Results 111 to 120 of about 418,496 (299)

Molecular evolution of growth hormone [PDF]

, 2014
Growth hormone (GH) is a single-chain protein hormone of about 190 residues, expressed mainly in the vertebrate anterior pituitary gland, which regulates somatic growth and various aspects of metabolism; many of these actions are mediated by insulin ...
Wallis, Michael
core  

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source

Insulin-like Growth Factor II mRNA-Binding Protein 1 Regulates Pancreatic Cancer Cell Growth through the Surveillance of CDC25A mRNA. [PDF]

Cancers (Basel), 2023
Di Fusco D, Segreto MT, Di Maggio G, Iannucci A, Maresca C, Di Grazia A, Colella M, Stolfi C, Monteleone G, Monteleone I.   +9 more
europepmc   +1 more source

4D Mapping of ZIF Biocomposites for High Protein Loading and Tunable Release Profiles

Advanced Functional Materials, EarlyView.
Systematic four‐dimensional mapping of zeolitic imidazolate framework biocomposites reveals how precursor ratios, total concentration, and washing define crystalline phase, protein loading, and release kinetics. This comprehensive study identifies conditions yielding record loading (∼85%) and precise phase–property correlations.
Michael R. Hafner, Francesco Carraro, Behnaz Abbasgholi‐NA, Simone Dal Zilio, Max Schmallegger, Helmar Wiltsche, Lingcong Ge, Michael R. Reithofer, Efwita Astria, Laura Villanova, Heinz Amenitsch, Christian Doonan, Paolo Falcaro   +12 more
wiley   +1 more source

Transactivation of the Insulin-Like Growth Factor-I Receptor by Angiotensin II Mediates Downstream Signaling from the Angiotensin II Type 1 Receptor to Phosphatidylinositol 3-Kinase [PDF]

, 2004
Peter Zahradka, Brenda Litchie, Ben Storie, Gail Helwer   +3 more
openalex   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Insulin-Like Growth Factor-1 and Insulin-Like Growth Factor Binding Protein-3 – Biomarkers for Skeletal Maturity Assessment in Class II Malocclusion

Pesquisa Brasileira em Odontopediatria e Clínica Integrada
Objective: To estimate the serum levels of non-radiologic biomarkers, Insulin-like Growth Factor-1 (IGF-1), and Insulin-like Growth Factor Binding Protein-3 (IGFBP-3) to potentially identify the pubertal growth spurt in skeletal Class II malocclusion ...
Arif Yezdani, Kesavaram Padmavathy, Kishore Kumar   +2 more
doaj  

An insulin-sensitive Drosophila insulin-like receptor mutant remodels methionine metabolism to extend lifespan.

PLoS Genetics
Insulin/insulin growth factor signaling is a conserved pathway that regulates lifespan across many species. Multiple mechanisms are proposed for how this altered signaling slows aging.
Marc Tatar, Wenjing Zheng, Shweta Yadav, Rochele Yamamoto, Noelle Curtis-Joseph, Shengxi Li, Lin Wang, Andrey A Parkhitko   +7 more
doaj   +1 more source

The Expression of Insulin-Like Growth Factor II Messenger RNA-Binding Protein 3 Upregulated in Intradural Extramedullary Schwannomas. [PDF]

Spine Surg Relat Res, 2023
Bekki H, Matsumoto Y, Yoshimoto M, Ishihara S, Kawaguchi K, Yamamoto H, Oda Y, Nakashima Y, Harimaya K.   +8 more
europepmc   +1 more source

Local Insulin-Like Growth Factor-II Mediates Prolactin-Induced Mammary Gland Development [PDF]

, 2003
Russell C. Hovey, Jessica Harris, Darryl L. Hadsell, Adrian V. Lee, Christopher J. Ormandy, Barbara K. Vonderhaar   +5 more
openalex   +1 more source