Results 91 to 100 of about 9,111 (181)

Cytopenias With HIV in the Era of Highly Active Antiretroviral Therapy: Are We Winning the Battle?

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background and Aim Cytopenias remain among the most frequent hematologic complications of HIV infection, affecting treatment outcomes and quality of life. The introduction of highly active antiretroviral therapy has markedly reduced their incidence by restoring immune function and suppressing viral replication.
Emmanuel Ifeanyi Obeagu
wiley   +1 more source

Comparative effectiveness of dolutegravir + lamivudine versus three‐drug regimens in Swedish clinical practice: a nationwide study

Journal of the International AIDS Society, Volume 29, Issue 3, March 2026.
Abstract Introduction HIV guidelines recommend switching from a three‐drug regimen (3DR) to dolutegravir + lamivudine (DTG+3TC) for eligible individuals. This retrospective national cohort study used Swedish InfCareHIV registry data to evaluate long‐term outcomes of adults with HIV RNA <50 copies/ml who switched to DTG+3TC or a guideline‐recommended ...
Erik Sörstedt, George Nduva, Fredrik Månsson, Åsa Mellgren, Johanna Repits, Eva Fernvik, Adam Stubbs, Melanie Schroeder, Johanna Brännström, Christina Carlander   +9 more
wiley   +1 more source

Mycochemical Diversity and Therapeutic Potential of Hymenochaetoid Fungi from Central Asia: Regional and Global Perspectives

New Zealand Journal of Botany, Volume 64, Issue 1, March 2026.
Central Asia harbors a rich yet understudied assemblage of wood‐inhabiting Hymenochaetoid fungi. This review delivers the first comprehensive synthesis of 43 poroid species representing 18 genera documented across montane forests, steppes, and xeric habitats.
Yusufjon Gafforov, Milena Rašeta, Sylvie Rapior, Manzura Yarasheva, Oksana Mykchaylova, Rustamjon Allaberdiev, Şule İnci, Dilfuza Berdieva, Arshad Mehmood Abbasi, Shikhnazar Khodjaev, Dian‐Ming Hu, Weijun Yang, Abudujilili Abuduaini, Maria Letizia Taddei, Mengcen Wang, Islomjon Urinboev, Jiajia Chen   +16 more
wiley   +1 more source

Rhizosphere microbial detoxification and phosphorus solubilization drive ecological remediation of Pb–Zn contaminated soils

PLANTS, PEOPLE, PLANET, Volume 8, Issue 2, Page 639-653, March 2026.
Heavy metal contamination of soils poses a serious threat to ecosystem health and food security worldwide. This study investigated how native plants, such as Artemisia annua and Buddleja davidii, interact with soil microbes in Pb–Zn waste slag areas. We found that these plants stimulate microbes, which improve phosphorus availability and reduce metal ...
Caili Sun, Yajuan Yao, Yongwei Liu, Xiaoyu Lu   +3 more
wiley   +1 more source

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, Volume 22, Issue 16, 17 March 2026.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

vB_CacS-HV1 as a Novel Pahexavirus Bacteriophage with Lytic and Anti-Biofilm Potential against Cutibacterium acnes

Microorganisms
Acne vulgaris is a prevalent chronic inflammatory skin disease, most common in adolescence and often persisting into adulthood, leading to severe physical and psychological impacts. The primary etiological factor is Cutibacterium acnes infection.
Xu Li, Wenyan Ding, Zicheng Li, Yi Yan, Yigang Tong, Jialiang Xu, Mengzhe Li   +6 more
doaj   +1 more source

Genomic Sequencing and Analysis of New Variants of Enzootic Nasal Tumour Virus Type 2 Revealed Recombination Events between Different Sublineages

Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.
The strains from sublineages 1.5 and 1.2 may be promoting the emergence of new strains of ENTV‐2 in China. Recombination drives ENTV‐2's rapid evolution . ABSTRACT In recent years, multiple regions in China have experienced an increase in the occurrence of enzootic nasal tumour virus type 2 (ENTV‐2) infections. This research highlights the initial full
Yong Pan, Li Yang, Ting Li, Jinge Xu, Qiufan Xu, Qi Yang   +5 more
wiley   +1 more source

T‐bet Fate Mapping Reveals Gestational Stage‐Specific Transcriptional Adaptation of Decidual NK Cells

American Journal of Reproductive Immunology, Volume 95, Issue 3, March 2026.
ABSTRACT Problem Natural killer (NK) cells are critical regulators of immune balance at the maternal–fetal interface. T‐bet (Tbx21) is a key transcription factor shaping NK cell effector functions, yet its role in decidual NK (dNK) cell adaptation across gestation remains unclear.
Mona A. Mohamed, Yan Li, Andrea K. Wegrzynowicz, Payton N. Lindner, Jessica Vazquez, Gladys E. Lopez, Aleksandar K. Stanic   +6 more
wiley   +1 more source

Integrase [PDF]

, 2020
openaire   +1 more source

Cas9 beyond CRISPR – SUMOylation, effector‐like potential and pathogenic adaptation

The FEBS Journal, Volume 293, Issue 5, Page 1285-1296, March 2026.
This Viewpoint explores the possibility that Cas9, beyond its canonical role in CRISPR immunity, may act as a host‐modulating effector during infection by Cas9‐encoding bacteria. Such a nucleomodulin‐like function could be influenced by eukaryotic post‐translational modifications, particularly SUMOylation, with potential implications for host–pathogen ...
Umut Sahin
wiley   +1 more source