Pregnancy-Associated Plasma Protein-A Is the Insulin-Like Growth Factor Binding Protein-4 Protease Secreted by Human Ovarian Granulosa Cells and Is a Marker of Dominant Follicle Selection and the Corpus Luteum [PDF]
Cheryl A. Conover+7 more
openalex +1 more source
The quantum dot integrated real‐time ELISA or QIRT‐ELISA system integrates a bead‐based quantum dot‐mediated immunoassay (BQI) with a modular microfluidic system to continuously monitor insulin and glucagon in whole blood samples and in a multiplexed setting.
Hesam Abouali+7 more
wiley +1 more source
Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status
The pancreas, an organ with dual functions, regulates blood glucose levels through the endocrine system by secreting hormones such as insulin and glucagon. It also aids digestion through the exocrine system by secreting digestive enzymes.
Chenglin Hu+6 more
doaj +1 more source
Establishment of 2-mercaptoethanol-dependent differentiated insulin- secreting cell lines
Maryam Asfari
openalex +1 more source
Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells [PDF]
Sebastian Barg+11 more
openalex +1 more source
The LDH‐H3K18La‐Nur77 Axis Potentiates Immune Escape in Small Cell Lung Cancer
Lactate from SCLC tumors induces H3K18 lactylation in naïve CD8+ T cells, upregulating Nurr77 and enhancing tonic TCR signaling. This leads to T cell hyporesponsiveness to stimulation, impairing antitumor immunity and reducing immunotherapy efficacy.
Xiaoling Shang+16 more
wiley +1 more source
Interleukin-1β Stimulation of c-Jun NH2-Terminal Kinase Activity in Insulin-Secreting Cells [PDF]
Christopher Major, Bryan A. Wolf
openalex +1 more source
EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells. [PDF]
Topalidou I+4 more
europepmc +1 more source
This study investigates hypoglycemia‐induced diabetic macrovascular endothelial dysfunction. It reveals that hypoglycemia triggers ZBP1‐dependent PANoptosis of endothelial cells, proinflammatory polarization of macrophages, and fibrosis of vascular smooth muscle cells (VSMCs) in diabetic mice.
Deyu Zuo+10 more
wiley +1 more source