Insulin-like Growth Factor II: An Essential Adult Stem Cell Niche Constituent in Brain and Intestine [PDF]
Stem Cell Reports, 2019 Summary: Tissue-specific stem cells have unique properties and growth requirements, but a small set of juxtacrine and paracrine signals have been identified that are required across multiple niches.
Amber N. Ziegler +12 more
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Insulin-like growth factors: Ligands, binding proteins, and receptors
Molecular Metabolism, 2021 Background: The insulin-like growth factor family of ligands (IGF-I, IGF-II, and insulin), receptors (IGF-IR, M6P/IGF-IIR, and insulin receptor [IR]), and IGF-binding proteins (IGFBP-1-6) play critical roles in normal human physiology and disease states.
Derek LeRoith +2 more
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American Journal of Obstetrics and Gynecology, 1997 Preeclampsia is characterized by maternal hypertension, proteinuria, edema, and shallow placental invasion. Insulin-like growth factor binding protein-1, abundant in maternal decidua, is believed to play a role in limiting trophoblast invasiveness.
Maurice Druzin
exaly +3 more sources
Expression of insulin-like growth factor II and receptors for insulin-like growth factor II, insulin-like growth factor I and insulin in isolated and cultured rat hepatocytes [PDF]
Hepatology, 1991 Insulin-like growth factor II is believed to play an important role in fetal growth and development. The insulin-like growth factor II gene expression is tissue specific and developmentally regulated. We have previously shown an enhanced level of insulin-like growth factor II messenger RNA and protein in human hepatocellular ...
E, Lamas +4 more
openaire +3 more sources
Clinical Case Reports, 2021 Nonislet tumor hypoglycemia (NICTH) is a rare paraneoplastic syndrome characterized by refractory hypoglycemia, which often requires multifaceted therapy.
Mariko Ono +6 more
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Malignant fibroma presenting as a hypoglycemia and coma in a 45‐year‐old male patient: A case report
Clinical Case Reports, 2022 Solitary fibrous tumors (SFTs) are a rare group of spindle cell neoplasm of submesothelial origin with malignant potential and can present as hypoglycemia secondary to excess secretion of insulin‐like growth factor II (IGF‐II) from the tumor.
Muhammad Hanif +5 more
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Associations Between IGF-II Gene Polymorphism and Milk Yield Characteristics In Brown Swiss Cattle
Turkish Journal of Agriculture: Food Science and Technology, 2023 This study was carried out on 114 Brown Swiss cattle reared in intensive conditions at Ataturk University Food and Livestock Application and Research Center and at the private cattle farm found in Erzurum province.
Esma Yuca, Sinan Kopuzlu
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Understanding the mechanism of insulin and insulin-like growth factor (IGF) receptor activation by IGF-II. [PDF]
PLoS ONE, 2011 BACKGROUND: Insulin-like growth factor-II (IGF-II) promotes cell proliferation and survival and plays an important role in normal fetal development and placental function.
Clair L Alvino +6 more
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Determinants of IGF-II influencing stability, receptor binding and activation
Scientific Reports, 2022 Insulin like growth factor II (IGF-II) is involved in metabolic and mitogenic signalling in mammalian cells and plays important roles in normal fetal development and postnatal growth.
Andrew Blyth +4 more
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Recurrent Severe Hypoglycemia Secondary to Benign Phyllodes Tumour of the Breast
Journal of the ASEAN Federation of Endocrine Societies, 2022 Non-Islet Cell Tumor-induced hypoglycemia (NICTH) secondary to phyllodes tumour is extremely rare but potentially life threatening if not treated promptly.
Hwee Ching Tee, Vijiya Mala Valayatham
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