Results 91 to 100 of about 17,756,051 (243)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Application of interacting multiple model in integrated positioning system of vehicle

Journal of Measurement Science and Instrumentation, 2018
To solve low precision and poor stability of the extended Kalman filter（EKF）in the vehicle integrated positioning system owing to acceleration,deceleration and turning（hereinafter referred to as maneuvering）,the paper presents an adaptive filter ...
WEI Wen-jun, GAO Xue-ze, GE Li-min, GAO Zhong-jun   +3 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Survival Measures and Interacting Intensity Model: with Applications in Guaranteed Debt Pricing [PDF]

This paper studies survival measures in credit risk models. Survival measure, which was first introduced by Schonbucher [12] in the framework of defaultable LMM, has the advantage of eliminating default indicator variable directly from the expectation by
Liu, Guimei, Bao, Qunfang, Li, Shenghong
core  

An Adaptive IMM Algorithm for a PD Radar with Improved Maneuvering Target Tracking Performance

Remote Sensing
A pulse-Doppler (PD) radar has the advantage of strong anti-interference ability, and it is often used as a solution for maneuvering target tracking.
Wenwen Xu, Jiankang Xiao, Dalong Xu, Hao Wang, Jianyin Cao   +4 more
doaj   +1 more source

Model selection mechanism of Interactive Multiple Load Modeling

International Journal of Electrical Power & Energy Systems, 2018
Abstract Accurate load modeling with fluctuate loads has been one of the most challenging problems of modern power system. In this paper, a model selection mechanism is proposed for the Interacting Multiple Load Modeling (IMLM), to achieve the adaptive adjustment of best model set. A large number of models with different characteristics are chosen to
Zhenshu Wang, Na Ji, Yangyang Ma, Zhanjie Liu, Yu Wang   +4 more
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A Hybrid Land Conversion Model Incorporating Multiple End Uses [PDF]

The need for models that forecast land use change spans many disciplines and encompasses many approaches. Pattern-based models were the first in which projections of change at specific locations in actual landscapes could be predicted.
Towe, Charles A., Ye, Xin, Kaza, Nikhil
core  

A Cost-Effective Vehicle Localization Solution Using an Interacting Multiple Model−Unscented Kalman Filters (IMM-UKF) Algorithm and Grey Neural Network

Sensors, 2017
In this paper, we propose a cost-effective localization solution for land vehicles, which can simultaneously adapt to the uncertain noise of inertial sensors and bridge Global Positioning System (GPS) outages. First, three Unscented Kalman filters (UKFs)
Qimin Xu, Xu Li, Ching-Yao Chan
doaj   +1 more source