Results 51 to 60 of about 18,899 (217)
A Case Report of Insulinoma Treated for Refractory Seizures
Journal of Medical Sciences and Health, 2018 Insulinoma is a functional endocrine tumor of the pancreas that secretes insulin. Insulinoma comprises 25% of the pancreatic endocrine tumors. Patients may have heterogeneous presentation of symptoms varying from mild autonomic symptoms to severe ...
Shreemit Maheshwari +4 more
doaj
Management of malignant insulinoma [PDF]
Clinical and Translational Oncology, 2013 Malignant insulinoma is an infrequent functional endocrine tumor of the pancreas. Adequate therapy is a demanding challenge for oncologists and endocrinologists.To evaluate the results of multidisciplinary management of malignant insulinoma.Retrospective review of patients with malignant insulinoma treated from 1995 to 2011.Seven patients with ...
Juan Carlos Ferrer-García +8 more
openaire +4 more sources
Journal of Neuroendocrinology, EarlyView.Abstract Non‐functioning pancreatic neuroendocrine tumors (NF‐pNETs) significantly contribute to the premature death of multiple endocrine neoplasia type 1 (MEN1) patients. Reliable prognostic markers are not yet available. MicroRNAs (miRNA) and long‐non‐coding (lnc) RNAs, transported by extracellular vesicles, are emerging as new prognostic tools ...
Jerena Manoharan +12 more
wiley +1 more source
A case of insulinoma with hypoglycemia that was better managed with lanreotide than octreotide
Clinical Case Reports, 2021 Long‐acting somatostatin analogs, including lanreotide slow release (LAN‐SR) and octreotide long‐acting release (OCT‐LAR), can improve hypoglycemia in insulinoma. LAN‐SR may be more beneficial in some patients with insulinoma than OCT‐LAR.
Keiko Yamaoka +14 more
doaj +1 more source
Beyond fluorodeoxyglucose: Molecular imaging of cancer in precision medicine
CA: A Cancer Journal for Clinicians, EarlyView.Abstract Cancer molecular imaging is the noninvasive visualization of a process unique to or altered in neoplasia, such as proliferation, glucose metabolism, and receptor expression, which is relevant to patient management. Several molecular imaging modalities are now available, including magnetic resonance, optical, and nuclear imaging.
Malik E. Juweid +6 more
wiley +1 more source
Artesunate induces ferroptosis in osteosarcoma through NCOA4‐mediated ferritinophagy
The FASEB Journal, Volume 39, Issue 7, 15 April 2025.The graphic abstract of this research, and the detailed description are in the abstract. Abstract Osteosarcoma (OS) is a prevalent primary malignant bone tumor that lacks effective therapeutic interventions. Artesunate (ART) has been proved to have remarkable treatment effects on severe malaria and anti‐tumor properties. This study aimed to investigate
Rui Huang +5 more
wiley +1 more source
Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells
FEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki +5 more
wiley +1 more source
Characterization of the Pancreatic Neuroendocrine Neoplasm Immune Microenvironment
Cancer Medicine, Volume 14, Issue 7, April 2025.Enhancements in the creation of animal models that most accurately represent the aggressive types of pancreatic neuroendocrine neoplasms are necessary to create therapeutic protocols that combine immunotherapies with other medication classes to help patients with metastatic disease recover or respond to treatment more durably. Tumor microenvironment is
Filipe Reis Neves +3 more
wiley +1 more source