A novel model based on interleukin 6 and insulin-like growth factor II for detection of hepatocellular carcinoma associated with hepatitis C virus. [PDF]
J Genet Eng Biotechnol, 2021 Omran MM +4 more
europepmc +1 more source
Advanced Healthcare Materials, EarlyView.This review highlights recent advances in microfluidic technologies for modeling human aging and age‐related diseases. It explores how organ‐on‐chip platforms improve physiological relevance, enable rejuvenation strategies, facilitate drug screening, detect senescent cells, and identify biomarkers.
Limor Zwi‐Dantsis +5 more
wiley +1 more source
Jurnal Veteriner, 2008 The aim of this research was study of Insulin Like Growth -I Complex to level of malondialdehide (MDA) and percentage of intact membrane plasm. Report of several species suggest that seminal plasma contains factors that may influence sperm viability ...
Suherni Susilowati
doaj
The Mechanism of Insulin-Like Growth Factor II mRNA-Binging Protein 3 Induce Decidualization and Maternal-Fetal Interface Cross Talk by TGF-β1 in Recurrent Spontaneous Abortion. [PDF]
Front Cell Dev Biol, 2022 Zhu RH +14 more
europepmc +1 more source
Dendrimer Conjugates with PD‐L1‐Binding Peptides Enhance In Vivo Antitumor Immune Response
Advanced Healthcare Materials, EarlyView.In this paper, a novel nanoparticle scaffold composed of dendrimers conjugated with peptide‐based immune checkpoint inhibitors, enhancing drug delivery efficacy is introduced. By conjugating PD‐L1‐binding peptides to dendrimers, multivalent binding effects are harnessed, resulting in enhanced binding affinity, prolonged half‐life, and improved ...
DaWon Kim +11 more
wiley +1 more source
Regulation of insulin-like growth factor II receptors by growth hormone and insulin in rat adipocytes. [PDF]
, 1987 Peter Lönnroth +6 more
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Animal‐Free Setup of a 3D Mature Adipocyte‐Macrophage Co‐Culture to Induce Inflammation In Vitro
Advanced Healthcare Materials, EarlyView.A completely animal‐free 3D co‐culture is developed using human fat cells and immune cells. Animal‐based materials are replaced with gellan gum hydrogel and a serum‐free medium. Immune cells are effectively activated, producing specific inflammatory signals.
Sophia Nowakowski +3 more
wiley +1 more source
97 HUMAN FETAL AND ADULT CHONDROCYTES: CLONAL GROWTH PROMOTION BY INSULIN LIKE GROWTH FACTORS I AND II, INSULIN AND GROWTH HORMONE [PDF]
, 1985 U. Vetter +6 more
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Multifunctional Biomedical Devices with Closed‐Loop Systems for Precision Therapy
Advanced Healthcare Materials, EarlyView.This review explores two major types of closed‐loop therapeutic systems: self‐sustained and externally triggered. It highlights recent advances in stimuli‐responsive materials, integrated bioelectronics, and data‐driven control strategies, offering insight into emerging strategies for personalized, responsive drug delivery.
Yixuan Leng, Rujie Sun
wiley +1 more source
Permeation Enhancer‐based Ionogel Shows Remarkable Potential for Oral Insulin Delivery
Advanced Healthcare Materials, EarlyView.This study proposes a novel formulation of decanoate in an ionic liquid inspired drug delivery system. The formulation demonstrates ideal physicochemical and material properties for oral peptide delivery. Findings indicate that choline decanoate (1:2 molar ratio) forms a viscoelastic gel that enables high oral bioavailability of insulin in rats ...
Konstantinos Raptis +6 more
wiley +1 more source