Results 211 to 220 of about 101,656 (264)

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng   +5 more
wiley   +1 more source

Kindlins regulate integrin- and growth factor-dependent ureteric bud formation. [PDF]

open access: yesDevelopment
Li S   +14 more
europepmc   +1 more source

Integrin-Binding Matricellular Protein Fibulin-5 Maintains Epidermal Stem Cell Heterogeneity During Skin Aging. [PDF]

open access: yesAging Cell
Fan W   +9 more
europepmc   +1 more source

Editorial: Exploring the role of exosomes in cancer metastasis. [PDF]

open access: yesFront Pharmacol
Kalvala AK, Pooladanda V, Kommineni N.
europepmc   +1 more source

<i>ITGA4</i> genetic variants as a predictor of therapeutic responsivity to autoimmune diseases. [PDF]

open access: yesFront Pharmacol
De Matos MD   +5 more
europepmc   +1 more source

Detection of Mesenchymal Stem Cell Aging Using an Integrin Mechano-Probe. [PDF]

open access: yesAnn N Y Acad Sci
Liu A   +10 more
europepmc   +1 more source

Integrins and Disease

Clinical Science, 1996
1. Adhesion is a vital property of cells. It provides a stable environment for cell growth and differentiation and allows cells to migrate. 2. The interaction between cells and their extracellular matrices is also an important factor in the regulation of further protein deposition.
G S, Hillis, A M, MacLeod
openaire   +2 more sources

Integrins and cancer

Current Opinion in Cell Biology, 1996
The past year or two has seen great advances in the elucidation of significant roles for integrins in cancer cells. These include roles in signal transduction, gene expression, proliferation, apoptosis regulation, invasion and metastasis, and angiogenesis. In particular, integrin alphavbeta3 has been implicated in the neovascularization of tumors.
J A, Varner, D A, Cheresh
openaire   +2 more sources

Integrins and Angiogenesis

2004
The growth of new blood vessels is a dynamic yet highly regulated process that depends on coordinated signaling by growth factor and cell adhesion receptors. As part of the molecular program regulating angiogenesis, endothelial cells acquire a proliferative and invasive phenotype but also show increased susceptibility to apoptotic stimuli.
D G, Stupack, D A, Cheresh
openaire   +2 more sources

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