Results 101 to 110 of about 39,252 (190)

Genomic Sequencing and Analysis of New Variants of Enzootic Nasal Tumour Virus Type 2 Revealed Recombination Events between Different Sublineages

open access: yesVeterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The strains from sublineages 1.5 and 1.2 may be promoting the emergence of new strains of ENTV‐2 in China. Recombination drives ENTV‐2's rapid evolution . ABSTRACT In recent years, multiple regions in China have experienced an increase in the occurrence of enzootic nasal tumour virus type 2 (ENTV‐2) infections. This research highlights the initial full
Yong Pan   +5 more
wiley   +1 more source

T‐bet Fate Mapping Reveals Gestational Stage‐Specific Transcriptional Adaptation of Decidual NK Cells

open access: yesAmerican Journal of Reproductive Immunology, Volume 95, Issue 3, March 2026.
ABSTRACT Problem Natural killer (NK) cells are critical regulators of immune balance at the maternal–fetal interface. T‐bet (Tbx21) is a key transcription factor shaping NK cell effector functions, yet its role in decidual NK (dNK) cell adaptation across gestation remains unclear.
Mona A. Mohamed   +6 more
wiley   +1 more source

HIV Dynamics and Integrase Inhibitors

open access: yesAntiviral Chemistry and Chemotherapy, 2009
The integrase inhibitor (INI) raltegravir has shown promising results in clinical trials to date, reducing second phase HIV RNA levels by 70% in comparison with standard regimens. These trial results have been limited by the 50 copies/ml detection limit of the HIV RNA assay and have not investigated the effect of an INI regimen on levels of latently ...
openaire   +2 more sources

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

open access: yesThe FEBS Journal, Volume 293, Issue 5, Page 1285-1296, March 2026.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source

Introns as Protective Buffers Against Transposable Elements Invasion During Genome Gigantism in a Newt

open access: yesGenes to Cells, Volume 31, Issue 2, March 2026.
In the giant Pleurodeles waltl genome, introns serve as “structural buffers,” absorbing transposable elements (TEs) to protect coding exons. While this enables “gene body inflation,” persistent TE accumulation eventually leads to transcriptional silencing and functional collapse, or “burst,” of the gene architecture.
Kazuto Bou, Kiyokazu Agata
wiley   +1 more source

Exploring the impact of baseline and on‐treatment variables on durability of responses to fostemsavir through weeks 96 and 192 in the phase 3 BRIGHTE study

open access: yesHIV Medicine, Volume 27, Issue 3, Page 386-396, March 2026.
Abstract Objectives The gp120‐directed attachment inhibitor fostemsavir was effective in people with multidrug‐resistant (MDR) HIV‐1 in the BRIGHTE study. Understanding factors associated with virologic response can help clinicians optimize treatment and identify individuals for fostemsavir‐based regimens.
M. Gartland   +8 more
wiley   +1 more source

Late diagnosis of paediatric HIV infection in high‐income countries: Lessons from the HIV Perinatal Virtual Clinic

open access: yesHIV Medicine, Volume 27, Issue 3, Page 477-484, March 2026.
Abstract Introduction Timely diagnosis of HIV in children remains a challenge in all settings including low‐prevalence, high‐income countries (HIC). We aimed to characterize the prevalence of late diagnosis, and prior missed diagnostic opportunities among new presentations of paediatric HIV in HIC referred to an international Perinatal Virtual Clinic ...
Carolina Curto   +8 more
wiley   +1 more source

Antimicrobial Resistance in Salmonella Across Aquaculture, Seafood and Related Aquatic Environments: A Scoping Review With Exploratory Textual Analysis

open access: yesReviews in Aquaculture, Volume 18, Issue 2, March 2026.
This scoping review with textual analysis maps antimicrobial resistance in Salmonella across aquaculture, seafood, and related aquatic environments. Across 93 studies, recurrent MDR patterns suggest sentinel serotypes (S. Typhimurium, S. Newport) and a minimal antimicrobial susceptibility testing (AST) panel to guide matrix‐stratified One Health ...
Cristiane Coimbra de Paula   +8 more
wiley   +1 more source

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