DNA sequence heterogeneity in Fim tyrosine‐integrase recombinase‐binding elements and functional motif asymmetries determine the directionality of the fim genetic switch in Escherichia coli K‐12 [PDF]
Matthew P. McCusker +2 more
openalex +1 more source
Bee products as alternatives in the treatment of viral infections
Abstract Medicines used in the treatment of viral infections usually reduce symptoms. There is a need to develop drugs that inhibit the viruses and do not merely relieve the symptoms. Natural bee products possess many pharmacological properties and are widely used in folk medicine. There are many studies on the antibacterial effects of bee products but
Michał Otręba +3 more
wiley +1 more source
Background Mammalian display is an appealing technology for therapeutic antibody development. Despite the advantages of mammalian display, such as full-length IgG display with mammalian glycosylation and its inherent ability to select antibodies with ...
Olli Huhtinen +4 more
doaj +1 more source
Human Immunodeficiency Virus Integrase Pharmacophore Model Derived from Diketoacids Inhibitors [PDF]
Xiaoyi Zhang
openalex +1 more source
Variable orthogonality of serine integrase interactions within the ϕC31 family
Serine integrases are phage- (or mobile element-) encoded enzymes that catalyse site-specific recombination reactions between a short DNA sequence on the phage genome (attP) and a corresponding host genome sequence (attB), thereby integrating the phage ...
Alasdair I. MacDonald +6 more
doaj +1 more source
A Protocol for the Production of Integrase-deficient Lentiviral Vectors for CRISPR/Cas9-mediated Gene Knockout in Dividing Cells [PDF]
Sriram Vijayraghavan, Boris Kantor
openalex +1 more source
Detection of an integrase gene in clinical isolates of Mycobacterium tuberculosis
Introduction: Drug resistance in Mycobacterium tuberculosis (MTB) is caused by many mechanisms. Integrons are genetic units characterized by their ability to capture and incorporate bacterial genomes by recombination and may contain resistance-related ...
M Arjomandzadegan +3 more
doaj
Weight Gain in Incarcerated Individuals Living With HIV After Switching to Integrase Strand Inhibitor-Based Therapy [PDF]
Rachel N. Goldberg +4 more
openalex +1 more source
Activity of recombinant HIV-1 integrase on mini-HIV DNA [PDF]
Peter Cherepanov +6 more
openalex +1 more source

