Results 51 to 60 of about 14,705 (155)
To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine neoplasia type 1 (MEN1) using a large nationwide cohort. ABSTRACT Objective To describe surgical indications, procedures and outcomes in patients operated for Zollinger‐Ellison syndrome (ZES) in multiple endocrine ...
Sébastien Gaujoux +27 more
wiley +1 more source
Clinical paradox: insulinoma in a patient with type 1 diabetes mellitus
Insulinoma is a rare neuroendocrine tumor occurring from beta-cells of the pancreas. Тhe diagnosis of insulinoma may be difficult, especially in patients with concomitant diabetes mellitus.
A. S. Ametov +5 more
doaj +1 more source
O insulinoma é doença rara que cursa com sintomas episódicos neuroglicopênicos e/ou adrenérgicos. Descrevemos o caso de uma paciente de 36 anos, que estava sendo tratada por crises convulsivas parciais complexas há 4 anos sem melhora do quadro ...
Carlos Alexandre Twardowschy +3 more
doaj +1 more source
Impact of screening programmes for type 1 diabetes in youth: A systematic review and meta‐analysis
Abstract Aim To evaluate the impact of anti‐islet antibody (IAb) screening on the general population and first‐degree relatives (FDRs)/high‐risk individuals and evidence‐based follow‐up modalities. Methods We performed this review through systematic searches of PubMed, EMBASE, Cochrane Library, Web of Science, ClinicalTrials.gov and International ...
Roberto Franceschi +24 more
wiley +1 more source
En este artículo presentamos un caso clínico de tumor funcional de células ß o insulinoma, así como los puntos más relevantes para su diagnóstico y tratamiento.
Li Ding, Qing He, Ming Liu
+7 more sources
Abstract A 61‐year‐old man visited our hospital with a sudden onset of polydipsia and polyuria occurring 5 days prior, accompanied by a 5‐kg weight loss. A month prior, his glycated hemoglobin level was 6.2%. Precisely 8 days before the first visit, he had a fever, and hyperglycemic symptoms began shortly thereafter.
Megumi Sato +6 more
wiley +1 more source
ABSTRACT Pancreatic neuroendocrine tumors (PanNETs) are increasingly diagnosed, reflecting greater clinical awareness, improved imaging, and revised classification. This review summarizes evidence on epidemiology, diagnostic workup, and endoscopic ultrasound (EUS)–guided management of PanNETs, encompassing diagnostic evaluation, tissue acquisition, and
Angelo Bruni +7 more
wiley +1 more source
Jagn1 Is Induced in Response to ER Stress and Regulates Proinsulin Biosynthesis. [PDF]
The Jagn1 protein was indentified in a SILAC proteomic screen of proteins that are increased in insulinoma cells expressing a folding-deficient proinsulin.
Courtney Nosak +7 more
doaj +1 more source
ABSTRACT Introduction This narrative review explores the epidemiological evidence and potential underlying pathophysiological defects underlying the disproportionately greater risk of Type 2 diabetes (T2D) and cardiometabolic disease in people of South Asian and African Caribbean ancestry compared with White Europeans.
Daniel J. Cuthbertson +6 more
wiley +1 more source
El insulinoma es un tumor neuroendocrino poco frecuente, con una incidencia de 1 a 4 casos por millón de habitantes/año. Se desarrolla de forma esporádica en pacientes sin síndrome hereditario o como una neoplasia endocrina múltiple tipo 1. El diagnóstico se establece en base al hallazgo de síntomas neuroglucopénicos e hipoglucémicos y por pruebas ...
Berdejo, José +2 more
openaire +3 more sources

