Results 171 to 180 of about 90,101 (333)

Pregnancy-Associated Plasma Protein-A Is the Insulin-Like Growth Factor Binding Protein-4 Protease Secreted by Human Ovarian Granulosa Cells and Is a Marker of Dominant Follicle Selection and the Corpus Luteum [PDF]

open access: bronze, 2001
Cheryl A. Conover   +7 more
openalex   +1 more source

A Bead‐Based Quantum Dot Immunoassay Integrated with Multi‐Module Microfluidics Enables Real‐Time Multiplexed Detection of Blood Insulin and Glucagon

open access: yesAdvanced Science, EarlyView.
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali   +7 more
wiley   +1 more source

Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status

open access: yesSignal Transduction and Targeted Therapy
The pancreas, an organ with dual functions, regulates blood glucose levels through the endocrine system by secreting hormones such as insulin and glucagon. It also aids digestion through the exocrine system by secreting digestive enzymes.
Chenglin Hu   +6 more
doaj   +1 more source

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells [PDF]

open access: bronze, 2001
Sebastian Barg   +11 more
openalex   +1 more source

The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang   +16 more
wiley   +1 more source

EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells. [PDF]

open access: yesMol Biol Cell, 2020
Topalidou I   +4 more
europepmc   +1 more source

Hypoglycemia Induces Diabetic Macrovascular Endothelial Dysfunction via Endothelial Cell PANoptosis, Macrophage Polarization, and VSMC Fibrosis

open access: yesAdvanced Science, EarlyView.
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo   +10 more
wiley   +1 more source

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