Results 261 to 270 of about 342,036 (317)

[Insulin secretion in non-insulin-dependent diabetes].

Journees annuelles de diabetologie de l'Hotel-Dieu, 1991
Turner, R, Clark, A, Levy, J, Hattersley, A, Cook, J   +4 more
openaire   +3 more sources

Assessing the rate dependence of the first phase of glucose-stimulated insulin secretion: dynamic perifusion studies with isolated human pancreatic islets. [PDF]

Am J Physiol Endocrinol Metab
Buchwald P, Chuang ST, Watts B, Alcazar O.   +3 more
europepmc   +1 more source

Branched-chain α-keto acids impair glucose-stimulated insulin secretion in pancreatic β-cells under diabetes by reactivating the LDHA-lactate axis. [PDF]

Nat Commun
Lin H, Ho MYM, Wang B, Mansoori S, Yang Y, Wang W, So PK, Xu A, Yang S, Chang J, Man AMH, Piao H, Gao C, Siu PMF, Li X, Cheng KKY.   +15 more
europepmc   +1 more source

Acute activation of Gq-signaling in islet macrophages inhibits β-cell insulin secretion through AMPK-sphingolipid axis

Singh S, Kumar A, Paul S, Sarkar M, Duraisamy S, Yadav H, Kuldeep S, Bhaumik S, Prajapati KK, Thaleshwari S, Gargya A, Santra T, Amit S, Parihar R, Misra SK, Zafar H, Barella LF, Allimuthu D, Pydi SP.   +18 more
europepmc   +1 more source

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Insulin Secretion in Kwashiorkor

The Journal of Clinical Endocrinology & Metabolism, 1972
ABSTRACT Basal plasma insulin levels were normal in kwashiorkor, but their response to oral glucose was impaired. As a result of the impaired insulin secretion, the glucose tolerance was abnormal and there was no reduction in plasma α-amino nitrogen levels.
K S, Jaya Rao, N, Raghuramulu
openaire   +2 more sources

Somatostatin and insulin secretion

Metabolism, 1978
Abstract The inhibitory effect of somatostatin was first demonstrated in in vitro studies in rat pituitary cell cultures. Thus, initially, its action on the release of pituitary hormones in man and animals was the main focus of interest. While investigating the effect of somatostatin on growth hormone release we, as well as other groups, made the ...
S, Efendic, P E, Lins, R, Luft
openaire   +2 more sources

Aging and insulin secretion

American Journal of Physiology-Endocrinology and Metabolism, 2003
Glucose tolerance progressively declines with age, and there is a high prevalence of type 2 diabetes and postchallenge hyperglycemia in the older population. Age-related glucose intolerance in humans is often accompanied by insulin resistance, but circulating insulin levels are similar to those of younger people. Under some conditions of hyperglycemic
Annette M, Chang, Jeffrey B, Halter
openaire   +2 more sources

The cytoskeleton and insulin secretion

Diabetes/Metabolism Reviews, 1986
One of the central, unresolved problems in our understanding of insulin secretion is the way in which stimulus recognition and its associated metabolic events are translated into the mechanical processes of insulin-storage granule movement and extrusion from the cells by exocytosis. In the present article we have examined the structural organization of
S L, Howell, M, Tyhurst
openaire   +2 more sources

Insulin secretion in hyperlipoproteinemias

Acta Diabetologica Latina, 1974
Insulin secretion has been evaluated after oral glucose loading and other stimuli (tolbutamide, glucagon, arginine and i.v. glucose) in a group of 3 patients with familial hyperchylomicronemia (Fredrickson’s Type I), 33 patients with primary hypercholesterolemia (Fredrickson’s Type II) and 89 patients with endogenous hypertriglyceridemia.
A. Tiengo, MUGGEO, Michele, D. Fedele, E. Marchiori, G. Crepaldi   +4 more
openaire   +3 more sources

Insulin Secretion in Obesity

New England Journal of Medicine, 1967
ALTHOUGH hyperinsulinemia has been well established in obese subjects1 , 2 only some demonstrate abnormalities of glucose tolerance. It has been suggested that the ability of the obese subject to maintain normal glucose tolerance is a function of B-cell reserve, implying that insulin secretory rates and plasma insulin levels would be higher in obese ...
R A, Kreisberg, B R, Boshell, J, DiPlacido, R F, Roddam   +3 more
openaire   +2 more sources