Results 211 to 220 of about 105,036 (265)

The role of extracellular matrix stiffness in regulating fibroblast behaviors and disease progression. [PDF]

open access: yesFront Immunol
Fan Z   +9 more
europepmc   +1 more source

Integrins and Disease

Clinical Science, 1996
1. Adhesion is a vital property of cells. It provides a stable environment for cell growth and differentiation and allows cells to migrate. 2. The interaction between cells and their extracellular matrices is also an important factor in the regulation of further protein deposition.
G S, Hillis, A M, MacLeod
openaire   +2 more sources

Leukocyte integrins

Current Opinion in Cell Biology, 1995
Lymphocytes, monocytes and granulocytes, which are collectively known as 'leukocytes', circulate primarily within the vascular system and lymphoid tissue but are found in essentially all tissues of the body. This mobile lifestyle necessitates the constant making and breaking of adhesive contacts with targets in their immediate environment. The adhesion
M, Stewart, M, Thiel, N, Hogg
openaire   +2 more sources

Integrins and reproduction

European Journal of Obstetrics & Gynecology and Reproductive Biology, 1995
Integrins are a large family of cell surface proteins that serve as receptors, involved in cell-cell and cell-matrix interactions. These receptors are of fundamental importance in the organization of tissues and organs. Integrins participate in a complex apparatus anchoring cells to their surrounding and transducing signals into the cells.
openaire   +3 more sources

Integrin Structure

Biochemical Society Transactions, 2000
The integrins are a family of α,β heterodimeric receptors that mediate dynamic linkages between extracellular adhesion molecules and the intracellular actin cytoskeleton. Integrins are expressed by all multicellular animals, but their diversity varies widely among species; for example, in mammals, 19 α and 8β subunit genes encode polypeptides that ...
openaire   +3 more sources

Integrins and cancer

Current Opinion in Cell Biology, 1996
The past year or two has seen great advances in the elucidation of significant roles for integrins in cancer cells. These include roles in signal transduction, gene expression, proliferation, apoptosis regulation, invasion and metastasis, and angiogenesis. In particular, integrin alphavbeta3 has been implicated in the neovascularization of tumors.
J A, Varner, D A, Cheresh
openaire   +2 more sources

Integrins and Angiogenesis

2004
The growth of new blood vessels is a dynamic yet highly regulated process that depends on coordinated signaling by growth factor and cell adhesion receptors. As part of the molecular program regulating angiogenesis, endothelial cells acquire a proliferative and invasive phenotype but also show increased susceptibility to apoptotic stimuli.
D G, Stupack, D A, Cheresh
openaire   +2 more sources

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