Results 21 to 30 of about 34,487 (256)

Periodic limb movement disorder: A novel presentation of insulinoma

Annals of Movement Disorders, 2018
Hypoglycemia because of insulinoma can mimic many neurological disorders including movement disorders during sleep. We present a 54-year-old woman who presented with features typical of periodic limb movement disorder and on detailed evaluation was found
Deepa Dash, Shaily Singh, Manjari Tripathi   +2 more
doaj   +1 more source

Canine insulinoma as a model for human malignant insulinoma research: Novel perspectives for translational clinical studies

Translational Oncology, 2022
Insulinomas are considered rare indolent neuroendocrine neoplasms in human medicine, however when metastases occur no curative treatment is available thus, novel therapies are needed.
Ylenia Capodanno, Barbara Altieri, Richard Elders, Annamaria Colao, Antongiulio Faggiano, Joerg Schrader   +5 more
doaj   +1 more source

Genetic obesity increases pancreatic expression of mitochondrial proteins which regulate cholesterol efflux in BRIN-BD11 insulinoma cells [PDF]

, 2019
Pancreatic β-cells are sensitive to fluctuations in cholesterol content, which can damage the insulin secretion pathway, contributing to the aetiology of type 2 diabetes mellitus.
Caridis, Anna Maria, Dolan, Sharron, Graham, Annette, Lightbody, Richard J., Tarlton, Jamie M.R.   +4 more
core   +1 more source

Adult-onset hyperinsulinaemic hypoglycaemia in clinical practice: diagnosis, aetiology and management

Endocrine Connections, 2017
Objective: In adults with hyperinsulinaemic hypoglycaemia (HH), in particular those with insulinoma, the optimal diagnostic and management strategies remain uncertain.
Benjamin G Challis, Andrew S Powlson, Ruth T Casey, Carla Pearson, Brian Y Lam, Marcella Ma, Deborah Pitfield, Giles S H Yeo, Edmund Godfrey, Heok K Cheow, V Krishna Chatterjee, Nicholas R Carroll, Ashley Shaw, John R Buscombe, Helen L Simpson   +14 more
doaj   +1 more source

Novel prokaryotic expression of thioredoxin-fused insulinoma associated protein tyrosine phosphatase 2 (IA-2), its characterization and immunodiagnostic application [PDF]

, 2016
Background The insulinoma associated protein tyrosine phosphatase 2 (IA-2) is one of the immunodominant autoantigens involved in the autoimmune attack to the beta-cell in Type 1 Diabetes Mellitus.
A Trabucchi, A Trabucchi, A Trabucchi, A Villalba, A Villalba, A Westerlund-Karlsson, Adriana Victoria Sabljic, AG Krochik, AL Notkins, Aldana Trabucchi, BD Spangler, Bruno David Rovitto, C Levy-Marchal, C Tiberti, C Torn, CA Baer, CC Richardson, CF Verge, D Barford, DU Rabin, DU Rabin, E Bonifacio, E Bonifacio, E Kawasaki, EA Gale, Edgardo Poskus, ELD Harlow, ER LaVallie, ER LaVallie, ET Mambetisaeva, Expert Committee on the Diagnosis and Classification of Diabetes Mellitus, F Baneyx, F Sodoyez-Goffaux, G Hannig, GS Eisenbarth, H Goetz, H Mziaut, H Mziaut, H Shägger, H Xie, I Kikkas, J Sambrook, J Seissler, J Suckale, JA Berzofsky, JA Berzofsky, JA Dromey, JC Sodoyez, JM Gonzalez-Buitrago, JM Wenzlau, JP Palmer, K Lobner, KT Elvers, L Castano, LL Guerra, Luciano Lucas Guerra, M Hawa, M Knip, M Masuda, M Solimena, M Trajkovski, M Trajkovski, MA Payton, ML Papouchado, ML Papouchado, MP Sica, MS Lan, MS Lan, Natalia Inés Faccinetti, NG Morgenthaler, O Pines, P Tompa, PD Burbelo, PJ Bingley, PZ Zimmet, R Gianani, R Turner, RD Hoffman, RR Stumpo, Ruben Francisco Iacono, S Chen, S Krause, S Schubert, S Torii, Silvina Noemí Valdez, SJ Kim, SLBP Thrower, SN Valdez, SN Valdez, T Ort, T Tuomi, VN Uversky, WA Hagopian, X Jia, X Palomer, Z Zhao   +95 more
core   +5 more sources

Insulinoma: presentación neuro psiquiátrica, caso clínico y revisión de la literatura

Revista Médica Clínica Las Condes, 2022
Resumen: Antecedentes: el insulinoma es un tumor infrecuente que desencadena cuadros de hipoglicemia manifestados por los clásicos síntomas vegetativos y neuroglucopénicos.
Luis Ángel Rodríguez, Franco M. Nazario   +1 more
doaj   +1 more source

Localization of Insulinomas [PDF]

Archives of Surgery, 1999
Intraoperative ultrasonography is more sensitive than preoperative and other intraoperative techniques for localizing insulinoma.Retrospective review.A tertiary referral center.All patients with a biochemical diagnosis of organic hyperinsulinism who were referred to University of California, San Francisco, from 1975 to 1998.Sensitivities of the ...
M P, Boukhman, J M, Karam, J, Shaver, A E, Siperstein, A A, DeLorimier, O H, Clark   +5 more
openaire   +2 more sources

Novel insights into pancreatic β-cell glucolipotoxicity from real-time functional analysis of mitochondrial energy metabolism in INS-1E insulinoma cells. [PDF]

, 2013
Work in our lab is supported by the Medical Research Council [New Investigator Research Grant G1100165 to CA] and Plymouth University [PhD studentship to JB] The final version of record is available at http://www.biochemj.org/bj/456/bj4560417.htmHigh ...
Affourtit, C, Barlow, J
core   +2 more sources

Expression of the neural cell adhesion molecule NCAM in endocrine cells [PDF]

, 1989
We examined the expression of the neural cell adhesion molecule NCAM in a number of endocrine tissues of adult rat and in an endocrine tumor cell line. NCAM was found by immunoelectron microscopy to be present on the surface of all endocrine cells in the
Aletsee-Ufrecht, M. C., Grant, N., Gratzl, Manfred, Langley, O. K.   +3 more
core   +1 more source

A novel diagnostic model for insulinoma

Discover Oncology, 2022
The aim is to describe a simple and feasible model for the diagnosis of insulinoma. This retrospective study enrolled 37 patients with insulinoma and 44 patients with hypoglycemia not due to insulinoma at the First Affiliated Hospital of Guangxi Medical ...
Feng Wang, Zhe Yang, XiuBing Chen, Yiling Peng, HaiXing Jiang, ShanYu Qin   +5 more
doaj   +1 more source