Absence of down-regulation of the insulin receptor by insulin. A possible mechanism of insulin resistance in the rat [PDF]
, 1983 A. P. Walker, D. J. Flint
openalex +1 more source
Advanced Sensor Research, EarlyView.Implantable biosensors hold the promise to revolutionize the way disease diagnosis and progression during treatment are viewed. However, in the current state of art, their efficiency is limited by certain material challenges. Porous Silicon (pSi) is a viable material for in vivo monitoring of biomarkers, and its potential as an implantable biosensor is
Pritam Sharma +4 more
wiley +1 more source
INSULIN RESISTANCE (IR) IN TURNER SYNDROME (TS): DETECTION BY DIMINISHED IN VITRO RESPONSE OF ERYTHROCYTE PROGENITOR CELLS (EPC) TO INSULIN [PDF]
, 1984 Mitchell E. Geffner +4 more
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Dual Foreign Body Response Mitigation Strategies for Implantable Glucose Sensors
Advanced Sensor Research, EarlyView.The foreign body response negatively impacts the analytical lifetime of implantable glucose sensors due to a heightened immune response and deposition of collagen. While nitric oxide release has shown promise as a foreign body response mitigation strategy, improvement is limited by the duration of release.
Taron M. Bradshaw +9 more
wiley +1 more source
Detection of mutations in the insulin receptor gene in patients with insulin resistance by analysis of single-stranded conformational polymorphisms [PDF]
, 1992 Hyungjun Kim +12 more
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Advanced Sensor Research, EarlyView.This study deciphers the mechanism of enhanced glucose detection using multiwalled carbon nanotubes and nickel oxide stacks (MWCNTs/NiO/MWCNTs) on commercially available carbon paper electrodes. We demonstrate the role of MWCNTs where the defects enrich the electrocatalytic activity when they come in contact with the glucose molecule for its selective ...
Akshay Parab +6 more
wiley +1 more source
Heterogeneity Landscape of Circulating Tumor Cells in Clinical Utility
Advanced Therapeutics, EarlyView.This study reports the heterogeneity spectrum of circulating tumor cells. The factors involved in the spectrum promote CTCs to overcome barriers in the metastatic cascade but impact the clinical outcome of cancer patients. In summary, the heterogeneities in association with CTCs ultimately reduce patient survival and facilitate increasing mortality of ...
Md Kowsar Alam +5 more
wiley +1 more source
Cytokine Engineering Approaches for Regenerative Medicine
Advanced Therapeutics, EarlyView.Engineered cytokines represent a powerful strategy to promote tissue repair and regeneration by precisely modulating immune responses. This review highlights recent advances in cytokine engineering, including strategies to enhance half‐life, improve tissue and cell targeting, and control receptor signaling.
Shiyi Li, Wenhao You, Mikaël M. Martino
wiley +1 more source
Prediction Model for Insulin Resistance and Implications for MASLD in Youth: A Novel Marker, the Pediatric Insulin Resistance Assessment Score. [PDF]
Yonsei Med JSong K +8 more
europepmc +1 more source