Results 161 to 170 of about 86,429 (265)

Transmembrane-4 Superfamily Proteins Associate with Activated Protein Kinase C (PKC) and Link PKC to Specific β1 Integrins

, 2001
Xin A. Zhang, Alexa L. Bontrager, Martin E. Hemler   +2 more
openalex   +1 more source

UBE3A Inhibits Trophoblast Cell Migration and Invasion by Promoting ITGB1 Degradation and Affecting PI3K/AKT Signaling

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Preeclampsia (PE) is an obstetric disease that is characterized by reduced migration and invasion of placental trophoblast cells. Here, the effects of the E3 ubiquitin ligase UBE3A on the migration and invasion of trophoblast cells were evaluated.
Xiu‐Jun Li, Ning Wang, Fan Jiang, Jie‐Cheng Yang, Yan‐Yun Wang, Kun Wang   +5 more
wiley   +1 more source

Silencing profilin-1 inhibits gastric cancer progressionviaintegrin β1/focal adhesion kinase pathway modulation

, 2015
Yajun Cheng
openalex   +2 more sources

The Cell-binding Domain of Intimin from Enteropathogenic Escherichia coli Binds to β1 Integrins [PDF]

, 1996
Gad Frankel, Ofer Lider, Rami Hershkoviz, A. Paul Mould, Sylvia G. Kachalsky, D. C. A. Candy, Liora Cahalon, Martin J. Humphries, Gordon Dougan   +8 more
openalex   +1 more source

CRISPR Enabled Precision Oncology: From Gene Editing to Tumor Microenvironment Remodeling

Med Research, EarlyView.
CRISPR technology has progressed from a prokaryotic immune system to a diverse suite of editing platforms, including Cas nucleases, base and prime editors, and RNA‐targeting enzymes. These advances enable precise genomic and epigenomic interventions, high‐throughput functional screening, and immune engineering.
Kailai Li, Peixin Huang, Yue Qian, Anqi Lin, Jingjun He, Junyi Shen, Li Chen, Kai Miao, Jian Zhang   +8 more
wiley   +1 more source

Increase in β1‐6 GlcNAc branching caused by N‐acetylglucosaminyltransferase V directs integrin β1 stability in human hepatocellular carcinoma cell line SMMC‐7721 [PDF]

, 2006
Liying Wang, Yulong Liang, Zengxia Li, Xiumei Cai, Wen Zhang, Guoqiang Wu, Jiawei Jin, Zhengyu Fang, Yong Yang, Xiliang Zha   +9 more
openalex   +1 more source

Respiratory Syncytial Virus (RSV): A Comprehensive Overview From Basic Biology to Clinical Prevention and Control

Medicinal Research Reviews, EarlyView.
ABSTRACT Respiratory syncytial virus (RSV) is a common virus that causes respiratory infections, posing a serious threat, particularly to infants, the elderly, and individuals with compromised immune systems. As the leading cause of lower respiratory tract infections (LRTIs) in infants, RSV is responsible for millions of cases worldwide each year.
Jie Shi, Xiya Huang, Chunjun Ye, Yishan Lu, Yanyan Liu, Yuquan Wei, Xiawei Wei   +6 more
wiley   +1 more source

Cullin-3 regulates the renal baroreceptor machinery that controls renin gene expression

JCI Insight
Mutations in Cullin-3 (CUL3) cause hypertension (HTN). We examined the role of smooth muscle cell (SMC) CUL3 in the regulation of renin gene expression.
Daria Golosova, Gaurav Kumar, Ko-Ting Lu, Patricia C. Muskus Veitia, Ana Hantke Guixa, Kelsey K. Wackman, Eva M. Fekete, Daniel T. Brozoski, Justin L. Grobe, Maria Luisa S. Sequeira-Lopez, R. Ariel Gomez, Pablo Nakagawa, Curt D. Sigmund   +12 more
doaj   +1 more source

High threshold of β1 integrin inhibition required to block collagen I-induced membrane type-1 matrix metalloproteinase (MT1-MMP) activation of matrix metalloproteinase 2 (MMP-2) [PDF]

, 2014
Kulrut Borrirukwanit, Prasit Pavasant, Tony Blick, Marc A. Lafleur, Erik W. Thompson   +4 more
openalex   +1 more source

Supplementary Data from The β1-Integrin–Dependent Function of RECK in Physiologic and Tumor Angiogenesis [PDF]

, 2023
Takao Miki, Awad Shamma, Shunsuke Kitajima, Yujiro Takegami, Makoto Noda, Yasuaki Nakashima, Kenichiro Watanabe, Chiaki Takahashi   +7 more
openalex   +1 more source