Results 91 to 100 of about 271,085 (312)
From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion
Cell Reports, 2018 Summary: Glucose-stimulated insulin secretion from islet β cells is mediated by KATP channels. However, the role of non-KATP K+ channels in insulin secretion is largely unknown. Here, we show that a non-KATP K+ channel, KCNH6, plays a key role in insulin
Jin-Kui Yang +25 more
doaj
Advanced Materials, EarlyView.Adipocyte membrane‐coated nanoparticles loaded with rosiglitazone in hydrogel offer an alternative approach to conventional obesity treatments. This system selectively targets adipocytes, inducing lipolysis by activating chaperone‐mediated autophagy through mild photothermal stimulation.
Jaehyun Choi +8 more
wiley +1 more source
Control of insulin secretion during fasting hyperglycemia in adult diabetics and in nondiabetic subjects during infusion of glucose [PDF]
, 1969 Charles J. Goodner +2 more
openalex +1 more source
Photonic Nanomaterials for Wearable Health Solutions
Advanced Materials, EarlyView.This review discusses the fundamentals and applications of photonic nanomaterials in wearable health technologies. It covers light‐matter interactions, synthesis, and functionalization strategies, device assembly, and sensing capabilities. Applications include skin patches and contact lenses for diagnostics and therapy. Future perspectives emphasize AI‐
Taewoong Park +3 more
wiley +1 more source
Nature Communications, 2016 Dysfunction in insulin secretion is a main driver of type 2 diabetes development. Here the authors monitor phosphoproteome modulation in cells stimulated with glucose and treated with drugs affecting glucose-mediated insulin secretion to reveal ...
Francesca Sacco +7 more
doaj +1 more source
Regulation of Insulin Secretion by Short Chain Fatty Acids [PDF]
, 1968 W Montague, K. W. Taylor
openalex +1 more source
Advanced Materials, EarlyView.This work has developed a dual enzyme‐mimicking and ultrasound‐responsive Nb2C‐Pt@HA‐PEG nanozyme. ROS‐eliminating and antiinflammatory capability of Nb2C‐Pt@HA‐PEG under US irradiation are demonstrated on macrophages and endothelial cells in vitro. Nb2C‐Pt@HA‐PEG‐mediated sonocatalytic therapy exerts an outstanding anti‐atherosclerosis efficacy by ...
Qianqian Bai +6 more
wiley +1 more source
Effects of neutral red and imidazole upon insulin secretion [PDF]
, 1968 Willy Malaisse +2 more
openalex +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
Advanced Materials, EarlyView.NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang +25 more
wiley +1 more source
Insulin Secretion in Sheep with Autotransplants of the Pancreas [PDF]
, 1969 D. W. BEAVEN +4 more
openalex +1 more source