Results 111 to 120 of about 317,716 (343)

JNK signaling and integrins cooperate to maintain cell adhesion during epithelial fusion in Drosophila

Frontiers in Cell and Developmental Biology
The fusion of epithelial sheets is an essential and conserved morphogenetic event that requires the maintenance of tissue continuity. This is secured by membrane-bound or diffusible signals that instruct the epithelial cells, in a coordinated fashion, to
Katerina Karkali, Jose Carlos Pastor-Pareja, Enrique Martin-Blanco   +2 more
doaj   +1 more source

Geometry‐Guided Osteogenesis in Bone‐on‐a‐Chip Systems Using Triply Periodic Minimal Surface Scaffolds

Advanced Healthcare Materials, EarlyView.
This study presents a bone‐on‐a‐chip platform incorporating TPMS scaffolds to study geometry‐dependent osteogenesis under dynamic flow. By tuning pore shape and solidity, it precisely controls mechanical cues, revealing how topological features and shear stress affect osteogenic differentiation and matrix formation.
Donggyu Kim, Giheon Ha, Minseok Kim, Minjin Kwak, Han‐Jun Kim, Junmin Lee   +5 more
wiley   +1 more source

New Strategy for COVID-19: An Evolutionary Role for RGD Motif in SARS-CoV-2 and Potential Inhibitors for Virus Infection

Frontiers in Pharmacology, 2020
Shijia Yan, Haixia Sun, Xianzhang Bu, Guohui Wan   +3 more
doaj   +1 more source

WISP1-β3 integrin pathway promotes early pulmonary fibrosis through EndMT induced by mechanical ventilation in an experimental sepsis model [PDF]

, 2023
Hongjiao Xu, Jia Hong, Di Liu, Xinwan Wu, Xiaohu Yang, Zhuang Yu   +5 more
openalex   +1 more source

Injectable Dual‐Crosslinked Poly(oligo(Ethylene Glycol) Methacrylate) Hydrogels Inspired by Mussel Adhesion for Cutaneous Wound Healing and Functional Tissue Regeneration

Advanced Healthcare Materials, EarlyView.
Injectable POEGMA‐DA hydrogels, dual‐crosslinked via dopamine self‐polymerization and dynamic hydrazone bonds, provide a safer alternative to invasive wound closure methods and toxic bioadhesives. Mimicking skin‐like mechanics, they achieve effective tissue adhesion for acute dermal wounds, supporting improved healing outcomes, including reducing ...
Gurpreet Kaur Randhawa, Meghan Kostashuk, Zhicheng Pan, Nils Nordstrom, Thomas Kalab, Erica Winterhelt, Todd Hoare   +6 more
wiley   +1 more source

Proteomic Comparison of Acute Myeloid Leukemia Cells and Normal CD34⁺ Bone Marrow Cells: Studies of Leukemia Cell Differentiation and Regulation of Iron Metabolism/Ferroptosis

Proteomes
Acute myeloid leukemia (AML) is an aggressive bone marrow malignancy that can be cured only by intensive chemotherapy possibly combined with allogeneic stem cell transplantation.
Frode Selheim, Elise Aasebø, Håkon Reikvam, Øystein Bruserud, Maria Hernandez-Valladares   +4 more
doaj   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

"Corrigendum: Cancer cell gene expression modulated from plasma membrane integrin alphavbeta3 by thyroid hormone and nanoparticulate tetrac"

Frontiers in Endocrinology, 2015
Paul eDavis
doaj   +1 more source

Collagen I Microfiber Promotes Brain Capillary Network Formation in Three–Dimensional Blood–Brain Barrier Microphysiological Systems

Biomedicines
Background: The blood–brain barrier (BBB) strictly regulates the penetration of substances into the brain, which, although important for maintaining brain homeostasis, may delay drug development because of the difficulties in predicting pharmacokinetics ...
Kimiko Nakayama-Kitamura, Yukari Shigemoto-Mogami, Marie Piantino, Yasuhiro Naka, Asuka Yamada, Shiro Kitano, Tomomi Furihata, Michiya Matsusaki, Kaoru Sato   +8 more
doaj   +1 more source

Integrin trafficking in cells and tissues

Nature Cell Biology, 2019
Paulina Moreno-Layseca, J. Icha, Hellyeh Hamidi, J. Ivaska   +3 more
semanticscholar   +1 more source