Processing of viral DNA by retroviral integrase leaves a dinucleotide single-strand overhang in the unprocessed strand. Previous studies have stressed the importance of the 5' single-stranded (ss) tail in the integration process.
JORGE VERA +3 more
doaj
Integrase-On-Demand: bioprospecting integrases for targeted genomic insertion of genetic cargo. [PDF]
McClain HM +8 more
europepmc +1 more source
A new-engineered integrative tool to target the terminal compartment of the Streptomyces chromosome. [PDF]
Delhaye N +5 more
europepmc +1 more source
Viruses Previously Classified as CRF146_BC, a Circulating Recombinant Form of HIV-1 Recently Reported in Brazil, Represent Different Recombinant Forms, One of Which Is Circulating in Spain. [PDF]
Donoso A +17 more
europepmc +1 more source
Gene-sized editing for the therapy of genetic diseases. [PDF]
Padureanu T +3 more
europepmc +1 more source
Anti-HIV-1 Activity of the Integrase Strand Transfer Inhibitor ACC017. [PDF]
Ma MD +8 more
europepmc +1 more source
Plasmid2MC: efficient cell-free generation of high-purity minicircle DNA for genome editing in mammalian cells. [PDF]
Oliynyk RT +3 more
europepmc +1 more source
Recent Developments in HIV Antivirals: The Prospect of Prophylactic Drugs to Change the Pandemic. [PDF]
Brüssow H.
europepmc +1 more source

