Genetic characteristics and integration specificity of Salmonella enterica temperate phages
IntroductionTemperate phages can engage in the horizontal transfer of functional genes to their bacterial hosts. Thus, their genetic material becomes an intimate part of bacterial genomes and plays essential roles in bacterial mutation and evolution ...
Siqi Sun, Siqi Sun, Xianglilan Zhang
doaj +1 more source
The ΦBT1 large serine recombinase catalyzes DNA integration at pseudo-attB sites in the genus Nocardia [PDF]
Plasmid vectors based on bacteriophage integrases are important tools in molecular microbiology for the introduction of foreign DNA, especially into bacterial species where other systems for genetic manipulation are limited.
Marion Herisse +8 more
doaj +2 more sources
Directed evolution of hyperactive integrases for site specific insertion of transgenes [PDF]
Ahmed H Badran, Jesse Owens
exaly +2 more sources
Metagenomic analysis of lysogeny in Tampa Bay: implications for prophage gene expression. [PDF]
Phage integrase genes often play a role in the establishment of lysogeny in temperate phage by catalyzing the integration of the phage into one of the host's replicons.
Lauren McDaniel +6 more
doaj +1 more source
Permanent genetic memory with >1-byte capacity [PDF]
Genetic memory enables the recording of information in the DNA of living cells. Memory can record a transient environmental signal or cell state that is then recalled at a later time.
Yang, Lei +6 more
core +4 more sources
Bracoviruses recruit host integrases for their integration into caterpillar's genome.
Some DNA viruses infect host animals usually by integrating their DNAs into the host genome. However, the mechanisms for integration remain largely unknown.
Zehua Wang +11 more
doaj +1 more source
Antiretroviral drugs to prevent integration of the HIV viral genome into chromosomes are undergoing clinical trials, yet they have been developed with an imperfect understanding of their mechanism of action. The recent crystal structure of the major viral protein integrase from a related, little‐known retrovirus, has finally provided insight into how ...
openaire +2 more sources
Gene Loss and Horizontal Gene Transfer Contributed to the Genome Evolution of the Extreme Acidophile “Ferrovum” [PDF]
Indexación: Web of Science. Scopus.Acid mine drainage (AMD), associated with active and abandoned mining sites, is a habitat for acidophilic microorganisms that gain energy from the oxidation of reduced sulfur compounds and ferrous iron and that thrive ...
Daniel, Rolf +7 more
core +2 more sources
Phage integrases for the construction and manipulation of transgenic mammals
Phage integrases catalyze site-specific, unidirectional recombination between two short att recognition sites. Recombination results in integration when the att sites are present on two different DNA molecules and deletion or inversion when the att sites
Sclimenti Christopher R +5 more
doaj +1 more source
Functional Traits Co-Occurring with Mobile Genetic Elements in the Microbiome of the Atacama Desert [PDF]
Mobile genetic elements (MGEs) play an essential role in bacterial adaptation and evolution. These elements are enriched within bacterial communities from extreme environments. However, very little is known if specific genes co-occur with MGEs in extreme
Airo, Alessandro +4 more
core +1 more source

