Results 151 to 160 of about 265,255 (314)
The mechanism of insulin secretion after oral glucose administration [PDF]
H Hommel, Urs Fischer
openalex +1 more source
This study reveals a new mechanism by which PDIA3P1 regulates the progression of esophageal squamous cell carcinoma (ESCC). PDIA3P1 upregulates the expression of GLUT1 and HK2, promoting glycolysis and lactate production. Lactate upregulates the lactylation level of histone H4K8 and activates the transcription of target gene BMP7, ultimately ...
Tao Huang+13 more
wiley +1 more source
Low-dose quinine targets KCNH6 to potentiate glucose-induced insulin secretion. [PDF]
Xiong FR, Zhu JJ, Zhu XR, Lu J, Yang JK.
europepmc +1 more source
The mechanism of insulin secretion after oral glucose administration [PDF]
Urs Fischer+3 more
openalex +1 more source
Senescent mesenchymal stromal cells (MSCs) drive age‐related osteoporosis (A‐OP) via adipogenic bias. Resveratrol, selected from transcriptome‐identified core genes, is delivered locally using GelMA‐chitosan hydrogel‐functionalised titanium implants. In A‐OP microenvironments, the hydrogel enables the sustained release of resveratrol, which reverses ...
Wuzhe Fan+12 more
wiley +1 more source
Pyruvate kinase modulates the link between β-cell fructose metabolism and insulin secretion. [PDF]
Murao N+8 more
europepmc +1 more source
The effect of N-acylglucosamines on the biosynthesis and secretion of insulin in the rat [PDF]
S. J. H. Ashcroft+2 more
openalex +1 more source
Astrocytic ET‐1 System Determines Microglia Phenotype Following Spinal Cord Injury
The study reveals that astrocytic ET‐1 system is solely activated by thrombin following SCI via RhoA/NF‐κB and MAPKs/NF‐κB signal pathway. The release of astrocytic ET‐1 drives microglia polarization toward M1 phenotype through YAP signaling via ETA and ETB receptors.
Bingqiang He+11 more
wiley +1 more source
Dexmedetomidine suppresses glucose-stimulated insulin secretion in pancreatic β-cells. [PDF]
Kusunoki M+5 more
europepmc +1 more source