Results 111 to 120 of about 349,914 (309)

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Dispersive Optical Wireless Indoor Channels—From Frequency-Domain Modeling to Bit-Error-Rate Prediction

IEEE Photonics Journal
Methods for calculating the impulse response of dispersive optical wireless channels have been known for a long time. However, a comprehensive procedure for predicting resulting bit error rates, starting from a highly accurate channel emulation method ...
Henrik Schulze, Jan Mietzner, Peter Adam Hoeher   +2 more
doaj   +1 more source

Intensity Noise of InGaAsP/InP Lasers under the Influence of Reflection and Modulation [PDF]

, 1982
Hideo Kuwahara, H. Imai
openalex   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source

The Influence of Diode Laser Intensity Modulation on Photoacoustic Image Quality for Oral Soft Tissue Imaging. [PDF]

J Lasers Med Sci, 2020
Widyaningrum R, Mitrayana M, Sola Gracea R, Agustina D, Mudjosemedi M, Miyosi Silalahi H.   +5 more
europepmc   +1 more source

Electronic polarization-division demultiplexing based on digital signal processing in intensity-modulation direct-detection optical communication systems

, 2014
Kumiko Kikuchi
openalex   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Affective Modulation after High-Intensity Exercise Is Associated with Prolonged Amygdalar-Insular Functional Connectivity Increase [PDF]

, 2020
Angelika Schmitt, Neeraj Upadhyay, Jason Martin, Sandra Rojas Vega, Heiko K. Strüder, Henning Boecker   +5 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

An Economic Phase-Mdulation to Intensity-Modulation Converter

, 2013
Ching-Hung Chang, Jui-Hsuan Chang, Yin-Liang Liao, Meng Chun Tseng   +3 more
openalex   +2 more sources