Results 101 to 110 of about 94,888 (208)

Proteoglycan profiling of human, rat and mouse insulin-secreting cells. [PDF]

Glycobiology, 2021
Nikpour M, Nilsson J, Persson A, Noborn F, Vorontsov E, Larson G.   +5 more
europepmc   +1 more source

Inhibition of miR-146a-5p and miR-8114 in Insulin-Secreting Cells Contributes to the Protection of Melatonin against Stearic Acid-Induced Cellular Senescence by Targeting Mafa. [PDF]

Endocrinol Metab (Seoul), 2022
Su S, Zhao Q, Dan L, Lin Y, Li X, Zhang Y, Yang C, Dong Y, Li X, Regazzi R, Sun C, Chu X, Lu H.   +12 more
europepmc   +1 more source

Adenosine triphosphate is co-secreted with glucagon-like peptide-1 to modulate intestinal enterocytes and afferent neurons

Nature Communications, 2019
Glucagon-like peptide 1 (GLP-1) is released from intestinal L-cells following nutrient uptake and enhances insulin release as well as promotes satiety. Here, the authors demonstrate that GLP-1 secreting cells release ATP and that this stimulates nodose ...
Van B. Lu, Juraj Rievaj, Elisabeth A. O’Flaherty, Christopher A. Smith, Ramona Pais, Luke A. Pattison, Gwen Tolhurst, Andrew B. Leiter, David C. Bulmer, Fiona M. Gribble, Frank Reimann   +10 more
doaj   +1 more source

Using recombinase-mediated cassette exchange to engineer MIN6 insulin-secreting cells based on a newly identified safe harbor locus. [PDF]

J Diabetes Investig, 2021
Furukawa A, Tanaka A, Yamaguchi S, Kosuda M, Yamana M, Nagasawa A, Kohno G, Ishihara H.   +7 more
europepmc   +1 more source

Hyperglycemia-Induced Dysregulated Fusion Intermediates in Insulin-Secreting Cells Visualized by Super-Resolution Microscopy. [PDF]

Front Cell Dev Biol, 2021
Yang G, Li L, Liu Y, Liang K, Wei L, Chen L.   +5 more
europepmc   +1 more source

β-cell CD36 linked to insulin secretion [PDF]

Nature Reviews Endocrinology, 2020
openaire   +2 more sources

No evidence for oncogenic mutations in guanine nucleotide-binding proteins of human adrenocortical neoplasms [PDF]

, 1933
G-Proteins are membrane-bound heterotrimeric polypeptides that couple receptor signals to second messenger systems such as cAMP. Recently, point mutations at 2 codons of the highly preserved alpha-chain of Gs, the adenyl cyclase-stimulating G-protein ...
Chrousos, G. P., Karl, M., Reincke, Martin, Travis, W.   +3 more
core  

Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status

Signal Transduction and Targeted Therapy
The pancreas, an organ with dual functions, regulates blood glucose levels through the endocrine system by secreting hormones such as insulin and glucagon. It also aids digestion through the exocrine system by secreting digestive enzymes.
Chenglin Hu, Yuan Chen, Xinpeng Yin, Ruiyuan Xu, Chenxue Yin, Chengcheng Wang, Yupei Zhao   +6 more
doaj   +1 more source

Clusterin Protects Lipotoxicity-Induced Apoptosis via Upregulation of Autophagy in Insulin-Secreting Cells. [PDF]

Endocrinol Metab (Seoul), 2020
Hong SW, Lee J, Kim MJ, Moon SJ, Kwon H, Park SE, Rhee EJ, Lee WY.   +7 more
europepmc   +1 more source

Efficient targeting to storage granules of human proinsulins with altered propeptide domain. [PDF]

, 1988
In neuronal and endocrine cells, peptide hormones are selectively segregated into storage granules, while other proteins are exported continuously without storage.
Craik, CS, Moore, HP, Orci, L, Powell, SK   +3 more
core