Results 221 to 230 of about 221,644 (354)

Fibrillar adhesions are the primary integrin complexes shaped by matrix topography

open access: gold
Aaron J. Farrugia   +14 more
openalex   +1 more source

Integrin On, Integrin Off♦

open access: yesJournal of Biological Chemistry, 2008
openaire   +1 more source

Electrical Control of the Transduction Channels’ Gating Force in Mechanosensory Hair Cells

open access: yesAdvanced Science, EarlyView.
The inner ear's hair cells rely on mechanosensitive ion channels to convert vibrations of their hair‐bundle into electrical signals. We show that varying the electrical potential (U) across the sensory epithelium modulates a key determinant of mechanosensitivity—the gating force (FG)—by modulating the gating swing (d), ranging from the size of the ...
Achille Joliot   +2 more
wiley   +1 more source

Focal Adhesion and Cancer Cell Cycle-Associated Resistance. [PDF]

open access: yesACS Omega
Ruksha TG   +3 more
europepmc   +1 more source

A novel form of integrin dysfunction involving beta 1, beta 2, and beta 3 integrins [PDF]

open access: yes, 2003
Hogg, N   +6 more
core  

DEL‐1 is an Endogenous Senolytic Protein that Inhibits Senescence‐Associated Bone Loss

open access: yesAdvanced Science, EarlyView.
Senescent bone marrow stromal cells accumulate in the aging bone microenvironment, promoting bone degeneration. DEL‐1, an endogenous secreted protein, acts as a natural senolytic that selectively eliminates these cells. By engaging a β3 integrin/CD73/adenosine/p38 MAPK/BCL‐2 pathway, DEL‐1 counters aging‐related bone loss, revealing promising ...
Jong‐Hyung Lim   +11 more
wiley   +1 more source

Decoding Human Placental Cellular and Molecular Responses to Obesity and Fetal Growth

open access: yesAdvanced Science, EarlyView.
Women with obesity often deliver large‐for‐gestational‐age (LGA) infants. Single‐nucleus RNA sequencing of term placenta reveals that hypoxia and TNF‐α signaling in syncytiotrophoblasts are featured in maternal obesity, but inflammatory signatures in Hofbauer cells and response to lipid or carbohydrate metabolism in fibroblasts are specific to LGA.
Hong Jiang   +12 more
wiley   +1 more source

The emerging role of human transmembrane RGD-based counter-receptors of integrins in health and disease. [PDF]

open access: yesCell Mol Biol Lett
Cabañas C   +6 more
europepmc   +1 more source

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