Results 251 to 260 of about 399,223 (393)

Insulin Receptor Substrate 3 (IRS-3) and IRS-4 Impair IRS-1- and IRS-2-Mediated Signaling

open access: green, 2001
Kaku Tsuruzoe   +4 more
openalex   +1 more source

The hepatitis C virus core protein of genotypes 3a and 1b downregulates insulin receptor substrate 1 through genotype‐specific mechanisms† [PDF]

open access: bronze, 2007
Valerio Pazienza   +6 more
openalex   +1 more source

β-Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

open access: yesJournal of Neuroscience, 2009
Qiu-lan Ma   +12 more
semanticscholar   +1 more source

USP35 Acts as a Deubiquitinating Enzyme for ID3 to Promote Immune Escape in Colorectal Cancer

open access: yesAdvanced Science, EarlyView.
USP35 stabilizes ID3 expression by deubiquitinating the K2/K30 site, thereby upregulating PD‐L1 and promoting immune escape in colorectal cancer. IU1, an inhibitor of USP35 enzyme activity, has been shown to inhibit USP35, thereby accelerating ID3 degradation, enhancing CD8+ T cell killing, and reversing the immunosuppressive microenvironment ...
Wenxin Chen   +9 more
wiley   +1 more source

Sex differences in adipose insulin resistance are linked to obesity, lipolysis and insulin receptor substrate 1. [PDF]

open access: yesInt J Obes (Lond)
Arner P   +7 more
europepmc   +1 more source

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