepatocellular ...
E, Lamas, F, Zindy, D, Seurin, C, Guguen-Guillouzo, C, Brechot   +4 more
openaire   +3 more sources

A case of nonislet cell tumor hypoglycemia associated with malignant mesothelioma requiring a multifaceted approach for optimal glycemic control

Clinical Case Reports, 2021
Nonislet tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by refractory hypoglycemia, which often requires multifaceted therapy.
Mariko Ono, Yuki Maeda, Nobuyuki Koyama, Terumasa Nagase, Yoshiya Katsura, Hiroyuki Nakamura, Kazutetsu Aoshiba   +6 more
doaj   +1 more source

Malignant fibroma presenting as a hypoglycemia and coma in a 45‐year‐old male patient: A case report

Clinical Case Reports, 2022
Solitary fibrous tumors (SFTs) are a rare group of spindle cell neoplasm of submesothelial origin with malignant potential and can present as hypoglycemia secondary to excess secretion of insulin‐like growth factor II (IGF‐II) from the tumor.
Muhammad Hanif, Vikash Jaiswal, Sidra Naz, Nirmit Patel, Nishan Babu Pokhrel, Mounika Reddy Vadiyala   +5 more
doaj   +1 more source

Associations Between IGF-II Gene Polymorphism and Milk Yield Characteristics In Brown Swiss Cattle

Turkish Journal of Agriculture: Food Science and Technology, 2023
This study was carried out on 114 Brown Swiss cattle reared in intensive conditions at Ataturk University Food and Livestock Application and Research Center and at the private cattle farm found in Erzurum province.
Esma Yuca, Sinan Kopuzlu
doaj   +1 more source