Results 71 to 80 of about 513,377 (289)

Cardiac sodium channel NaV1.5 distribution in myocytes via interacting proteins: the multiple pool model

open access: yes, 2013
The cardiac sodium current (INa) is responsible for the rapid depolarization of cardiac cells, thus allowing for their contraction. It is also involved in regulating the duration of the cardiac action potential (AP) and propagation of the impulse ...
Shy, Diana   +2 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Orientation Estimation for Sensor Motion Tracking using Interacting Multiple Model Filter

open access: yes, 2014
[[abstract]]In this letter, we present a real-time orientation estimation and motion tracking scheme using interacting multiple model (IMM) based Kalman filtering method.
WANN, Chin-Der;GAO, Jian-Hau
core   +1 more source

Multiplicative model for spatial interaction in the human visual cortex

open access: yesJournal of Vision, 2008
Multifocal visual evoked potentials (mfVEP) were recorded simultaneously for both the target and the neighbor stimuli, each varying over 6 levels of contrast: 0%, 4%, 8%, 16%, 32%, and 64%. For most conditions, the relationship between the amplitude of target response and the contrast of the neighbor stimulus, as well as the amplitude of the response ...
Xian, Zhang   +5 more
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Taxiing Tracking Algorithm of Aircraft on the Ground Based on the Runway-taxiway System Constraints

open access: yes四川大学学报. 自然科学版, 2019
In order to solve the airport surface confliction problem in large airports, a variable structure interacting multiple model algorithm based on runwaytaxiway system constraint and ATC order constraint is applied to the tracking of field targets.
panweijun   +3 more
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Enhancing Object Estimation by Camera-LiDAR Sensor Fusion Using IMM-KF With Error Characteristics in Autonomous Robot Systems

open access: yesIEEE Access
In autonomous robot systems, accurate object recognition and estimation are crucial for ensuring reliable performance, and sensor fusion techniques that combine complementary sensors have proven to be effective in achieving this.
Sun Ho Lee, Woo Young Choi
doaj   +1 more source

An adaptive interacting multiple model for vehicle target tracking method

open access: yes, 2013
In the field of traffic safety vehicle target tracking prediction as the background, this paper proposes an adaptive interacting multiple model tracking algorithm.
Bi X(毕欣), Du JS(杜劲松)
core  

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