Results 111 to 120 of about 5,238,966 (190)

Compliance in Regulatory Gray Areas: The Case of the Organic Seed Standard

open access: yesPolicy Studies Journal, Volume 54, Issue 4, November 2026.
ABSTRACT Adaptive regulations, designed to balance flexibility with accountability, can embed provisions that unintentionally leave room for firms to shirk on their responsibilities by exploiting flexibility. We call these provisions “regulatory gray areas,” and ask: how should we understand (non‐)compliance in adaptive regulatory settings?
Liza Wood   +3 more
wiley   +1 more source

Beyond Evidence: How Framing Shapes Public Health Policies During Health Crises

open access: yesPolicy Studies Journal, Volume 54, Issue 4, November 2026.
ABSTRACT Does the level of evidence that accompanies policy action depend on how a problem is framed, and on who frames it? This article examines these questions in the context of health crises. Bridging sociological and equivalence framing theories, it treats frames as preexisting interpretive schemes shared within communities of actors, whose ...
Antoine Claude Lemor, Eric Montpetit
wiley   +1 more source

The Politics of Policy Change in the European Union's Nature Restoration Regulation: An Integrative Approach

open access: yesReview of Policy Research, Volume 43, Issue 6, November 2026.
ABSTRACT The EU policy framework for nature restoration has undergone a significant change with the adoption of the Nature Restoration Regulation. Since 2022, the EU has developed a new comprehensive and continent‐wide legislation to restore degraded ecosystems and halt biodiversity loss, which came into force in August 2024 and is an integral part of ...
Ronit Justo‐Hanani
wiley   +1 more source

Who Owns the Landscape? Policy Conflict Over the Proposed Designation of Křivoklátsko as a National Park

open access: yesReview of Policy Research, Volume 43, Issue 6, November 2026.
ABSTRACT Nature conservation conflicts increasingly extend beyond ecological objectives to disputes over decision‐making legitimacy, institutional authority, and competing understandings of landscape and expertise. This article examines the conflict over the proposed designation of Křivoklátsko as a national park in the Czech Republic between 2021 and ...
Filip Simon
wiley   +1 more source

利用自组装单分子层(SAM)研究细胞和表面的相互作用

open access: yes, 2001
研究细胞和表面相互作用具有重要意义 ,利用长链的烷硫醇在金表面或烷基硅烷在羟基化表面形成的自组装单分子层及其微格式化的表面允许以分子水平研究并控制细胞和表面的相互作用 ...
应佩青, 王战会
core   +1 more source

整合素-ICAM-1相互作用的二维反应动力学研究

open access: yes, 2009
_2整合素(LFA-1和Mac-1)与其配体细胞间粘附分子-1(ICAM-1)的相互作用在诸如肿瘤转移、炎症反应等许多病理生理过程中起着重要的作用。研究表明,中性粒细胞(PMN)在特定环境下可通过_2整合素与ICAM-1的相互作用而增强黑色素瘤细胞的转移能力,但是其动力学调控机制还不清楚。受体-配体键结合和解离的二维反应动力学定量描述了分子结合的快慢和强弱,是回答_2整合素与ICAM ...
龙勉   +4 more
core   +1 more source

Physiological measurement and screening of key genes of the rhizome cold tolerance in the herbaceous peony cultivated over winter in Harbin(哈尔滨越冬栽培的芍药根茎耐寒生理测定和关键基因筛选)

open access: yes浙江大学学报. 农业与生命科学版
Paenonia lactiflora Pall. is a renowned traditional Chinese flower, and it is of great significance to study its cold tolerance mechanism for breeding new varieties and expanding its popularization.
王琪瑶(WANG Qiyao)   +7 more
doaj   +1 more source

伽马射线照射对小鼠肠道干细胞及分化细胞关键基因的影响及鉴定

open access: yesFushe yanjiu yu fushe gongyi xuebao
研究γ射线对小鼠肠道中肠道干细胞及其分化细胞表达谱的影响,筛选关键基因。利用Seurat包对单细胞数据(GSE165318)进行聚类分析和差异表达分析,通过TCseq包进行时间序列的表达趋势分析,对肠道干细胞及分化细胞的差异上调基因和特定趋势基因簇取交集得到关键基因。分别采用clusterProfiler软件包和STRING数据库对关键基因进行基因本体(Gene ontology,GO)富集分析和蛋白质-蛋白质相互作用网络分析(Protein-protein interaction,PPI ...
张 浩然   +5 more
doaj   +1 more source

芯片表面蛋白质分子相互作用动态模型

open access: yes, 2013
蛋白质通过彼此之间的相互作用来共同完成生物体的生理生化功能。因此,研究蛋白质的相互作用是理解生命活动的基础,对蛋白质相互作用动力学的研究有助于系统地认识蛋白质结构与功能的关系。目前,描述蛋白质分子相互作用的模型均采用简化后的蛋白质分子吸附模型。蛋白质分子相互作用表面并无特异性的结合位点,动力学模型需要与实验结合,通过近似得到动力学参数,而无法实现对反应动力学过程的预测。本研究提出一种能够描述和预测蛋白质分子间的特异性相互作用的动力学模型,它的建立基于全内反射椭偏成像生物传感器 ...
康腾飞, 郝文欣, 靳刚, 罗子人
core   +1 more source

基于微阵列技术探究帕金森病相关免疫特征的研究

open access: yesZhongguo shiyan zhenduanxue
目的利用公开的帕金森病(Parkinson’s disease,PD)外周血的基因表达谱数据,通过免疫浸润分析其免疫差异,利用差异基因分析、构建蛋白-蛋白相互作用(Protein-protein interaction,PPI)网络,寻找PD新的潜在生物标志物,为探究PD的相关免疫特征提供新的思路。方法本研究所用的基因转录组RNA测序数据(GSE6613和GSE57475)和患者临床性状相关数据均来源于GEO数据库。外周血转录组数据包括50例PD、93例早期帕金森病(Early Parkinson’s ...
何敏   +6 more
doaj  

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