Results 1 to 10 of about 29,307 (202)
Elevated blood levels of liver-expressed antimicrobial peptide 2 in patients with insulinoma and its expression in insulinomas [PDF]
ObjectiveMost patients with insulinoma are overweight or obese. Ghrelin levels in insulinoma have been linked to both obesity and hyperinsulinemia. Liver-expressed antimicrobial peptide 2 (LEAP2), a novel hormone and endogenous antagonist of the ghrelin ...
Jia-Lei Zhang +9 more
doaj +2 more sources
A 38-year-old female presented with recurrent episodes of hypoglycemia for 5 years. On 72-h fast test, critical sample biochemistry was suggestive of endogenous hyperinsulinemic hypoglycemia.
Robin Garg +3 more
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Case Report: Diazoxide-induced diabetic ketoacidosis in a patient with insulinoma [PDF]
Definitive management of insulinoma is challenging as curative surgery is associated with a considerable risk of morbidity and mortality. The successful long-term use of diazoxide for patients diagnosed with insulinoma has been described, but rarely, the
Run Ting Chin +3 more
doaj +2 more sources
Insulinoma is a rare neuroendocrine tumor with an incidence of 4 per 1 million persons per year, which may occur as a unifocal sporadic event in patients without an inherited syndrome or as a part of multiple endocrine neoplasia type 1. Key neuroglycopenic and hypoglycemic symptoms in conjunction with biochemical proof establish the diagnosis. Once the
Kimberly, Vanderveen, Clive, Grant
openaire +4 more sources
Insulinoma - review of characteristics, diagnosis and treatment
Introduction and purpose: Insulinoma is one of a group of pancreatic neuroendocrine neoplasms (NENs). This tumor has its origin in the β cells of the pancreatic islets, which are responsible for the production of insulin.
Klaudia Sapuła +6 more
doaj +1 more source
Insulinoma: Spectrum of Clinicopathological Features in a Tertiary Center
Introduction:Insulinoma is the most common functional neuroendocrine tumor of the pancreas. There are different methods for the preoperative localization of insulinoma, such as Computed Tomography (CT) scan, Magnetic Resonance Imaging and Endoscopic ...
Nooshin Shirzad +3 more
doaj +1 more source
Authors present the history of a 56-year-old man who was evaluated for recurrent epigastrial pain. Clinical investigation revealed a 4-cm tumor in the head of the pancreas and a solitary liver metastasis. Pathological examination of the surgically excised pancreatic tumor indicated a moderately differentiated neuroendocrine carcinoma and Ki-67 ...
Miklós, Tóth +5 more
openaire +2 more sources
The insulinoma as a diagnostically and therapeutically challenging neoplasm
Introduction and purpose An insulinoma is the most common neuroendocrine tumor of a pancreas. This tumor produces insulin, which in excess causes hypoglycemic attacks, provoked by hunger or physical effort.
Paulina Oleksa +5 more
doaj +1 more source
A B S T R A C TInsulinoma is a functional neuroendocrine neoplasm consisting of insulin-producingcells, which produce insulin uncontrollably, causing a hypoglycemic syndrome. TheHypoglycemic syndrome is a result of hyperinsulinemia which causes adrenergicsymptoms and neuroglycopenia.
de Herder, W.W. +2 more
+7 more sources
Successful Endoscopic Ultrasound-Guided Alcohol Ablation of Sporadic Insulinoma Using Three-Dimensional Targeting (with Video) [PDF]
Surgical resection is considered the standard of care in the management of symptomatic insulinoma. In this video, we describe the successful management of a symptomatic insulinoma by using linear array endoscopic ultrasound (EUS)-guided ethanol ablation ...
Guru Trikudanathan +2 more
doaj +1 more source

