Results 51 to 60 of about 32,237 (258)
ABSTRACT The percomorph fish clade Gobioidei is a suborder that comprises over 2200 species distributed in nearly all aquatic habitats. To understand the genetics underlying their species diversification, we sequenced and annotated the genome of the loach goby, Rhyacichthys aspro, an early‐diverging group, and compared it with nine additional Gobioidei
Tzi‐Yuan Wang+10 more
wiley +1 more source
Prokaryotic expression and characterization of the heterodimeric construction of ZnT8 and its application for autoantibodies detection in diabetes mellitus [PDF]
Background: In the present work we described the recombinant production and characterization of heterodimeric construction ZnT8-Arg-Trp325 fused to thioredoxin using a high-performance expression system such as Escherichia coli.
Bombicino, Silvina Sonia+8 more
core +4 more sources
Insulinoma with focal hepatic lesions: malignant insulinoma? [PDF]
Insulinoma is a rare tumour that is malignant in only 10% of cases. We report a case of insulinoma in a 59-year-old woman, associated with focal liver lesions, which raised the suspicion of malignancy of a pancreatic tumour. Enucleation of the insulinoma was performed with wedge resection of one hepatic nodule.
Yossra Zidi-Mouaffek+3 more
openaire +3 more sources
Ketotic Hypoglycaemia Following Sleeve Gastrectomy
ABSTRACT Post‐bariatric surgery hypoglycaemia is typically mediated by hyperinsulinaemia, although the exact mechanisms are incompletely understood. Two cases of non‐insulin mediated, ketotic hypoglycaemia following sleeve gastrectomy are presented. After fasting for 40 and 65 h, respectively, both patients developed symptomatic hypoglycaemia, with ...
Jinwen He+3 more
wiley +1 more source
O insulinoma é doença rara que cursa com sintomas episódicos neuroglicopênicos e/ou adrenérgicos. Descrevemos o caso de uma paciente de 36 anos, que estava sendo tratada por crises convulsivas parciais complexas há 4 anos sem melhora do quadro ...
Carlos Alexandre Twardowschy+3 more
doaj +1 more source
ABSTRACT Objective This study aimed to evaluate the clinical characteristics, diagnostic approaches, and treatment outcomes of insulinoma patients from diverse regions across the country. We conducted a retrospective analysis of medical records from 76 adult patients diagnosed with insulinoma between 2018 and 2023 at 15 medical centres.
Şenay Topsakal+24 more
wiley +1 more source
Insulinoma: presentación neuro psiquiátrica, caso clínico y revisión de la literatura
Resumen: Antecedentes: el insulinoma es un tumor infrecuente que desencadena cuadros de hipoglicemia manifestados por los clásicos síntomas vegetativos y neuroglucopénicos.
Luis Ángel Rodríguez+1 more
doaj
La hipoglucemia persistente causada por un insulinoma es una patología poco frecuente que requiere un diagnóstico bioquímico y localización regional del tumor ante la sospecha para un tratamiento adecuado.
Isabel Pulgar-Sedó+3 more
doaj +1 more source
El insulinoma es el tumor neuroendocrino del páncreas más frecuente. Se presenta el caso de un paciente de 54 años de edad. La sintomatología conocida por la disminución severa de la glicemia en el sistema nervioso central, el diagnostico se basó en la evidencia de hipoglicemia, asociado a niveles elevados de insulina.
Herrera-Favian, Pedro Roberto+2 more
openaire +4 more sources
Insulinomas are considered rare indolent neuroendocrine neoplasms in human medicine, however when metastases occur no curative treatment is available thus, novel therapies are needed.
Ylenia Capodanno+5 more
doaj