Results 121 to 130 of about 463,657 (378)

Coordinate expression of insulin-like growth factor II and its receptor during muscle differentiation.

Proceedings of the National Academy of Sciences of the United States of America, 1989
The role of polypeptide growth factors in promoting muscle differentiation is uncharacterized. We have used a fusing skeletal muscle cell line, C2, to examine the endogenous expression of one peptide, insulin-like growth factor II (IGF-II), and its ...
E. Tollefsen, Jenny Levis SADOWt, Peter ROTWEINtt   +2 more
semanticscholar   +1 more source

Co‐overexpression of the caloric restriction‐induced mitochondrial factors PGC‐1α and MIPEP upregulates Phospho1 expression in adipocytes

FEBS Open Bio, EarlyView.
Caloric restriction that extends lifespan induces the expression of PGC‐1α and MIPEP in white adipose tissue. In this study, co‐overexpression of Pgc‐1α and Mipep upregulated the gene expression of PHOSPHO1. These findings provide new insights into mitochondria‐related mechanisms underlying the effects of caloric restriction in adipocytes.
Mamiko Ishimatsu, Kanari Taki, Asuka Hayami, Komachi Kato, Yuka Nozaki, Yuhei Mizunoe, Takumi Narita, Ryoichi Mori, Yoshikazu Higami, Masaki Kobayashi   +9 more
wiley   +1 more source

Specific effects of estrogen on growth factor and major histocompatibility complex class II antigen expression in rat aortic allograft [PDF]

, 1997
Objective: Transplant arteriosclerosis is the major determinant for long-term survival of cardiac transplants. Estradiol treatment inhibits transplant arteriosclerosis. The objective of this study is to determine, in the absence of immunosuppression, the
Arnqvist, Aziz, Cercek, Clark, Delafontaine, Foegh, Fox, Grant, Hong Lou, Howell, Kofnek, Lou, Lou, Marie L. Foegh, More, Motomura, Motomura, Noboru Motomura, Peter W. Ramwell, Reape, Ross, Satoshi Saito, Segnitz, Steimle, Stiles   +24 more
core   +1 more source

The Relationship between Nonalcoholic Fatty Liver Disease and Colorectal Cancer: The Future Challenges and Outcomes of the Metabolic Syndrome

Journal of Obesity, 2012
Nonalcoholic fatty liver disease (NAFLD) is closely related to insulin resistance, metabolic syndrome, obesity, type 2 diabetes, and dyslipidaemia.
Said O. Muhidin, Ahmed A. Magan, Khalid A. Osman, Shareef Syed, Mohamed H. Ahmed   +4 more
doaj   +1 more source

Loss of imprinting of the insulin-like growth factor II gene occurs by biallelic methylation in a core region of H19-associated CTCF-binding sites in colorectal cancer.

Proceedings of the National Academy of Sciences of the United States of America, 2001
We hypothesize that loss of imprinting (LOI) of the insulin-like growth factor II (IGF2) gene is associated with a predisposition to sporadic colorectal cancer. We confirmed a previously known strong correlation between LOI and microsatellite instability
H. Nakagawa, R. Chadwick, P. Peltomäki, C. Plass, Y. Nakamura, A. Chapelle   +5 more
semanticscholar   +1 more source

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

Metabolic Consequences of Rheumatoid Arthritis

Arthritis Care &Research, EarlyView.
Patients with rheumatoid arthritis (RA) may have metabolic disruption, which can contribute to adverse long‐term outcomes, for multiple reasons. Patients with RA appear to have a higher risk of sarcopenia, type 1 and type 2 diabetes mellitus, metabolic syndrome, and hypertension. Systemic inflammation in RA can cause a “lipid paradox,” with reduced low‐
Stevie Barry, Emily Sheng, Joshua F. Baker   +2 more
wiley   +1 more source

Double jeopardy: hypoglycaemia and advanced hepatocellular carcinoma [PDF]

, 2013
Nonislet cell tumour-induced hypoglycaemia is an uncommon, but serious complication of malignancy. The aetiopathogenesis is largely as a result of tumoral overproduction of incompletely processed insulin-like growth factor-II.
Huddle, KRI, Nicolaou, V, Shires, R
core   +1 more source

Cryptic receptors for insulin-like growth factor II in the plasma membrane of rat adipocytes — a possible link to cellular insulin resistance [PDF]

, 1996
To further elucidate the mechanisms for short-term regulation of the receptor for insulin-like growth factor II (IGF-II), we investigated effects of insulin, cAMP and phosphatase inhibitors on cell surface 125I-IGF-II binding in rat adipocytes ...
Eriksson, Jan W., Wickman, Annika, Yu, Zhi-Wen   +2 more
core   +1 more source

Doege–Potter Syndrome, cause of nonislet cell tumor hypoglycemia: the first case report from Nepal

International Medical Case Reports Journal, 2017
Vivek Pant,1 Suman Baral,2 Gita Sayami,3 Prakash Sayami4 1Department of Biochemistry, 2Endocrinology Unit, Department of Medicine, 3Department of Pathology, 4Manmohan Cardiothoracic vascular and transplant Center, Institute of Medicine (IOM), Tribhuvan ...
Pant V, Baral S, Sayami G, Sayami P
doaj