Results 231 to 240 of about 299,855 (390)

Anoikis resistance in gastric cancer: a comprehensive review. [PDF]

Cell Death Dis
D'Amore T, Bravoco D, Di Paola G, Albano F, Brancaccio M, Sabato C, Cesta G, Zolfanelli C, Lauciello V, Falco G, Mazzone P.   +10 more
europepmc   +1 more source

A point mutation in the integrin beta 3 cytoplasmic domain (S752-->P) impairs bidirectional signaling through alpha IIb beta 3 (platelet glycoprotein IIb-IIIa) [PDF]

, 1994
YP Chen, TE O'Toole, Jari Ylänne, JP Rosa, MH Ginsberg   +4 more
openalex   +1 more source

Artesunate Nanoplatform Targets the Serine–MAPK Axis in Cancer‐Associated Fibroblasts to Reverse Photothermal Resistance in Triple‐Negative Breast Cancer

Advanced Materials, EarlyView.
The artesunate nanoplatform selectively targets ECM CAF, functioning as a GTPase inhibitor through disruption of intracellular serine homeostasis. This metabolic intervention effectively suppresses MAPK cascade activity, which consequently inhibits PTT‐induced CAF to ECM CAF differentiation.
Dongdong Zheng, Jiaqi Yan, Xuejiao Liu, Zhiming Zhang, Anqi Jin, Yue Zhao, Lu Bai, Mengyao Quan, Xiuzhu Qi, Bin Fu, Zhigang Wu, Jin Zhou, Han Han, Ziqi Wang, Shiyu Wang, Chaoqiang Deng, Weijian Sun, Cai Chang, Shichong Zhou, Hongbo Zhang   +19 more
wiley   +1 more source

Mammalian cells measure the extracellular matrix area and respond through switching the adhesion state. [PDF]

Nat Commun
Wang X, Wang P, Zhang L, Xu T, Ahn S, Sharma U, Yu H, Strohmeyer N, Müller DJ.   +8 more
europepmc   +1 more source

Functional role of the cytoplasmic domain of the integrin alpha 5 subunit [PDF]

, 1993
JS Bauer, Judith A. Varner, Cynthia Schreiner, Lori J. Kornberg, Robert A. Nicholas, RL Juliano   +5 more
openalex   +1 more source

Kank2 activates talin, reduces force transduction across integrins and induces central adhesion formation

Nature Cell Biology, 2016
Zhiqi Sun, Hui-yuan Tseng, Steven J. Tan, Fabrice Senger, Laetitia Kurzawa, D. Dedden, N. Mizuno, A. Wasik, M. Théry, A. Dunn, R. Fässler   +10 more
semanticscholar   +1 more source

Biomimetic Cell Membrane‐Coated Scaffolds for Enhanced Tissue Regeneration

Advanced Materials, EarlyView.
This review examines the development and use of cell membrane‐coated scaffolds in tissue engineering. Bioinspired phospholipid and glycocalyx coatings enhance anti‐fouling, anti‐thrombogenic, and selective molecular recognition properties. Native cell membrane coatings further support cell‐specific interactions, immune modulation, and reduced bacterial
Carmen Alvarez‐Lorenzo, Alejandro Ramirez‐Romero, Diana Peixoto, Maria Vivero‐Lopez, Isabel Rodríguez‐Moldes, Angel Concheiro   +5 more
wiley   +1 more source

Age-Related Dysregulation of α5β1 and αvβ3 Integrin Activity Alters Contractile Properties of Trabecular Meshwork Cells. [PDF]

Invest Ophthalmol Vis Sci
Johns KL, Faralli JA, Filla MS, Shah NS, Sun YY, Keller KE, Peters DM.   +6 more
europepmc   +1 more source

Immune complex-stimulated neutrophil LTB4 production is dependent on beta 2 integrins. [PDF]

, 1993
Irene Graham, J B Lefkowith, D C Anderson, Eric J. Brown   +3 more
openalex   +1 more source

Nanostructured Protein Surfaces Inspired by Spider Silk

Advanced Materials, EarlyView.
Harnessing recombinant spider silk technology, bioengineered spidroin variants enable the creation of functionalized nanostructured coatings with tunable affinity for specific targets, supporting a broad range of applications ‐ from antifouling surfaces and targeted drug delivery to advanced cell therapies and precision bio‐patterning via lithography ...
Martin Humenik, Thomas Scheibel
wiley   +1 more source