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Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the
Aarti Mathur, Steven K Libutti
exaly +5 more sources
AbstractA 38-year-old female presented with recurrent episodes of hypoglycemia for 5 years. On 72-h fast test, critical sample biochemistry was suggestive of endogenous hyperinsulinemic hypoglycemia. Both constrast-enhanced computed tomography and 68Ga-DOTATATE positron emission tomography/computerized tomography (PET/CT) revealed no pancreatic lesion ...
Robin Garg +3 more
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Localization of Insulinomas [PDF]
Intraoperative ultrasonography is more sensitive than preoperative and other intraoperative techniques for localizing insulinoma.Retrospective review.A tertiary referral center.All patients with a biochemical diagnosis of organic hyperinsulinism who were referred to University of California, San Francisco, from 1975 to 1998.Sensitivities of the ...
M P, Boukhman +5 more
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Authors present the history of a 56-year-old man who was evaluated for recurrent epigastrial pain. Clinical investigation revealed a 4-cm tumor in the head of the pancreas and a solitary liver metastasis. Pathological examination of the surgically excised pancreatic tumor indicated a moderately differentiated neuroendocrine carcinoma and Ki-67 ...
Miklós, Tóth +5 more
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Neurofibromatosis and insulinoma [PDF]
AbstractA 45-year-old man with neurofibromatosis presented with recurrent seizures due to hypoglycaemia caused by an insulinoma. The attacks were abolished after the successful removal of the insulinoma. This probably represents another example of the association between neurofibromatosis and a tumour consisting of cells with amine-precursor-uptake and
Fung, JWK, Lam, KSL
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According to official statistics, malignant insulinomas account for a small fraction of gastroenteropathic endocrine neoplasms, the majority of insulinomas being essentially benign tumours. This paper reports a clinical case of malignant insulin-producing neuroendocrine tumour of the pancreas tail in a 28 year-old woman.
E A, Troshina +5 more
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A B S T R A C TInsulinoma is a functional neuroendocrine neoplasm consisting of insulin-producingcells, which produce insulin uncontrollably, causing a hypoglycemic syndrome. TheHypoglycemic syndrome is a result of hyperinsulinemia which causes adrenergicsymptoms and neuroglycopenia.
Ria Yuniarti, null Suly Auline
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Abstract Background Insulinomas are rare tumours. Their clinical presentation, localization techniques and operative management were reviewed. Methods An electronic search of the Medline, Embase and Cochrane databases was undertaken ...
O N, Tucker, P L, Crotty, K C, Conlon
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El insulinoma es el tumor neuroendocrino del páncreas más frecuente. Se presenta el caso de un paciente de 54 años de edad. La sintomatología conocida por la disminución severa de la glicemia en el sistema nervioso central, el diagnostico se basó en la evidencia de hipoglicemia, asociado a niveles elevados de insulina.
Herrera-Favian, Pedro Roberto +2 more
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Dominika, Kochan-Olszewska +2 more
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