Results 181 to 190 of about 115,305 (240)

Role of Inflammatory Cytokines and Endocrine Dysregulation in Pain-Related Cardiovascular and Metabolic Dysfunction: A Narrative Review. [PDF]

Cureus
Azeez OM, Olaniyi H, Oyovwi JO, Oyovwi MI, Okafor CP, Folasole A, Okeoma OI, Olaniyi AO.   +7 more
europepmc   +1 more source

PVT1 lincRNA signals an androgen‐dependent transcriptional activation program of oncogenes in prostate cancer cells

International Journal of Cancer, EarlyView.
What's New? Unraveling the networks that regulate androgen receptor (AR) function is critical to better understanding prostate cancer development and progression. Of particular interest in this regard is the long non‐coding RNA PVT1, which regulates gene expression in cancer and is upregulated in prostate tumors.
Maria Gabriela Berzoti‐Coelho, Fabio Nunes de Mello, Ana Carolina Tahira, Gabriel Nakanishi Fortes, Agatha Fischer‐Carvalho, Pedro Jardim Poli, Murilo Sena Amaral, Sergio Verjovski‐Almeida   +7 more
wiley   +1 more source

Diagnostic performance of urinary adipsin as a screening biomarker for pre‐eclampsia

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluated the diagnostic performance of urinary adipsin as a potential biomarker for pre‐eclampsia screening in a low‐resource setting. Methods A case–control study was conducted involving 150 pregnant women classified into three groups: 50 healthy pregnancies, 50 high‐risk pregnancies without pre‐eclampsia, and 50 ...
Bismark Opoku Mensah, Ernestina Anim, Linda Ahenkorah Fondjo, Bernard Gyan, Peter Paul Mwinsanga Dapare   +4 more
wiley   +1 more source

Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000–2024)

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Intrauterine insemination (IUI) is a widely used first‐line fertility treatment, yet its success rates vary considerably. This review synthesizes evidence from peer‐reviewed studies published between 2000 and 2024, including randomized controlled trials, cohort and case–control studies, as well as systematic and narrative reviews identified ...
Kasuni Akalanka
wiley   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

iMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu, Cenlan Bu, Qinzheng Xu, Xi Cheng, Junrong Zhang, Jinling Chen, Yun‐Zhao Xu   +6 more
wiley   +1 more source

Glucose dysregulation and glycemic phenotyping in chronic migraine. [PDF]

Front Neurol
Nelson CA, Reavely KW, Jennings MR, Burger BJ, Kim AC, Sant DW, Bills KB.   +6 more
europepmc   +1 more source

Nano‐plastics disrupt systemic metabolism by remodeling the bile acid–microbiota axis and driving hepatic–intestinal dysfunction

iMeta, EarlyView.
The pervasiveness of microplastic pollution poses a growing health risk, yet its long‐term metabolic consequences remain poorly defined. Here, we exposed mice to polyethylene terephthalate nanoparticle (NP) and combined histopathology, biochemistry, metabolomics, and metagenomics to resolve their interactions.
Yi Zhang, Zheng Lin, Runtong Huang, Yang Zhang, Lei Wang, Zan Fu, Chao Wang, Shuai Xiao, Heru Pramono, Kui Xu, Zhimin Xu, Yulong Yin   +11 more
wiley   +1 more source

The interactions between autophagy and immune in the liver-adipose-ovary circuit of polycystic ovary syndrome. [PDF]

Front Immunol
Nie G, Liu M, Yang L, Li C, Qu C, Wang J, Mei J, Wang Y, Han L, Zhang X, Wang Q.   +10 more
europepmc   +1 more source

A bioactive ginsenoside alleviates hepatocellular ferroptosis induced by oxidized phospholipid accumulation in nonalcoholic steatohepatitis

iMeta, EarlyView.
Schematic representation showing that 20 (S)‐Rg3 improves mouse NASH. 20(S)‐Rg3 reduces OxPLs levels and ameliorates ferroptosis in the liver of NASH mice. Mechanistically, 20(S)‐Rg3 activates SPOP. Meanwhile, SPOP attenuates the ATF3‐mediated transcriptional repression of NUPR1 by enhancing the K48‐linked ubiquitination of ATF3.
Yibo Zong, Guo Long, Tiantian Gu, Pan Huang, Yong Tian, Wenwu Xu, Xiheng Hu, Dazun Shi, Lizhi Lu, Tao Zeng   +9 more
wiley   +1 more source