Results 41 to 50 of about 22,902,059 (175)
Insulin-like peptides encode sensory information to regulate "C. elegans" development [PDF]
, 2010 The sensory system senses and conveys information about an animal’s complex environment to induce the optimal physiological and behavioral responses that are necessary for survival.
Cornils, Astrid
core +1 more source
Molecular Therapy: Nucleic Acids, 2013 Upon functional loss of insulin producing islet β-cells, some patients with diabetes become dependent on life-long insulin supplementation therapy. Bioengineering surrogate insulin producing cells is an alternative replacement strategy. We have developed
Vikash Reebye +9 more
doaj +1 more source
Theca Cell INSL3 and Steroids Together Orchestrate the Growing Bovine Antral Follicle
Frontiers in Physiology, 2017 Insulin-like peptide 3 (INSL3) and its specific receptor RXFP2 are both expressed by theca interna cells of the growing antral follicle where they form an essential regulatory element in the production of the steroid precursor androstenedione.
Yanzhenzi Dai +4 more
doaj +1 more source
Proteolysis of insulin-like growth factor binding proteins (IGFBPs) by calpain [PDF]
, 2005 Calpains are non-lysosomal, Ca2+-dependent cysteine proteases, which are ubiquitously distributed across cell types and vertebrate species. The rules that govern calpain specificity have not yet been determined.
Mann, Karlheinz +12 more
core +1 more source
Frontiers in Endocrinology, 2019 Cryptorchidism, a frequent genital malformation in male newborn, remains in most cases idiopathic. On the basis of experimental, epidemiological, and clinical data, it has been included in the testicular dysgenesis syndrome and believed to be influenced,
Patrick Fénichel +10 more
doaj +1 more source
Adult Human Biliary Tree Stem Cells Differentiate to β-Pancreatic Islet Cells by Treatment with a Recombinant Human Pdx1 Peptide. [PDF]
PLoS ONE, 2015 Generation of β-pancreatic cells represents a major goal in research. The aim of this study was to explore a protein-based strategy to induce differentiation of human biliary tree stem cells (hBTSCs) towards β-pancreatic cells.
Vincenzo Cardinale +15 more
doaj +1 more source
Directed differentiation of rhesus monkey ES cells into pancreatic cell phenotypes
Reproductive Biology and Endocrinology, 2004 Embryonic stem cells (ES) can self-replicate and differentiate into all cell types including insulin-producing, beta-like cells and could, therefore, be used to treat diabetes mellitus.
Nauert Brian +4 more
doaj +1 more source
Cell Reports, 2017 Insulin and insulin-growth-factor-like signaling (IIS) plays important roles in the regulation of development, growth, metabolic homeostasis, and aging, as well as in brain functions such as learning and memory.
Kento Tanabe +2 more
doaj +1 more source
The Regulatory Role of Apelin on the Appetite and Growth of Common Carp (Cyprinus Carpio L.)
Animals, 2020 Apelin, a kind of active polypeptide, has many biological functions, such as promoting food intake, enhancing immunity, and regulating energy balance. In mammals, studies have indicated that apelin is involved in regulating food intake.
Xiao Yan +7 more
doaj +1 more source
Insulin-like growth factor I (IGF-1) Ec/Mechano Growth factor--a splice variant of IGF-1 within the growth plate. [PDF]
PLoS ONE, 2013 Human insulin-like growth factor 1 Ec (IGF-1Ec), also called mechano growth factor (MGF), is a splice variant of insulin-like growth factor 1 (IGF-1), which has been shown in vitro as well as in vivo to induce growth and hypertrophy in mechanically ...
Werner Schlegel +8 more
doaj +1 more source