Results 111 to 120 of about 14,458,916 (288)

Insulin-like growth factor receptor / mTOR signaling elevates global translation to accelerate zebrafish fin regenerative outgrowth. [PDF]

Dev Biol, 2023
Lewis VM, Le Bleu HK, Henner AL, Markovic H, Robbins AE, Stewart S, Stankunas K.   +6 more
europepmc   +1 more source

Microfluidic Engineering of Microgels: A Review of Emerging Technologies, Materials, Fabrication Strategies, and Applications

Advanced Healthcare Materials, EarlyView.
Recent advances in microfluidic technologies for microgel fabrication are critically reviewed, highlighting the capabilities and limitations of major microfluidic platforms and discussing how platform design, material selection, and crosslinking strategies influence microgel architecture and functionality. Current challenges and future opportunities in
Afshin Abrishamkar, Laura Neely, Cynthia Pham, Nada Ibrahim, Alexis Larios‐Cervantes, Ben A. Kertesz, Todd Hoare   +6 more
wiley   +1 more source

Membrane-anchored intracellular insulin receptor or insulin-like growth factor-1 receptor elicits ligand-independent downstream signaling

Biochemistry and Biophysics Reports
Neurodegenerative diseases including glaucoma affect insulin signaling, and insulin treatment has been shown to reverse the neurodegenerative loss of dendritic complexity in retinal ganglion cells.
Akiko Sotozono, Kazuhiko Namekata, Xiaoli Guo, Youichi Shinozaki, Chikako Harada, Takahiko Noro, Tadashi Nakano, Takayuki Harada   +7 more
doaj   +1 more source

Identification of BRCA1 As a Potential Biomarker for Insulin-Like Growth Factor-1 Receptor Targeted Therapy in Breast Cancer

Frontiers in Endocrinology, 2017
The insulin-like growth factor-1 receptor (IGF1R) emerged in recent years as a promising therapeutic target in oncology. Identification of potential biomarkers capable of predicting response to IGF1R-targeted therapy is of cardinal importance.
Tali Cohen-Sinai, Tali Cohen-Sinai, Zoya Cohen, Haim Werner, Haim Werner, Raanan Berger   +5 more
doaj   +1 more source

Retraction Note: Identification of the cathelicidin peptide LL-37 as agonist for the type I insulin-like growth factor receptor. [PDF]

Oncogene, 2023
Girnita A, Zheng H, Grönberg A, Girnita L, Ståhle M.   +4 more
europepmc   +1 more source

Supplementary Fig. S1 from Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake

, 2008
Supplementary Fig. S1 from Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose ...
An Song (10874351), Wei-Ching Liang (1593526), Yonglei Shang (14909469), Kenji Kozuka (5684108), Jean-Philippe Stephan (40079), Yan Wu (70890), Suzie J. Scales (14895671), Congfen Li (11890795), Zora Modrusan (37892), Sang Hoon Lee (211083), Siao Ping Tsai (1958665), Sarajane Ross (14881149), Klaus Hoeflich (15040823), Alexander Vanderbilt (15040820), Gail Phillips (2372092), Jennifer Batson (3719461), Mark R. Lackner (14886740), Avi Ashkenazi (30123), Simon Williams (155614), Zhijun Tang (9643426), Jiping Zha (4917034), Jihong Yang (585406), Yifan Mao (11903012), Christine Tan (15040817), Klara Totpal (14899089), Janet Tien (14894523)   +25 more
core   +1 more source

Anti‐Inflammatory and Neuroactive Effects of Polymer‐Coated Iron Oxide Nanoparticles Functionalized With Interleukin 4 for Spinal Cord Injury

Advanced Healthcare Materials, EarlyView.
Polymer‐coated IONPs functionalized with IL‐4 display respective neuroactive and anti‐inflammatory actions on neural progenitor cells and macrophages/microglia in vitro. When examined chronically in a rat experimental model of spinal cord injury, rGO scaffolds carrying these nanosystems adequately integrate into the lesion, significantly reduce ...
Julia Martínez‐Ramírez, Paloma Lozano‐Picazo, María de Lamo‐Atencia, Andrea Ferreras, Esther Benayas‐Martín, Elena Fernández‐López, Marina Sánchez‐Petidier, Verónica Barranco‐Maresca, Víctor Caz, Anne des Rieux, Juliana M. Rosa, María del Puerto Morales, María C. Serrano   +12 more
wiley   +1 more source

The insulin receptor cellular IRES confers resistance to eIF4A inhibition

eLife, 2013
Under conditions of stress, such as limited growth factor signaling, translation is inhibited by the action of 4E-BP and PDCD4. These proteins, through inhibition of eIF4E and eIF4A, respectively, impair cap-dependent translation. Under stress conditions
Calla M Olson, Marissa R Donovan, Michael J Spellberg, Michael T Marr II   +3 more
doaj   +1 more source

The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/insulin-like growth factor receptor signaling. [PDF]

J Biol Chem, 2022
Gayen M, Benoit MR, Fan Q, Hudobenko J, Yan R.   +4 more
europepmc   +1 more source

Supplementary Table S2 from Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake

, 2008
Supplementary Table S2 from Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose ...
An Song (10874351), Wei-Ching Liang (1593526), Yonglei Shang (14909469), Kenji Kozuka (5684108), Jean-Philippe Stephan (40079), Yan Wu (70890), Suzie J. Scales (14895671), Congfen Li (11890795), Zora Modrusan (37892), Sang Hoon Lee (211083), Siao Ping Tsai (1958665), Sarajane Ross (14881149), Klaus Hoeflich (15040823), Alexander Vanderbilt (15040820), Gail Phillips (2372092), Jennifer Batson (3719461), Mark R. Lackner (14886740), Avi Ashkenazi (30123), Simon Williams (155614), Zhijun Tang (9643426), Jiping Zha (4917034), Jihong Yang (585406), Yifan Mao (11903012), Christine Tan (15040817), Klara Totpal (14899089), Janet Tien (14894523)   +25 more
core   +1 more source